Search Results - proteomics

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Compounds and methods of identifying novel E3 ligases for targeted protein degradation
NU 2023-096 INVENTORS Ananya Angela Basu Xiaoyu Zhang* SHORT DESCRIPTION A CRISPR-activation screen for discovering E3 ligases amenable to targeted protein degradation, and a novel PROTAC for FBXO22 BACKGROUND Traditional small molecule drugs function by directly interfering with the activities of proteins. However, many proteins lack suitable...
Published: 10/3/2024   |   Inventor(s):  
Keywords(s): Drug discovery, Proteomics, Small molecule
Category(s): Life Sciences > Therapeutics
Software System for Analysis of Extremely Large Experimental Dataset and Multidimensional Drug Discovery
Abstract: The National Institute on Aging, Laboratory of Neurosciences-Receptor Pharmacology Unit is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize biomedical informatics. This invention is a computer software suite that will enable its user to investigate...
Published: 10/28/2024   |   Inventor(s): Stuart Maudsley, Tie Yi, Bronwen Martin
Keywords(s): gene arrays, proteomics, RESEARCH TOOL, software
Category(s): Application > Research Materials, Collaboration Sought > Licensing
SCITO-SEQ: SINGLE CELL COMBINATORIAL INDEXED CYTOMETRY SEQUENCING
SCITO-SEQ: SINGLE CELL COMBINATORIAL INDEXED CYTOMETRY SEQUENCING Researchers at UCSF have developed SCITO-seq, a new workflow for single cell sequencing-based proteomics. The use of DNA to barcode and tag antibodies has created new opportunities to use sequencing to profile the molecular properties of thousands of cells simultaneously. Furthermore,...
Published: 1/19/2024   |   Inventor(s): Chun Ye, Byungjin Hwang, David Lee
Keywords(s): Antibody, Droplet-Based Single Cell Sequencing, dsc-Seq, Microfluidics, Proteomics, Single Cell, Single Cell Analysis
Category(s): Technology Classifications > Biology
A Nanopore Method for Identifying Single Amino Acid in Oligopeptides
Reference #: 01471 The University of South Carolina is offering licensing opportunities for A Nanopore Method for Identifying Single Amino Acid in Oligopeptides Background: The primary sequence of a protein or a peptide is essential to its identification and function. In the area of personalized diagnosis and therapeutics, an accurate proteomic information...
Published: 4/18/2024   |   Inventor(s): Chang Liu, Qian Wang
Keywords(s): amino acid, derivatization, identification, nanopore, proteomics
Category(s): Chemistry and Biochemistry, Nanotechnology, Health Sciences