Search Results - caspase

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Caspase Inhibitors Useful for the Study of Autoimmune or Inflammatory Diseases
Novel and potent caspase 1 inhibitors are available for licensing. In particular, this technology discloses potent and selective caspase 1 inhibitors that target the active site of the enzyme. Caspase 1 is known to play a pro-inflammatory role in numerous autoimmune and inflammatory diseases and therefore represents an excellent target for treatment...
Published: 10/28/2024   |   Inventor(s): Matthew Boxer, Craig Thomas
Keywords(s): 1, Amyotrophic lateral sclerosis, Amyotrophic lateral sclerosis 1; Amyotrophic lateral scleros, Amyotrophic lateral sclerosis 6, Caspase, IB3XXX, IBXXXX, Inflammatory bowel disease 1, inhibitor, IXXXXX, Lou Gehrig's disease, Patent Category - Chemistry
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Immunology
Novel Peptides: Effective Therapeutics for Late Stage Prostate and Other EZH2-Dependent Cancers
Project ID: D2009-27Background: Prostate cancer, the second leading cause of cancer deaths among men, largely depends upon androgens for its development and progression. The importance of the Androgen Receptor in the development of prostate cancer is demonstrated by the success of anti-androgen therapy at the early stages of prostate cancer. Hormone...
Published: 5/9/2024   |   Inventor(s): Lirim Shemshedini, Shao-Yong Chen, Changmeng Cai, Chen-Lin Hsieh
Keywords(s): Caspase, In vivo, Kit, Prostate Cancer, sGCa1
Category(s): Oncology