Search Results - zhenglin+yang

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Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 3/4/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
DNAzyme sensor for selective manganese ion detection in biological systems
A selective DNAzyme-based fluorescent sensor detects manganese ions in cells by lighting up when Mn²⁺ binds, allowing precise monitoring of manganese levels for biological research and potential therapies. Background Manganese (Mn²⁺) is an essential trace element integral to numerous biological processes, acting as a vital cofactor for enzymes...
Published: 1/31/2025   |   Inventor(s): Yi Lu, Zhenglin Yang, Huanhuan Fan
Keywords(s):  
Category(s): Life sciences > Biomaterials
DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions
Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...
Published: 1/31/2025   |   Inventor(s): Yi Lu, Seyed-Fakhreddin Torabi, Yuting Wu, Ryan Lake, Zhenglin Yang, Peiwen Wu, Whitney Lewis, Jacqueline Van Stappen, Xiangli Shao
Keywords(s):  
Category(s): Life sciences > Biomaterials
Steric Hindrance Effect of Additives for Tuning the Perovskite Crystal Orientation (Case No. 2024-023)
Summary: UCLA Researchers in the Department of Materials Science and Engineering have developed a method to tune perovskite crystal orientation for increased performance, energy efficiency, and reduced material defect with a variety of field applications, including solar cells and LEDs. Background: Perovskite holds considerable promise as a highly...
Published: 2/14/2025   |   Inventor(s): Yang Yang, Chunqing Ma, Haoxiang Duan, Dong Meng
Keywords(s): Energy Efficiency, energy-efficient, Imaging, Liquid-Crystal Display, Nanocrystal, OLED, Optoelectronics, organic photo detector, organic photovoltaics, perovskite, perovskite devices, perovskite solar cell, photodetection, Solar Cell, X-ray detectors
Category(s): Chemical > Chemical Processing & Manufacturing, Energy & Environment > Energy Efficiency, Energy & Environment, Materials > Composite Materials, Optics & Photonics, Optics & Photonics > Fiber Optics, Materials > Functional Materials
2023-087 Thiophene Configurable Amorphous Small Molecular Hole Transporting Material for Efficient and Stable Perovskite Solar Cell
Summary: UCLA researchers in the Department of Materials Science and Engineering have invented a series of hole transporting materials that have enabled among the highest recorded power conversion efficiencies for perovskite solar cells while maintaining high device stability and low cost. Background: Perovskite solar cells (PSCs) are an emerging...
Published: 2/14/2025   |   Inventor(s): Yang Yang, Dong Meng
Keywords(s): buffer layer, charge collection, charge collection efficiency, charge extraction, charge-transfer, device architectures, device stability, hole transporting material, hydrophobicity, interfacial layer, ion-migration, n-i-p device, perovskite, Perovskite Lead(II) Iodide, perovskite solar cell, photostability, p-i-n device, power conversion efficiency, radiosurgery, Silicon Working Electrode Perovskite (Structure), spinal surgery, thermal stability
Category(s): Chemical, Electrical, Energy & Environment > Energy Generation > Solar, Materials, Materials > Functional Materials, Electrical > Electronics & Semiconductors
Intermetallic Fe Based Catalysts for Light Olefin Production
­Advantages: High Selectivity: Up to 45% light olefin selectivity with CO2 included. Exceptional Stability: Maintains performance over a 72-hour run. Customizable Reactivity: Fe:In ratios tune surface composition for optimized olefin production and reduced by-products. Summary: This technology addresses a critical need in the chemical industry...
Published: 8/22/2024   |   Inventor(s): John Kuhn, Babu Joseph, Yang He
Keywords(s): Chemistry and Chemical Engineering, Material Science
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Energy & Environment > Energy Engineering
An OCT method to improve scleral lens fitting
Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...
Published: 1/5/2024   |   Inventor(s): David Huang, Yan Li, Clara Llorens Quintana
Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Imaging, Software
High-Throughput Direct-Measurement of Telomere Length
Telomeres are linear chromosome end-capping repetitive DNA sequences. They serve to protect the ends of chromosomes from undesirable fusion events, thus integrity and length are crucial for stability. Natural attrition as well as mutations can affect telomere integrity and length resulting in chromosome instability, senescence, cell death and human...
Published: 2/13/2025   |   Inventor(s): Julian Chen, Yang Li, Dhenugen Logeswaran
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors
Learning Sparse Features for Self-Supervised Learning with Contrastive Dual Gating
The success of conventional supervised learning relies on large-scale labeled datasets to achieve high accuracy. However, annotating millions of data samples is labor-intensive and time-consuming. This promotes self-supervised learning as an attractive solution with artificial labels being used instead of human-annotated ones for training. Contrastive...
Published: 2/13/2025   |   Inventor(s): Jae-Sun Seo, Jian Meng, Li Yang, Deliang Fan
Keywords(s): Algorithm Development, Machine Learning, Performance Optimization, PS-Computing and Information Technology
Category(s): Computing & Information Technology, Physical Science
New Small Molecules for Stable and Efficient Organic Photovoltaics (UCLA Case No. 2023-086)
Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel molecule for organic photovoltaics, photodetectors, organic field effect transistors, and other relevant applications. Background: Among all competing photovoltaic technologies, the organic photovoltaics (OPVs) market is likely to grow the fastest,...
Published: 2/14/2025   |   Inventor(s): Yang Yang, Dong Meng
Keywords(s): Concentrated Solar Power, Concentrated Solar Power Chemical Engineering, energy conversion, energy conversion applications, energy recycle, interfacial layer, Methods Of Detecting Extrasolar Planets, multi-junction tandem devices, near-infrared, organic field effect transistors, organic photo detector, organic photovoltaics, Organic Solar Cell, perovskite devices, perovskite solar cell, Polymer Solar Cell, rganic light-emitting diodes, Solar Cell, Solar Cell Metamaterial, Solar Cell Molecular Electronics, Solar Energy, Thin Film Solar Cell, transparent OPVs, ultra-narrow bandgap
Category(s): Electrical, Electrical > Electronics & Semiconductors, Materials > Functional Materials, Energy & Environment > Energy Generation > Solar
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