Search Results - yuanyuan+he

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Additive manufacturing platform for customizable drug-releasing IUDs and pharmaceuticals
Using 3D printing to create customizable IUDs that can release multiple drugs in a controlled way, tailored to individual patient needs Background Intrauterine devices (IUDs) are a widely used form of long-acting reversible contraception, valued for their efficacy, low maintenance, and extended duration of action. The field of reproductive healthcare...
Published: 12/5/2025   |   Inventor(s): Mohammed Maniruzzaman, Leela Chakka, Yu Zhang, Gustavo Doncel, Vivek Agrahari, M. Peet
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery
A Linear Actuator Design for Ballistic Projection
Advantages Generates high-speed, high-acceleration motion without rigid springs or levers. Uses soft and flexible materials, reducing material cost and weight. Enables compact actuator designs suited for confined or delicate environments. Provides energy-efficient motion with minimal energy storage requirements. Adaptable for robotics, medical,...
Published: 12/2/2025   |   Inventor(s): Yu Zeng, Stephen Deban
Keywords(s): Medical Devices, Robotics
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Engineering > Mechanical Engineering
B Cell-Based Assay to Expand Antigen-Specific T Cells (UCLA Case No. 2025-288)
UCLA researchers from the Department of Medicine have developed a novel B cell-based assay to expand antigen-specific T cells, allowing for an efficient, patient-specific platform to generate tumor antigen-specific T cells. BACKGROUND: Adoptive T cell therapies have emerged as a promising strategy for cancer immunotherapy, enabling the expansion of...
Published: 11/6/2025   |   Inventor(s): Yuanyuan Tong, Willy Hugo, Maureen Su, Melissa Lechner, Robert Prins
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Task-Oriented Edge Metaverse for Smart Cities and Critical Systems
This invention introduces a task-oriented “Microverse” architecture that creates temporary, edge-based digital twins for 5G/IoT network slices. By combining real-time data fusion, per-task blockchain security, and immersive VR/AR interfaces, it delivers sub-second situational awareness and secure collaboration for smart cities, infrastructure,...
Published: 11/12/2025   |   Inventor(s): Yu Chen, Qian Qu
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Pressure-assisted 3D printing for tunable micro/nanoparticle drug delivery
Background In the realm of drug delivery and biomedical therapies, advanced formulations are essential for improving treatment efficacy, minimizing systemic toxicity, and achieving precise therapeutic targeting. Technologies capable of encapsu­lating and preserving the bioactivity of small molecules, proteins, and live cells are particularly critical...
Published: 11/25/2025   |   Inventor(s): Mohammed Maniruzzaman, Jiawei Wang, Niloofar Aghda, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
IL-2 Independent Ultrahigh Human T Cell Activations Through Biomimetics of Immune Synapses by Graphene Oxides (UCLA Case No. 2021-068)
UCLA researchers in the Department of Materials Science and Engineering have constructed a novel graphene oxide-based platform for robust T cell activation through artificial immune synapse formation. BACKGROUND: T cells are a critical arm of the immune system with tremendous therapeutic value for immune disorders and cancer. However, modulation of...
Published: 10/2/2025   |   Inventor(s): Yu Huang, Lili Yang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Self-Assembling HER2 Nanobody Liposomes: Smarter Cancer Drug Delivery
This invention introduces a one-step self-assembly method that integrates HER2-targeted chimeric nanobodies directly into liposomal membranes, enabling scalable production of immunoliposomes with high drug encapsulation, improved tumor targeting, and reduced manufacturing complexity. Background: HER2-targeted therapies have shown promise for treating...
Published: 11/12/2025   |   Inventor(s): Yuan Wan, Mofizur Rahman
Keywords(s): Technologies
Category(s): Campus > Binghamton University
DARTS: A Drone-Based AI-Powered Real-Time Traffic Incident Detection System
Advantages All-weather reliability with thermal-AI fusion ensuring uninterrupted traffic monitoring. Automated incident verification delivers alerts faster, reducing emergency response times. Privacy-preserving trajectory analysis safeguards driver identity while ensuring roadway safety. Scalable drone deployment eliminates costly infrastructure...
Published: 9/16/2025   |   Inventor(s): Bai Li, Yu Zhang
Keywords(s): Artificial Intelligence, Automotive /Traffic Tech, Optics and Imaging
Category(s): Technology Classifications > Engineering > Drones, Technology Classifications > Computer Science > C/S Transportation, Technology Classifications > Computer Science > Algorithms
SPLICER: Small Molecule-Inducible Gene Expression Switches
Enables Ligand-Inducible Regulation of Gene Expression or Knockdown This small molecule-inducible gene expression based on riboswitches (SPLICER) enables precise, drug-responsive control of gene expression for safer and more flexible gene and cell therapies. In mammalian cells, alternative splicing greatly expands the diversity of RNA sequences. These...
Published: 9/2/2025   |   Inventor(s): Eric Wang, Yu Zhou
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Large-Area Solution-Processed Ionomer-Interlayered Bulk Monolayer MOS2 Membranes With Thickness-Scalable Bright Luminescence and Dual Electron-Ion Transport (Case No. 2025-281)
Summary: UCLA researchers have developed a novel hybrid 2D material platform that significantly improves the utility and optical performance of monolayer molybdenum disulfide (MoS2) by integrating a Nafion interlayer. Background: Monolayer transition metal dichalcogenides (TMDs), particularly MoS2, have shown promise in the fields of optics and...
Published: 9/25/2025   |   Inventor(s): Xiangfeng Duan, Yu Huang, Boxuan Zhou
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Materials > Semiconducting Materials, Materials > Membranes, Materials > Composite Materials, Electrical, Electrical > Flexible Electronics, Electrical > Electronics & Semiconductors, Electrical > Sensors, Chemical, Chemical > Chemical Sensors, Chemical > Polymers
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