Search Results - mohammed+maniruzzaman

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Pharmaceutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Background Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharma­ceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025   |   Inventor(s): Mohammed Maniruzzaman, Vineet Kulkarni, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Enhanced pharmaceutical co-crystal production via continuous dielectric heating and hot melt extrusion method
CoMIDEx uses microwave heating and extrusion to create drug cocrystals, enhancing their solubility and effectiveness. It’s a continuous, eco-friendly process that improves medicine availability without using solvents. Background Pharmaceutical development heavily relies on active pharmaceutical ingredients (APIs) to provide therapeutic benefits....
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Jiaxiang Zhang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
3D printing technology for customized pharmaceutical dosage forms
The invention utilizes 3D printing with selective laser sintering to create pharmaceutical tablets from amorphous solid dispersions, enhancing drug solubility and bioavailability without additional excipients, allowing customizable drug release rates and unique dosage forms. Background In the pharmaceutical industry, the development of drugs with...
Published: 8/28/2024   |   Inventor(s): Mohammed Maniruzzaman, Robert Williams, Daniel Davis, Rishi Thakkar
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic
“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)
Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Anqi Lu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Drug delivery
DosePlus: A pharmaceutical 3D-printing platform for flexible and precise dosages
Problem Innovations in 3D printing have caused a paradigm shift in the design and manufacture of pharmaceuticals. By allowing for on-demand production of custom dosages, 3D printing has the potential to transform the field of personalized medicine and the economics of pharmaceutical manufacturing.1 However, existing 3D printing techniques for drug manufacturing...
Published: 11/1/2023   |   Inventor(s): Mohammed Maniruzzaman, Jiaxiang Zhang, Rishi Thakkar
Keywords(s): 3D printing, Drug development, Pharmaceuticals
Category(s): Life sciences > Therapeutics > Manufacturing platform
Efficient 3D printing manufacturing platform for poorly soluble drugs
Novel 3D printing approach enables single-step manufacturing of poorly soluble drugsBackgroundA large number of pharmaceuticals are eliminated by the body due to their poor water solubility. This limits effectiveness because the drugs cannot be efficiently absorbed. To overcome this, drugs can be administered in an amorphous state rather than a crystalline...
Published: 11/1/2023   |   Inventor(s): Robert Williams, Daniel Davis, Mohammed Maniruzzaman, Rishi Thakkar
Keywords(s): 3D printing, Manufacturing, Pharmaceuticals
Category(s): Life sciences > Therapeutics > Drug delivery