Search Results - mohammed+maniruzzaman

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SMART 3D-printed proliposomes for stable, targeted drug delivery
Background In the realm of drug delivery, particularly for cancer therapeutics, there is a growing demand for robust nanocarrier systems that offer improved targeting, extended shelf-life, and consistent efficacy. Liposomes have historically served as biocompatible delivery vehicles; however, they often suffer from formulation instability and limited...
Published: 5/27/2025   |   Inventor(s): Mohammed Maniruzzaman, Santosh Bashyal, Ishaan Duggal, Muhammad Rahim
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform, Life sciences > Therapeutics > Formulation
Multi-material electrospinning system for 3D-printed fiber architectures
Background Electrospinning and additive manufacturing have become increasingly important in fields such as biotechnology, pharmaceuticals, and tissue engineering, where there is growing demand for complex fiber architectures and multifunctional material systems. However, traditional electrospinning methods struggle to meet the precision, scalability,...
Published: 4/25/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi, Ishaan Duggal
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Mopill: solar-powered mobile 3D printing system for on-demand drug manufacturing
Background Pharmaceutical manufacturing has long relied on centralized, large-scale batch production that demands substantial infrastructure and stable energy sources. However, this model is increasingly ill-suited for the growing need for personalized, rapidly deployable medications, especially in disaster relief zones, rural areas, or low-resource...
Published: 4/25/2025   |   Inventor(s): Mohammed Maniruzzaman, Leela Chakka, Faez Alkadi, Vineet Kulkarni
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Lipid-coated granule feedstock for high-precision pharmaceutical 3D printing
Background The field of pharmaceutical manufacturing is rapidly evolving to meet increasing demands for personalized drug delivery, precise dosage forms, and consistent controlled-release profiles. As healthcare shifts toward individu­alized treatment plans, clinicians and researchers are seeking advanced manufacturing solutions that deliver compact,...
Published: 4/25/2025   |   Inventor(s): Mohammed Maniruzzaman, Bhupendra Giri, Vineet Kulkarni
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Pharmaceutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Background Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharma­ceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 4/29/2025   |   Inventor(s): Mohammed Maniruzzaman, Vineet Kulkarni, Faez Alkadi, Leela Chakka
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 2/20/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Enhanced pharmaceutical co-crystal production via continuous dielectric heating and hot melt extrusion method
CoMIDEx uses microwave heating and extrusion to create drug cocrystals, enhancing their solubility and effectiveness. It’s a continuous, eco-friendly process that improves medicine availability without using solvents. Background Pharmaceutical development heavily relies on active pharmaceutical ingredients (APIs) to provide therapeutic benefits....
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Jiaxiang Zhang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
3D printing technology for customized pharmaceutical dosage forms
The invention utilizes 3D printing with selective laser sintering to create pharmaceutical tablets from amorphous solid dispersions, enhancing drug solubility and bioavailability without additional excipients, allowing customizable drug release rates and unique dosage forms. Background In the pharmaceutical industry, the development of drugs with...
Published: 8/28/2024   |   Inventor(s): Mohammed Maniruzzaman, Robert Williams, Daniel Davis, Rishi Thakkar
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic
“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)
Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Anqi Lu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Drug delivery
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