Search Results - yangfeng+li

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Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 9/12/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Life Science, Medical Devices, Imaging, Acoustics, Women's Health
Fully Human Chimeric Antigen Receptors Against CD276 for the Treatment of Solid Tumors
Summary The National Cancer Institute (NCI) seeks research co-development partners and licensees for a panel of five fully human antibodies against CD276 for the treatment of solid tumors. The collection also includes human CARs incorporating the antibodies for immunotherapeutic use. Description of Technology Chimeric antigen receptor (CAR)-T cell...
Published: 6/9/2025   |   Inventor(s): Brad St. Croix, Pradip Bajgain, Yang Feng
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Immunology, Collaboration Sought > Licensing
Steric Hindrance Effect of Additives for Tuning the Perovskite Crystal Orientation (Case No. 2024-023)
Summary: UCLA Researchers in the Department of Materials Science and Engineering have developed a method to tune perovskite crystal orientation for increased performance, energy efficiency, and reduced material defect with a variety of field applications, including solar cells and LEDs. Background: Perovskite holds considerable promise as a highly...
Published: 2/14/2025   |   Inventor(s): Yang Yang, Chunqing Ma, Haoxiang Duan, Dong Meng
Keywords(s): Energy Efficiency, energy-efficient, Imaging, Liquid-Crystal Display, Nanocrystal, OLED, Optoelectronics, organic photo detector, organic photovoltaics, perovskite, perovskite devices, perovskite solar cell, photodetection, Solar Cell, X-ray detectors
Category(s): Chemical > Chemical Processing & Manufacturing, Energy & Environment > Energy Efficiency, Energy & Environment, Materials > Composite Materials, Optics & Photonics, Optics & Photonics > Fiber Optics, Materials > Functional Materials
An OCT method to improve scleral lens fitting
Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...
Published: 9/4/2025   |   Inventor(s): David Huang, Yan Li, Clara Llorens Quintana
Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Imaging, Software
Group V Doping in Thin Film Solar Cells
The Problem: Cost-effective renewable energy sources are needed more than ever to meet the growing demand for sustainable energy. Cadmium Telluride (CdTe) solar cells are gaining popularity to meet this need due to their relatively low production costs. However, this technology requires doping in order to reach the efficiencies required for commercial...
Published: 10/2/2024   |   Inventor(s): Feng Yan
Keywords(s):  
Category(s): Technology Classifications > Manufacturing, Technology Classifications > Energy
High-Throughput Direct-Measurement of Telomere Length
Telomeres are linear chromosome end-capping repetitive DNA sequences. They serve to protect the ends of chromosomes from undesirable fusion events, thus integrity and length are crucial for stability. Natural attrition as well as mutations can affect telomere integrity and length resulting in chromosome instability, senescence, cell death and human...
Published: 2/13/2025   |   Inventor(s): Julian Chen, Yang Li, Dhenugen Logeswaran
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors
Development of Next Generation Antibody Drug Conjugates (ADCs) Against CD276
Abstract: Angiogenesis is the formation of new blood vessels from pre-existing blood vessels. Angiogenesis occurs during normal growth and development (physiological angiogenesis) and during the growth of solid tumors (pathological angiogenesis). CD276, also known as B7-H3, is a cell surface tumor endothelial marker that is highly expressed in the tumor...
Published: 4/22/2025   |   Inventor(s): Brad St. Croix, Yang Feng, Steven Seaman
Keywords(s): ADC, antibody drug conjugate, B7-H3, CD276, Immunotherapy, Monoclonal Antibody, St. Croix
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Agonistic Human Monoclonal Antibodies against Death Receptor 4 (DR4)
Abstract: The National Cancer Institute is seeking parties interested in licensing human monoclonal antibodies (mAbs) that bind to death receptor 4 ("DR4"). The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its functional receptors, DR4 and DR5, have been recognized as promising targets for cancer treatment.  Therapeutics...
Published: 4/22/2025   |   Inventor(s): Dimiter Dimitrov, Yang Feng
Keywords(s): ANTIBODY, death receptor, Dr4, Mab, TRAIL
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology
Therapeutic antibody-drug conjugates targeting CD56-positive cancers
Abstract: The glycoprotein CD56, also known as a neural cell adhesion molecule (NCAM), plays an important role in normal physiological functions.  It is expressed in low levels in normal cells such as neurons, glia, skeletal muscle and natural killer cells. It is highly expressed on a variety of cancerous cells including those of neuroblastoma, small-cell...
Published: 4/22/2025   |   Inventor(s): Dimiter Dimitrov, Yang Feng, Zhongyu Zhu, John Maris, Robyn Sussman
Keywords(s): ADC, GLYCOPROTEIN, MULTIPLE MYELOMA, Neuroblastoma, pyrrolobenzodiazepine, small-cell lung cancer
Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing
Learning Sparse Features for Self-Supervised Learning with Contrastive Dual Gating
The success of conventional supervised learning relies on large-scale labeled datasets to achieve high accuracy. However, annotating millions of data samples is labor-intensive and time-consuming. This promotes self-supervised learning as an attractive solution with artificial labels being used instead of human-annotated ones for training. Contrastive...
Published: 2/13/2025   |   Inventor(s): Jae-Sun Seo, Jian Meng, Li Yang, Deliang Fan
Keywords(s): Algorithm Development, Machine Learning, Performance Optimization, PS-Computing and Information Technology
Category(s): Computing & Information Technology, Physical Science
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