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nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
Northwestern Startup: Actinia
Founded: 2020 Northwestern Inventor: Mercouri Kanatzidis Weinberg College of Arts and Sciences Department of Chemistry Actinia’s mission is to increase the resolution and decrease the dose used in radiological imaging techniques such as SPECT, CT, and even plain X-rays. Actinia develops cutting-edge radiation detector materials...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s):  
Keywords(s): Startup with Northwestern IP
Category(s): Physical Sciences > Energy & Sustainability, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Healthcare Devices, Tools & IT > Radiology, Physical Sciences > Engineering & Technology, Physical Sciences > Materials and Industrial Processes
Dual-Action Inhibition Strategy for KRAS and LKB1 Mutant NSCLC
NU 2023-113 INVENTORS Lillian Eichner (Feinberg School of Medicine, Department of Biochemistry and Molecular Genetics)* Reuben Shaw (Salk Institute) SHORT DESCRIPTION A dual drug combination to target KRAS and LKB1 mutant non–small cell lung cancer that results in superior efficacy by enhancing T cell recruitment and reducing tumor burden. BACKGROUND Lung...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Reuben Shaw
Keywords(s): Cancer/Oncology, Lung cancer, Repurposed Drugs, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Inhibitors of MNK Kinase for Targeted Cancer and CNS Therapeutics.
NU 2015-098 (NU 2015-098, NU 2018-036, NU 2025-036) INVENTORS Gary Schiltz (Weinberg College of Arts and Sciences, Department of Chemistry)* SHORT DESCRIPTION MNK kinase inhibitors that reduce cancer cell viability and proliferation and penetrates the brain for potential treatment of glioblastoma and CNS disorders. BACKGROUND Leukemia and brain...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, AML - Acute myeloid leukemia, ASD - Autism Spectrum Disorder, Bladder cancer, Brain cancer, Breast cancer, Cancer/Oncology, CNS - Central Nervous System, Colon cancer, Lung cancer, Neurodegenerative disease, Pancreatic cancer, Prostate cancer, Small molecule, Targeted protein degradation, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Use of nucleotide synthesis inhibitors for targeted therapy in MLL3/4 COMPASS mutant cancer
NU 2022-053 INVENTORS Ali Shilatifard (Feinberg School of Medicine, Department of Biochemistry and Molecular Genetics)* Zibo Zhao (Feinberg School of Medicine, Department of Biochemistry and Molecular Genetics)* SHORT DESCRIPTION A therapeutic platform that targets MLL3/4 COMPASS mutant cancers by using nucleotide synthesis inhibitors to disrupt...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s):  
Keywords(s): Bladder cancer, Breast cancer, Cancer/Oncology, Colon cancer, Gastric cancer, Leukemia, Lung cancer, Lymphoma, Prostate cancer, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Molecular Ruler for Quantifying Steady-State and Population Distribution of Photo-Generated Charge Carriers
Provides Quantitative Information on the Steady-State Hot Carriers in Semiconductor and Metal Nanocrystals This DNA-based molecular ruler quantitatively measures the steady-state energy and population distribution of plasmon-generated hot carriers in metal nanocrystals. Photo-generated charge carriers, such as plasmon-generated hot electrons and holes,...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Wei Wei, Yue Hu
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Engineering > Instrumentation-Sensors-Photonics
Conversational Artificial Intelligence for Real-Time, Personalized Health Monitoring
A conversational large language model (LLM) that analyzes health data and communicates with patients to provide actionable insights. Problem: Wearable devices and implantable sensors generate a deluge of continuous data, but clinicians and patients lack efficient tools to translate this information into timely, actionable insights. Existing monitoring...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Brian Litt, Zack Goldblum, Haoer Shi
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Neurology, Software
Category(s): Technology Classifications > Digital Health
Tool to Reduce Intrauterine Device Expulsion in Postpartum Women
Placement device for inserting intrauterine devices (IUD) into the postpartum uterus. Problem: An IUD is a small T-shaped device that is placed into the uterus and provides a highly effective method of long-acting reversible contraception. IUDs can be conveniently placed immediately after delivery to prevent unintended pregnancies. A challenge associated...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Eileen Wang, Gabriel Arenas
Keywords(s): Bioengineering, Women's Health
Category(s): Technology Classifications > Materials, Technology Classifications > Medical Devices
UWB-PostureGuard: A Privacy-Preserving RF Sensing System for Continuous Ergonomic Sitting Posture Monitoring
UWB-PostureGuard is an ergonomic posture monitoring technology that continuously detects sitting posture without cameras or wearable devices, while preserving user privacy. The technology is designed for real-time use in everyday desk and seated work environments, providing posture awareness and enabling timely feedback when sustained or potentially...
Published: 4/28/2026   |   Updated: 4/28/2026   |   Inventor(s): Haotang Li, Zhenyu Qi, Sen He, Kebin Peng, Sheng Tan, Yili Ren, Tomas Cerny, Jiyue Zhao, Zi Wang
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Human Machine Interface, Technology Classifications > Healthcare Portfolios, Technology Classifications > Imaging & Optics > Sensors and Detection > Remote Sensing
Integrated Planning for Safer, Smarter Autonomous Urban Driving
This technology enables autonomous vehicles to plan high-level tasks and low-level motions in a unified, adaptive framework. By continuously sharing safety and efficiency information between planning layers, vehicles can make smarter decisions in complex, unpredictable urban environments. The result is safer navigation without sacrificing operational...
Published: 4/28/2026   |   Updated: 4/28/2026   |   Inventor(s): Shiqi Zhang, Yan Ding
Keywords(s): CleanTech
Category(s): Campus > Binghamton University, Technology Classifications > Engineering
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