Search Results - therapeutics+%3e+gastroenterology

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Dissecting Microbiota-Gut-Brain Interactions for the Anti-Seizure Effects of the Ketogenic Diet (UCLA Case No. 2025-006)
UCLA researchers from the Department of Integrative Biology & Physiology have identified specific components of ketogenic diets that alter the microbiome and improve seizure resistance, providing valuable data to optimize diet treatments for refractory epilepsy. BACKGROUND: Refractory epilepsy, a disease characterized by uncontrolled seizures,...
Published: 9/19/2024   |   Inventor(s): Elaine Hsiao
Keywords(s): diet, dietary fiber, Epilepsy, gut, gut-brain axis, ketogenic diet, microbiome, pediatrics, seizure
Category(s): Therapeutics > Gastroenterology, Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology
Surgical Mesh Permanent Implant (Case No. 2023-109)
Summary: UCLA Researchers in the Department of Chemistry and Biochemistry have developed a bacterial nanocellulose (BNC) that exhibits promising biocompatibility and mechanical properties that can be used as a long-term treatment for medical conditions requiring surgical mesh devices. Background: Surgical mesh devices are medical devices used to...
Published: 8/23/2024   |   Inventor(s): Paul Weiss, Melina Mastrodimos, Maryam Badv
Keywords(s): Biologic Medical Product, Biomedical Engineering, biomedical implantation, Implant (Medicine), Medical Device, Medical Devices and Materials, Orthopedics and Prosthetics (O & P), Prosthesis, Prosthetics, Smart medical device, Surgical Instrument, surgical mesh, Surgical Tools, wearable medical device
Category(s): Medical Devices, Medical Devices > Surgical Tools, Materials, Materials > Functional Materials, Therapeutics, Therapeutics > Gastroenterology, Therapeutics > Urology, Therapeutics > Transplant
SYNERGISM BETWEEN PROTON PUMP INHIBITORS AND A GI PEPTIDE IN REDUCING ACID SECRETION
Case 2000-093UCLA researchers in the Department of Medicine have discovered a novel method to improve the efficacy of proton pump inhibition. BACKGROUND:A vast number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease,...
Published: 7/19/2023   |   Inventor(s): Joseph Pisegna
Keywords(s): Gastroenterology & Digestive Disease, Renal, Therapeutics & Vaccines
Category(s): Therapeutics > Gastroenterology, Therapeutics > Renal
2013-778 MicroRNA Biomarkers and Therapeutic Targets for Colon Cancer and IBD
Summary Researchers at the UCLA Geffen School of Medicine have identified a novel set of biomarkers consisting of a microRNA and aftiphilin (AFTPH) as an effective means to distinguish between tissues with colon cancer and normal tissues. Other biomarkers within the set are linked specifically with inflammatory bowel disease. Background Colon cancer...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics > Gastroenterology
2019-519 MICROBIOME-BASED MODULATION OF SENSORY NEURONAL ACTIVITY
UCLA researchers in the Department of Integrative Biology and Physiology have begun to elucidate the molecular pathways for communication between the gut microbiota and the brain, serving as potential therapeutic targets for the treatment of various neurological diseases.BACKGROUND: The gut microbiota is recognized as an important regulator of brain...
Published: 7/16/2024   |   Inventor(s): Elaine Hsiao
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease
Category(s): Therapeutics > Gastroenterology
2019-520 MATERNAL GUT MICROBIOTA REGULATION OF NEURODEVELOPMENT AND ADULT SENSORY BEHAVIOR
UCLA Researchers in the Department of Integrative Biology and Physiology have determined the necessary role for maternal gut microbes in neurodevelopment and that select microbes may prevent abnormal neurodevelopmental phenotypes.BACKGROUND: The gastrointestinal tract and brain are intimately linked, and in the past decade there have been increasing...
Published: 2/16/2024   |   Inventor(s): Elaine Hsiao, Helen Vuong
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease
Category(s): Therapeutics > Gastroenterology
2000-093 Novel Diuretic and Inhibitor of Gastric Acid Secretion
Background A wide number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease, duodenalulcers, atrophic gastritis, esophagitis, and the like. Conditions such as ZES and peptic ulcers, in particular, can have serious complications...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics > Gastroenterology
2018-920 INTRA-PROCEDURE IMAGE-BASED FLOW QUANTIFICATION (FOR TREATMENT EVALUATION)
INTRODUCTION:UCLA researchers in the Department of Radiology have developed a new method for analyzing portal vein blood blow at transjugular intrahepatic portosystemic shunt (TIPS) creation.BACKGROUND:TIPS creation is a common interventional method for the treatment of portal hypertension. However, post-procedure complications can arise, which often...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease, Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools > Research Methods, Therapeutics > Gastroenterology
A Wearable Platform for In-Situ Analysis of Hormones
UC Case No. 2018-657SUMMARY:UCLA researchers in the Department of Electrical and Computer Engineering have developed a highly sensitive, wearable hormone monitoring platform.BACKGROUND:Biofluid levels provide insight for monitoring depression, reproduction, and stress. Invasive methods are used to detect low-concentration biofluids. However, realizing...
Published: 7/19/2023   |   Inventor(s): Sam Emaminejad, Sanaz Pilehvar
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Endocrinology, Gastroenterology & Digestive Disease, Life Science Research Tools, Medical Devices and Materials, Psychiatry / Mental Health
Category(s): Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology, Therapeutics > Psychiatry And Mental Health
2019-463 PREVENTION OF THE LATE COMPLICATIONS OF ACUTE PANCREATITIS
SummaryUCLA researchers in the Department of Medicine and Surgery have developed a novel therapeutic for the prevention of late inflammatory complications in severe acute pancreatitis patients.BackgroundAcute pancreatitis, or sudden inflammation of the pancreas, a disease generally caused by gallstones or alcohol abuse, is a common reason for hospitalization...
Published: 7/19/2023   |   Inventor(s): Jonathan Kaunitz, Yasutada Akiba
Keywords(s): Endocrinology, Gastroenterology & Digestive Disease, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
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