Search Results - therapeutics+%3e+gastroenterology

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Adaptable Abdominal Binder (Case No. 2026-022)
Summary: A UCLA researcher in the Department of Rehabilitation Services has developed a versatile medical garment designed to support the abdomen, relieve patient discomfort, and accommodate various post-operative medical devices. Background: Following abdominal surgeries and related medical procedures, it is essential to properly secure the abdomen...
Published: 6/8/2026   |   Updated: 6/8/2026   |   Inventor(s): Esau Baqi
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Surgical Tools, Medical Devices > Hospital Systems, Materials, Materials > Functional Materials, Therapeutics, Therapeutics > Gastroenterology
Microbial Regulation of Immune Tolerance and Risk for Cancer (UCLA Case No. 2026-153)
UCLA researchers in the Department of Integrative Biology and Physiology have identified a microbiome-driven signaling pathway that increases serotonin production and colorectal cancer (CRC) risk which may serve as a valuable therapeutic target for CRC. BACKGROUND: The gut microbiome plays a central role in regulating host physiology through interactions...
Published: 5/22/2026   |   Updated: 3/4/2026   |   Inventor(s): Elaine Hsiao, Lewis Yu
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Gastroenterology, Therapeutics > Immunology And Immunotherapy, Diagnostic Markers > Cancer
Food Derived Compounds for Improving Cognitive Health (UCLA Case No. 2025-279)
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Published: 6/11/2026   |   Updated: 9/18/2025   |   Inventor(s): Arpana Church, Jennifer Labus
Keywords(s):  
Category(s): Therapeutics > Metabolism And Endocrinology, Therapeutics > Gastroenterology
Compositions and Methods for Boosting Stress, Psychological, and Cognitive Related Resilience (UCLA Case No. 2024-281)
UCLA researchers have identified a novel high resilience brain gut microbiome phenotype and biological pathways by which stress related disorders may be prevented or reduced. BACKGROUND: In the United States, stress-related health care costs and lost productivity exceed $300 billion annually, underscoring the urgent need to improve resilience: the...
Published: 12/16/2025   |   Updated: 9/16/2025   |   Inventor(s): Arpana Church, Tien Dong
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
DNA Methylation-Based Algorithm to Diagnose Irritable Bowel Syndrome and Other GI Conditions (UCLA Case No. 2022-229)
UCLA researchers in the Department of Gastroenterology have developed a DNA methylation-based algorithm to diagnose irritable bowel syndrome and other GI conditions. Blood-based genome-wide DNA methylation profiles have been utilized to develop a reliable test to diagnose irritable bowel syndrome (IBS) versus inflammatory bowel disease (IBD), celiac...
Published: 9/11/2025   |   Updated: 9/11/2025   |   Inventor(s): Lin Chang, Swapna Joshi
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Platforms > Diagnostic Platform Technologies
Targeting the Bile Acid Pathway to Treat Cardiometabolic Disease (UCLA Case No. 2024-146)
UCLA researchers from the Department of Medicine and Division of Cardiology have identified target enzymes involved in bile acid synthesis and developed methods to improve disease outcomes in fatty liver and atherosclerosis. BACKGROUND: Dietary fat is an essential, energy-dense nutrient necessary for survival. To support this, the intestinal system...
Published: 7/17/2025   |   Updated: 7/8/2025   |   Inventor(s): Thomas Vallim
Keywords(s):  
Category(s): Life Science Research Tools > Screening Libraries, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology, Life Science Research Tools > Research Methods, Therapeutics > Cardiovascular
Ingestible Device for Medical Interaction With the Gastrointestinal Tract and Surrounding Tissues (Case No. 2024-226)
Summary: UCLA researchers have conceptualized an ingestible, self-powered, and wireless capsule that can be used to effectively diagnose and treat gastrointestinal disorders. Background: Gastrointestinal (GI) disorders, including conditions like irritable bowel syndrome, Crohn’s disease, and gastroparesis, impact millions of people worldwide...
Published: 8/12/2025   |   Updated: 6/27/2025   |   Inventor(s): Wentai Liu, Ryan Kochis, Brian Arianpour, Alejandro Miron Jabalera
Keywords(s): Biosensor, brain-gut microbiome, Gastroenterology, Gastroenterology & Digestive Disease, gastrointestinal (GI) tract diseases, gut inflammation, Human Gastrointestinal Tract, minimally invasive device, Neuromodulation, wireless capsule endoscopy
Category(s): Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Gastroenterology, Software & Algorithms > Digital Health, Medical Devices > Monitoring And Recording Systems, Mechanical > Sensors, Chemical > Chemical Sensors, Life Science Research Tools > Screening Libraries
Gut Bacterial Detoxification of Methylmercury (UCLA Case No. 2023-188)
UCLA researchers from the Department of Integrative Biology and Physiology have developed a microbiome-based therapy for methylmercury detoxification, leveraging a genetically engineered probiotic that neutralizes methlymercury in the gut prior to systemic absorption with potential applications in acute detoxification, preventative healthcare, and environmental...
Published: 8/15/2025   |   Updated: 6/24/2025   |   Inventor(s): Elaine Hsiao
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
Manipulating the Gut Microbiome To Modify Host Eating Behavior (UCLA Case No. 2024-181)
UCLA researchers from the Department of Integrative Biology & Physiology have identified aspects of gut microbiome metabolism that affect host eating behavior, leading to possible microbiome therapies for appetite regulation. BACKGROUND: The microbiome consists of all microbes within the human body and has recently been shown to influence human...
Published: 7/17/2025   |   Updated: 2/26/2025   |   Inventor(s): Elaine Hsiao
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology
Microbial Metabolites for Promoting Brain Health (UCLA Case No. 2024-196)
UCLA researchers in the Department of Integrative Biology and Physiology have developed a maternal supplementation with microbiome-dependent metabolites to promote growth and neurobehavioral health in children impacted by maternal protein undernutrition. BACKGROUND: Protein undernutrition poses a significant risk of childhood stunting, accompanying...
Published: 7/17/2025   |   Updated: 12/12/2024   |   Inventor(s): Elaine Hsiao
Keywords(s): Brain, brain health, growth defects, malnutrition, maternal supplementation, microbial metabolites, microbiome, neurobehavioral impairment, neurodevelopment, nutrition, protein undernutrition, stunting
Category(s): Therapeutics > CNS and Neurology, Therapeutics > Gastroenterology, Therapeutics > Psychiatry And Mental Health
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