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Proximity Algorithms for ECT Reconstruction
Enables high-quality emission computers tomography (ECT) whild reducing the patient's radiation exposure. BackgroundEmission computed tomography (ECT) is an important scientific and medical imaging technique. Clinical applications of ECT include detecting, staging and monitoring response to cancer therapy; detection and risk stratification of...
Published: 5/13/2025   |   Inventor(s): Andrzej Krol, Yuesheng Xu, Si Li, Lixin Shen
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Medical Imaging
All Temp. Rechargeable Solid State Lithium Batteries
THE CHALLENGE The challenge in advancing lithium metal batteries lies in developing solid electrolytes that not only perform reliably but also meet market demands for safety, durability, and scalability. Current materials—such as liquid electrolytes and polymer gels—either pose serious safety risks like leakage and flammability or degrade...
Published: 4/16/2025   |   Inventor(s): Louis Madsen, Feng Lin, Deyang Yu
Keywords(s):  
Category(s): Technology Classifications > Energy
Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 5/30/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
Silicon-CdTe-Halide Perovskite Triple-Junction Solar Cell
Background Solar energy is one of the most abundant and affordable energies in the world. However, converting solar energy into electricity significantly relies on the power conversion efficiency of the solar cell’s technology. Due to the current limitations of the various materials and physics in the solar cell’s technology, it is a great...
Published: 2/28/2025   |   Inventor(s): Feng Yan, Yanfa Yan
Keywords(s):  
Category(s): Energy & Power, Advanced Materials/Nanotechnology, Physical Science
Novel cermet composite for nuclear waste immobilization
​ 1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...
Published: 5/22/2025   |   Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso
Keywords(s):  
Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
Advanced hot melt extrusion (HME) technology with reduced decomposition
The technology involves using hot melt extrusion (HME) to prepare amorphous drug formulations with reduced decomposition. This method incorporates a pharmaceutically acceptable thermoplastic polymer and an organic solvent to lower processing temperatures and stress, ensuring drug stability. Background HME is a widely used technique in the pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Feng Zhang, Robert Williams, Abbe Miller, Siyuan Huang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug discovery, Life sciences > Biomaterials
The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses
Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon...
Published: 9/6/2024   |   Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen
Keywords(s): Biomedical, Human Health, Pharma, Research, Veterinary Medicine
Category(s): Biotechnology, Biomedical, Pharma, Veterinary Medicine
Inhaled formulations of the NSAID indomethacin
Background Patients suffering from headache and migraine have a limited list of thera­peutic options that often is shortened by issues stemming from tolerability or efficacy. For this reason, there is a big push in the industry to develop inhaled treatments for these disorders. The invention described here repurposes a compound with known efficacy...
Published: 5/8/2024   |   Inventor(s): Hugh Smyth, Feng Zhang, Jamie Spahn
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Manufacturing platform
Simulation-based Real-time Production Control
In many production systems like semiconductor manufacturing, food industry, and battery production, the amount of time a part can spend in successive buffers is limited in many production systems because of possible quality concerns. If a part's residence time exceeds these limits, it must be trashed, which results in waste and lost output. To prevent...
Published: 2/13/2025   |   Inventor(s): Feng Ju, Feifan Wang
Keywords(s): Algorithm Development, Machine Learning, Manufacturing, PS-Manufacturing,Construction,Mechanical, Real-Time System
Category(s): Manufacturing/Construction/Mechanical, Physical Science, Computing & Information Technology
Machine Learning Algorithm for Inferring User Activities from IoT Device Events
The ubiquitous and heterogeneous deployment of internet of things (IoT) devices in smart homes has created new opportunities to extract knowledge, awareness, and intelligence via monitoring and understanding the devices’ interactions with their environments and users. Meaningful information from network traffic of IoT devices in smart homes can...
Published: 2/13/2025   |   Inventor(s): Guoliang Xue, Yinxin Wan, Kuai Xu, Feng Wang, Xuanli Lin
Keywords(s): Algorithm Development, Internet of Things, Machine Learning, Networks, IT, Software and Communication, PS-Computing and Information Technology, PS-Wireless and Networking, Security
Category(s): Computing & Information Technology, Physical Science, Wireless & Networking
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