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Advanced hot melt extrusion (HME) technology with reduced decomposition
The technology involves using hot melt extrusion (HME) to prepare amorphous drug formulations with reduced decomposition. This method incorporates a pharmaceutically acceptable thermoplastic polymer and an organic solvent to lower processing temperatures and stress, ensuring drug stability. Background HME is a widely used technique in the pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Feng Zhang, Robert Williams, Abbe Miller, Siyuan Huang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug discovery, Life sciences > Biomaterials
The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses
Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon...
Published: 9/6/2024   |   Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen
Keywords(s): Biomedical, Human Health, Pharma, Research, Veterinary Medicine
Category(s): Biotechnology, Biomedical, Pharma, Veterinary Medicine
Inhaled formulations of the NSAID indomethacin
Background Patients suffering from headache and migraine have a limited list of thera­peutic options that often is shortened by issues stemming from tolerability or efficacy. For this reason, there is a big push in the industry to develop inhaled treatments for these disorders. The invention described here repurposes a compound with known efficacy...
Published: 5/8/2024   |   Inventor(s): Hugh Smyth, Feng Zhang, Jamie Spahn
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Manufacturing platform
Simulation-based Real-time Production Control
In many production systems like semiconductor manufacturing, food industry, and battery production, the amount of time a part can spend in successive buffers is limited in many production systems because of possible quality concerns. If a part's residence time exceeds these limits, it must be trashed, which results in waste and lost output. To prevent...
Published: 6/5/2024   |   Inventor(s): Feng Ju, Feifan Wang
Keywords(s): Algorithm Development, Machine Learning, Manufacturing, PS-Manufacturing,Construction,Mechanical, Real-Time System
Category(s): Manufacturing/Construction/Mechanical, Physical Science, Computing & Information Technology
Machine Learning Algorithm for Inferring User Activities from IoT Device Events
The ubiquitous and heterogeneous deployment of internet of things (IoT) devices in smart homes has created new opportunities to extract knowledge, awareness, and intelligence via monitoring and understanding the devices’ interactions with their environments and users. Meaningful information from network traffic of IoT devices in smart homes can...
Published: 2/14/2024   |   Inventor(s): Guoliang Xue, Yinxin Wan, Kuai Xu, Feng Wang, Xuanli Lin
Keywords(s): Algorithm Development, Internet of Things, Machine Learning, Networks, IT, Software and Communication, PS-Computing and Information Technology, PS-Wireless and Networking, Security
Category(s): Computing & Information Technology, Physical Science, Wireless & Networking
An Automatic Configuration Method for Testing Integrated Circuits Independent of Chip Package Configuration
­Advantages: Automated testing assures consistent reliability in integrated circuits, meeting stringent industry standards. System efficiency is heightened by omitting external circuits, reducing overall setup time. Adaptable technology accommodates diverse chip configurations, seamlessly handling varied power and data. Summary: In the rapidly...
Published: 8/16/2024   |   Inventor(s): Cong Xu, Yunghsiao (Steven) Chung, Feng Yu, Liwei Xu, Stephen Saddow
Keywords(s): Electronics, Sensors
Category(s): Technology Classifications > Electronics > Electronics Sensors, Technology Classifications > Engineering > Electrical Engineering, Technology Classifications > Engineering > Manufacturing
Electronic Component Authenticity Via Electrical Signal Analysis Using Artificial Intelligence with Deep Learning
­Advantages: Swiftly authenticates ICs, ensuring quick and reliable verification for secure electronic component procurement. Ensures accurate IC authentication with high efficiency through matrix scan and deep learning model. Significantly reduces counterfeit IC risks by creating an 'electronic signature,' ensuring comprehensive risk...
Published: 8/16/2024   |   Inventor(s): Yunghsiao (Steven) Chung, Feng Yu, Stephen Saddow, Junjie Xiong
Keywords(s): Artificial Intelligence, Electronics, Machine Learning
Category(s): Technology Classifications > Engineering > Electrical Engineering, Technology Classifications > Engineering > Manufacturing, Technology Classifications > Electronics > Electronics Sensors
Battery Electrode and Materials Recycling by Rapid High-temperature Heating
Challenge ­Recycling end-of-life Lithium-ion batteries (LIB) for second use applications is an effective strategy to secure the supply chain of battery materials. Current commercial LIB recycling methods, including hydrometallurgical and pyrometallurgical processes, primarily aim to recover the valuable metals such as Li, Co, Ni, and Mn from the...
Published: 6/6/2024   |   Inventor(s): Feng Lin, Lei Tao, Liangbing Hu, Xizheng Wang, Tangyuan Li
Keywords(s):  
Category(s): Technology Classifications > Energy, Technology Classifications > Electronics
Algorithm for Inferring User Activities from IoT Network Traffic
Recently, the surge in Internet-of-things (IoT) device deployment within smart homes has led to a large need for understanding user activities through the vast data generated by these devices. While studies have explored individual device behaviors and network traffic patterns, there remains a gap in leveraging this data collectively to infer and monitor...
Published: 11/22/2023   |   Inventor(s): Guoliang Xue, Yinxin Wan, Kuai Xu, Feng Wang
Keywords(s): Algorithm Development, Internet of Things, Networks, IT, Software and Communication, PS-Computing and Information Technology, PS-Wireless and Networking, Security
Category(s): Computing & Information Technology, Physical Science, Wireless & Networking
High-energy Lithium Batteries
THE CHALLENGE Lithium ion batteries are utilized as power sources in a wide range of applications due to their high energy density capabilities. They are the ideal power source for today’s electric and hybrid electric vehicles. Much of the future of renewable energy will be shaped by the evolution of lithium ion batteries and the industry is...
Published: 11/1/2023   |   Inventor(s): Feng Lin, James Steiner
Keywords(s):  
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications > Energy, Technology Classifications > Transportation, Technology Classifications > Environment/Green Tech
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