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Search Results - shuai+wang
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YTH Domain-Containing Family Protein 1 (YTHDF1): A Novel Therapeutic Target for Alzheimer’s Disease
Advantages: A novel method for targeting m6A methylation via YTHDF1 offers a potential therapy for tauopathies and Alzheimer’s disease YTHDF1 reduces neuroinflammation in Alzheimer’s disease by downregulating pro-inflammatory genes like Ccl6 and Cst7 Enhance working memory and reduce hyperactivity in tauopathy, suggesting cognitive...
Published: 3/6/2025
|
Inventor(s):
Gopal Thinakaran
,
Shuai Wang
Keywords(s):
Animal Models
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics
Resveratrol and Quercetin-Loaded Nanoparticles
Obesity and related metabolic diseases are a significant public health issue in the US and worldwide. Studies have shown that pathologically expanded white adipose tissue is associated with multiple obesity-related comorbidities including diabetes, cardiovascular disease as well as certain types of cancer. Current strategies to combat obesity and metabolic...
Published: 2/13/2025
|
Inventor(s):
Shu Wang
,
Fang Zhou
,
Corrie Whisner
,
Zhaoyang Fan
Keywords(s):
Category(s):
Nutraceuticals/Extracts
,
Advanced Materials/Nanotechnology
,
Life Science (All LS Techs)
,
Non-Cancer Therapeutics
Nanoencapsulation of Forskolin for Combatting Obesity
Obesity and related metabolic diseases are increasing in prevalence in the US and worldwide. Pathologically expanded white adipose tissue (WAT) has been associated with multiple obesity-related comorbidities including diabetes, cardiovascular disease, cancers and more. Lifestyle intervention, pharmacotherapy, and various surgical procedures are used...
Published: 2/13/2025
|
Inventor(s):
Shu Wang
,
Zhaoyang Fan
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Life Science (All LS Techs)
,
Pharmaceuticals
,
Non-Cancer Therapeutics
,
Nutraceuticals/Extracts
Hydrogen Sulfide Releasing Agents
Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 10/8/2024
|
Inventor(s):
Ming Xian
,
Hua Wang
,
Yu Zhao
Keywords(s):
Chemistry
Category(s):
Technologies > Health & Well-being > Chemistry
,
Technologies > Health & Well-being > Pharmaceutical
Functionalized Bacterial Cellulose Nanofiber-Based Battery Separators
Background Lithium metal batteries (LMBs), including lithium sulfur batteries (LSBs), use lithium metal as the anode instead of the conventional graphite anode used in lithium-ion batteries (LIBs), and can deliver an energy density that is significantly higher than LIBs. In LMBs, the cathode can be the conventional cathode materials used in LIBs, or...
Published: 2/13/2025
|
Inventor(s):
Zhaoyang Fan
,
Wenyue Li
,
Shu Wang
Keywords(s):
Category(s):
Biomaterials
,
Physical Science
,
Energy & Power
,
Alternative Energy/Biofuels/Bioplastics/Algae
Multifunctional Edible Nutraceutical Coating
The short shelf life of fresh produce, due in large part to microbial induced spoilage, is a serious problem that is costing the food industry billions a year. Many plants have natural phytochemicals which help confer resistance to microbial infections. Phytochemicals also have health benefits for humans, making them attractive candidates for coating...
Published: 2/13/2025
|
Inventor(s):
Shu Wang
,
Zhaoyang Fan
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Advanced Materials/Nanotechnology
Lithium selective organogels
Background Lithium (Li) is a highly reactive alkali metal with excellent heat and electrical conductivity properties, making it useful for a variety of industrial applications. Because of Li’s high reactivity, pure elemental Li is not found in nature but is present as a constituent of salts or other compounds found in brines, mineral ores, clays,...
Published: 12/11/2023
|
Inventor(s):
Jonathan Sessler
,
Zachariah Page
,
Hu Wang
Keywords(s):
Category(s):
Physical sciences > Materials
,
Physical sciences > Energy > Renewable
,
Life sciences > Research tools > Tool/assay/screening platform
,
Physical sciences > Energy > Battery or electrochemical
Brain Targeted Nanoparticles for Therapeutic Delivery
Because the blood brain barrier (BBB) is a highly selective semipermeable complex, only about 2% of small molecules in the blood can penetrate it; most require transporters on the BBB. While this prevents many toxins, pathogens and other dangerous substances from crossing the BBB, it also makes it difficult to effectively treat various diseases including...
Published: 2/13/2025
|
Inventor(s):
Shu Wang
,
Zhaoyang Fan
Keywords(s):
Category(s):
Advanced Materials/Nanotechnology
,
Biomaterials
,
Cancer Therapeutics
,
Diagnostic Assays/Devices
,
Medical Diagnostics/Sensors
,
Medical Imaging
,
Neurodegenerative Disease Technologies
,
Non-Cancer Therapeutics
,
Pharmaceuticals
,
Life Science (All LS Techs)
Signal Processing Method For Extracting Low Frequency Sounds From Noisy Environments
One of the greatest challenges to speech recognition is accurately filtering speech from noisy backgrounds. Current techniques for noise reduction are robust against random acoustic environments, however, the average microphone tends to attenuate low frequencies and that attenuation is only exacerbated by noise. Because of the ear’s anatomy, current...
Published: 2/23/2023
|
Inventor(s):
Xuan Zhong
,
Shuai Wang
,
Michael Dorman
,
William Yost
Keywords(s):
Medical Devices and Imaging
,
Networks, IT, Software and Communication
Category(s):
Medical Devices