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Controlled Expression and Assembly of Human Group-C Rotavirus-like Particles for Creation of Rotavirus Diagnostic Assays and Improved Vaccine Formulations
CDC researchers have developed methods of producing unlimited quantities of Group-C (GpC) rotavirus antigens. GpC rotaviruses are a major, worldwide cause of acute gastroenteritis in children and adults that is distinct from Group-A rotavirus. However, GpC rotaviruses cannot be grown in culture, resulting in a lack of tools for detection and treatment...
Published: 7/25/2024   |   Inventor(s): Baoming Jiang
Keywords(s): C, CDC Docket Import, CDC Docket Import CDC Prosecuting, CHILDHOOD, Children, DA4BXX, DA4XXX, DAXXXX, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DXXXXX, GROUP, Human, NEONATAL, Neonates, OID-NCIRD-DVD, PARTICLES, rotavirus, Their, THEREOF, viral, Viral-Like, virus, VLXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, ResearchProducts > Antibodies, TherapeuticArea > Cardiology, Application > Research Materials, Application > Occupational Safety and Health, Application > Vaccines, TherapeuticArea > Endocrinology, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Dental
Human Rotavirus Strains and Vaccines for Neonatal Childhood Protection
This invention relates to rotavirus vaccine compositions and methods of vaccination. Rotaviral infection is the most commonly occurring gastrointestinal illness of children world, affecting both developed and developing economies. Additionally, rotavirus infections can affect livestock (especially calves and piglets), and resulting mortality/morbidity...
Published: 7/25/2024   |   Inventor(s): Roger Glass, Yuhuan Wang, Jon Gentsch, Baoming Jiang
Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, CHILDHOOD, Children, DB4BXX, DB4XXX, DBXXXX, DC5BXX, DC5XXX, DCXXXX, DEVELOPED, DEVELOPING, DIARRHEA, DXXXXX, Dysentery, GASTRIC, gastrointestinal, Human, Livestock, NEONATAL, Neonates, OID-NCIRD-DVD, rotavirus, Strain, STRAINS, Vaccine, VETERINARY, VETERINARY vaccine, viral, virus, VLXXXX, VOXXXX, WIXXXX, WJXXXX, WMXXXX, XEXXXX, XHXXXX, YBXXXX, YCXXXX, Zoo, Zoonotic
Category(s): Collaboration Sought > Licensing, Application > Research Materials, ResearchProducts > Research Equipment, Application > Vaccines, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease
Photoreactor for Treatment of Jaundice
Technology Description Oregon State University is seeking a licensee or research collaborator for development or commercialization of a microfluidic visible light photoreactor for the treatment of jaundice in neonatal patients. The device enables safe extracorporeal blood treatment, making it an excellent replacement for equally effective, yet risky,...
Published: 1/16/2023   |   Inventor(s): John Lahmann, Adam Higgins
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Bilirubin, Blood, hyperbilirubinemia, light, Medical Science & Technologies, Neonatal, Newborn, Photoreactor, Sepsis, treatment
Category(s): Medical Devices, Therapeutics, Engineering