Search Results - qianxuan+wang

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Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications

Reference #: 1685 The University of South Carolina is offering licensing opportunities for Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications. Background: Bioconjugation techniques play an important role in modern chemical biology and biomedical sciences, such as protein drug stabilization, target...

Published: 6/12/2024 | Inventor(s): Qian Wang, Shan Hu

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Enzyme Immobilization on Delignified Bamboo Scaffolds as a Multienzyme Bioreactor

Reference #: 01643 The University of South Carolina is offering licensing opportunities for Enzyme Immobilization on Delignified Bamboo Scaffolds as a Multienzyme Bioreactor. Background: Enzymes are used in a multitude of industries as catalysts for production. Though enzymes have many advantages they can often be more costly than other catalyst...

Published: 9/16/2024 | Inventor(s): Qian Wang

Keywords(s):

Category(s): Chemistry and Biochemistry

Therapeutic Inhibition of Molecular Drivers of Microglial Reactivity in Neurodegenerative Disease

It is estimated that over 55 million people have Alzheimer’s disease (AD) or other dementias, and despite their rapidly increasing burden, thus far there are no disease modifying therapeutics available. Novel therapeutic strategies are urgently needed to address the prevention and treatment of AD. Mounting evidence from large scale genetic studies...

Published: 2/14/2024 | Inventor(s): Benjamin Readhead, Qi Wang, Diego Mastroeni, Eric Reiman

Keywords(s):

Category(s): Life Science (All LS Techs), Neurodegenerative Disease Technologies

Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration

Abstract: Retinal degeneration is a deteriorative condition of the human retina caused by the progressive and eventual death of photoreceptor cells. To date, no effective treatment for genetically inherited or age-associated retinal degeneration, which includes a large patient population worldwide, is available. Researchers at the National Eye Institute...

Published: 4/8/2024 | Inventor(s): Wai Wong, Lian Zhao, Xu Wang, Wenxin Ma

Keywords(s): Age-Related Degeneration, AMD, Estrogen-receptor, Microglial Inhibition, National Eye Institute, NEI, Photoreceptor, Retinal degeneration, Retinitis Pigmentosa, RP

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, Collaboration Sought > Collaboration

Telodendrimer Nanoparticles for Protein Delivery

A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics. Background: Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...

Published: 7/24/2023 | Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall

Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers

Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology

Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosing

Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosinghttps://sites.google.com/slu.edu/intellectualproperty/2017/17-036

Published: 1/24/2022 | Inventor(s): Marvin Meyers, Cynthia Dowd, Xu Wang, Robert Brothers, Audrey John, Rachel Edwards

Keywords(s):

Category(s): Therapeutics

A Nanopore Method for Identifying Single Amino Acid in Oligopeptides

Reference #: 01471 The University of South Carolina is offering licensing opportunities for A Nanopore Method for Identifying Single Amino Acid in Oligopeptides Background: The primary sequence of a protein or a peptide is essential to its identification and function. In the area of personalized diagnosis and therapeutics, an accurate proteomic information...

Published: 4/18/2024 | Inventor(s): Chang Liu, Qian Wang

Keywords(s): amino acid, derivatization, identification, nanopore, proteomics

Category(s): Chemistry and Biochemistry, Nanotechnology, Health Sciences

Porous Nanostructures and Methods of Fabrication

Porous Nanostructures and Methods of Fabrication Need: A porous structure may be a selective barrier comprised of inorganic and/or organic materials with varying dimensions and pore sizes. The global demand for some of the subject structures was estimated to be approximately USD$ 18.4 billion in 2014. Driven by the new developments and innovations...

Published: 8/13/2020 | Inventor(s): Xuan Wang

Keywords(s):

Category(s): Materials, Engineering, Nanoparticles

Mechanical Metamaterials for Ultra-Low Frequency Vibration Isolation

Background Vibration is one of the main causes of performance degradation of precision instruments, vibration noise, failure of structural parts, and human discomfort. In particular, the human body is most sensitive to vibrations in low frequency range especially for the wounded and newborn babies in transit. Thus, effective low-frequency vibration...

Published: 2/23/2023 | Inventor(s): Hanqing Jiang, Lingling Wu, Yong Wang, Qianxuan Wang

Keywords(s): Mechanical and Manufacturing

Category(s): Physical Science, Manufacturing/Construction/Mechanical

New Genetic Target for the Treatment of Parkinson’s Disease

Thank you for your interest in this technology. Please see our technology brief here: https://app.in-part.com/articles/RQx7n6BR7ZeM

Published: 10/6/2023 | Inventor(s): Bin Zhang, Zhenyu Yue, Qian Wang, Minghui Wang

Keywords(s):

Category(s): Therapeutic, Target

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