Search Results - protect

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Novel VAR2CSA Immunogens and Methods of Use Thereof
The invention provides immunogen polypeptides comprising fragments of VAR2CSA protein expressed by P. falciparum as potential second-generation placental malaria vaccine candidates. VAR2CSA is the leading antigen target for a placental malaria vaccine, where associated antibody titers are correlated with protection. Aspects of the inventive immunogen...
Published: 10/28/2024   |   Inventor(s): Rui Ma, Niraj Tolia
Keywords(s): Against, CANCER, COMPOSITION, COMPRISING, Diagnostics, IMMUNOGENS, Malaria, Matter, Placental, PROTECT, proteins, That, therapeutics, Used
Category(s): Collaboration Sought > Collaboration
Reducing Bloodstream Neutrophils as a Treatment for Lung Infection and Inflammation
During lung infection, bloodstream neutrophils (PMNs) responding to infection travel to the airspace lumen. Although successful arrival of microbicidal PMNs to the airspace is essential for host defense against inhaled pathogens, excessive accumulation of PMNs in the lung contributes to the pathogenesis of several prevalent lung disorders, including...
Published: 10/28/2024   |   Inventor(s): Carmen Williams, Wan-Chi Lin, Michael Fessler
Keywords(s): 2, BARRIER, DA1XXX, DA3XXX, DA4XXX, DAXXXX, DBXXXX, During, DXXXXX, Epithelial, Infection, Inflammation, INTEGRITY, LUNG, MEMBRANE, PROTECT, Protein, respiratory, Targeting, VJXXXX, VKXXXX, VLXXXX, VPXXXX, WBXXXX, WJXXXX, WKXXXX, XAXXXX, YAXXXX, YBXXXX, YCXXXX
Category(s): Collaboration Sought > Collaboration, ResearchProducts > Antibodies, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Dental, TherapeuticArea > Immunology, TherapeuticArea > Oncology
Device and Method for Protecting Against Coronary Artery Compression During Transcatheter Mitral Valve Annuloplasty
Catheter-based mitral valve regurgitation treatments that use a coronary sinus trajectory or coronary sinus implant can have unwanted effects because the coronary sinus and its branches have been found to cross the outer diameter of major coronary arteries in a majority of humans. As a result, pressure applied by any prosthetic device in the coronary...
Published: 10/28/2024   |   Inventor(s): Ozgur Kocaturk, Robert Lederman, June-Hong Kim
Keywords(s): AA2XXX, AA4CXX, AA4XXX, AAXXXX, AB3FXX, AB3XXX, ABXXXX, Against, Annuloplasty, ARTERIAL, ARTERIES, AXXXXX, Compression, CORONARY, DEVICE, During, Mitral, PMVA, PROTECT, Transcatheter, Vale, Valve
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing