Search Results - mingxuan+zhang

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Chemical Modifications of Substrates Using Zwitterionic-Functionalized Dendrimers
Novel platform for biomaterials development with advanced physiological properties BACKGROUND: The need for improved biomaterials is a continuous challenge in the clinical field. Extended physiological circulation times, reduced immune responses, and lowered cytotoxicity are a few parameters crucial for therapeutic and diagnostic biomaterials. ...
Published: 3/24/2026   |   Updated: 3/23/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents
Functionalized Dendrimers with Regioselective Reactivity
Novel compositions of zwitterionic dendrimers and derived polymers BACKGROUND: There is a strong need for new classes of reactive reagents for the generation of novel materials with pre-defined characteristics. Here, new compounds can be generated employing properties associated with zwitterions, dendrimers, or combination materials. TECHNOLOGY...
Published: 3/24/2026   |   Updated: 3/23/2026   |   Inventor(s): Chong Cheng, Mingxuan Zhang, Yun Wu, Ziwen Zhang
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Biological Materials, Technology Classifications > Diagnostics
Phenotyping Single Ventricle Physiology Using Electronic Health Records (Case Nos. 2025-322 and 2025-323)
Summary: UCLA researchers have created a cutting-edge, automated phenotyping tool that harnesses electronic health records to enable rapid and precise identification of single ventricle physiology (SVP), especially in neonatal and pediatric populations. Background: Single ventricle physiology (SVP) is a rare heart condition that develops before birth...
Published: 1/6/2026   |   Updated: 12/18/2025   |   Inventor(s): Kim-Lien Nguyen, William Hsu, Hang Xu
Keywords(s): Algorithm, cardiac cycle, Cardiovascular, Cardiovascular Disease, cardiovascular diseases, cardiovascular monitoring, cardiovascular prediction, Computer-Aided Diagnosis, heart disease mitigation, heart support, medical automation technology, Medical Device, medical device cardiac monitoring, Medical diagnostics, Medical Guideline, non-invasive cardiac monitoring, Smart medical device, Software, Software & Algorithms, Software Development Tools
Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Cardiac, Medical Devices > Monitoring And Recording Systems
Non-contact railway inspection
VALUE PROPOSITION Rail transportation is periodically marred by accidents, highlighting ongoing safety challenges. There is a need for effective rail inspection methods. Current techniques are hindered by limitations such as low detection accuracy and sensitivity, particularly at high speeds. This technology introduces a novel method for high-speed,...
Published: 9/27/2024   |   Updated: 9/27/2024   |   Inventor(s): Yiming Deng, Sunil Chakrapani, Ming Han, Zebadiah Miles
Keywords(s):  
Category(s): Analytical Instruments, Test and Measurement, Transportation
Whole Tissue Protein Mapping
A tool and method for precise, high-throughput spatial mapping of proteins across whole tissue samples. Background: Spatial proteomics enables delineation of spatial localization of proteins within cells and tissues. This ability to identify and study the relative location and quantification of one or more proteins, whether ones that are endogenously...
Published: 2/19/2026   |   Updated: 7/24/2023   |   Inventor(s): Jun Qu, Ming Zhang, Min Ma
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Bioinformatics
Methods for Modeling Water Quality
­ The Problem: Monitoring and mapping inland water quality is critical for sustainability of water supplies for human consumption, agriculture, industry, and other economic activities. In previous studies, empirical models have been widely used to map water quality parameters for inland waters using remotely sensed imagery. Due to the complex...
Published: 6/2/2023   |   Updated: 8/10/2022   |   Inventor(s): Hongxing Liu, Min Xu, Richard Beck
Keywords(s):  
Category(s): Technology Classifications > Communication, Technology Classifications > Systems & Services
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Updated: 7/14/2022   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Helical Sulfono-γ-AApeptide Antagonize β-Catenin Signaling
Advantages Disrupts protein-protein interactions Mimics the α-helical domain More potent cellular activity Potential anti-cancer therapeutics Exhibits excellent folding stability with defined helices Demonstrates remarkable enzymatic stability for 24 hours Summary Researchers have developed sulfono-γ-AApeptides that are able...
Published: 11/19/2025   |   Updated: 5/16/2022   |   Inventor(s): Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang
Keywords(s): Cancer, Cancer Treatment Leukemias, Cancer Treatment Lymphomas, Peptides, Therapeutics
Category(s): Technology Classifications > Cancer
Anticancer Compounds That Selectively Target and Destroy Cancer-Related Proteins
Demonstrates In Vivo Safety and Efficacy in Breast Cancer Models This set of anticancer compounds selectively degrades or inhibits cancer-related histone deacetylase proteins. These proteins are commonly overexpressed in various cancer types, and class I histone deacetylase proteins activate oncogenes that cause tumor formation, cancer progression,...
Published: 1/20/2026   |   Updated: 11/18/2021   |   Inventor(s): Daiqing Liao, Xuan Zhang, Yufeng Xiao, William Roush, Ryan Stowe, Guangrong Zheng
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
RigNet: Neural Rigging for Articulated Characters
TECHNOLOGY DESCRIPTION Character rigging is the process where animators fit a skeleton to a 3D model, which then allows the animators to manipulate the movement of, or animate, the model. Currently, animators must manually define the skeleton’s joints, how they’re connected, and how the model’s body parts move. This is a very time...
Published: 2/17/2023   |   Updated: 8/20/2021   |   Inventor(s): Evangelos Kalogerakis, Zhan Xu, Yang Zhou
Keywords(s):  
Category(s): Software & information technology, Research tools, Computers, Communications & internet
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