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ID
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Method of T
r
eating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)
UCLA
r
esearchers in the School of Engineering have discovered a novel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zhen Gu
Keywords(s):
glucose intole
r
ance
,
live
r
fibrosis
,
Nanopa
r
ticles
,
Notch signaling pathway
,
obesity
Category(s):
The
r
apeutics > Metabolism And Endocrinology
SELECTIVE SENSITIZATION OF CANCE
R
CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
SELECTIVE SENSITIZATION OF CANCE
R
CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
R
eece Akana
Keywords(s):
Cance
r
,
Immuno-Oncology
,
T-Cell Activation
Category(s):
Technology Classifications > Biology
COMPOSITIONS AND METHODS FO
R
RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
COMPOSITIONS AND METHODS FO
R
RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Cha
r
les Chan
,
Thomas Amb
r
osi
,
I
r
ving Weissman
,
Michael Longake
r
,
R
ahul Sinha
,
Debashis Sahoo
Keywords(s):
Hyd
r
ogel
,
Stem Cell
Category(s):
Technology Classifications > Biology
DESIGN OF UNIVE
R
SAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVE
R
SAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
Pete
r
Kim
Keywords(s):
Immunofocusing
,
Vaccine
Category(s):
Technology Classifications > Biology
NOVEL SMALL MOLECULE NEGATIVE ALLOSTE
R
IC MODULATORS OF THE MU-OPIOD RECEPTOR
NOVEL SMALL MOLECULE NEGATIVE ALLOSTE
R
IC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
Evan Ob
r
ien
,
Kaavya Kuma
r
,
B
r
ian Kobilka
,
Sus
r
uta Majumdar
,
Vipin
R
angari
Keywords(s):
Opiod
,
Pain
Category(s):
Technology Classifications > Chemist
r
y
C41 Analogs
This invention
r
elates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
R
ui Chang
,
Vijayan
R
amachandran
,
Pat
r
ick Ronaldson
Keywords(s):
Category(s):
Technology Classifications > Healthca
r
e Portfolios > Neurology
,
Technology Classifications > Life Sciences > Nut
r
aceuticals
,
Technology Classifications > Life Sciences > Small Molecules
,
Technology Classifications > Life Sciences > The
r
apeutics
,
Technology Classifications > Life Sciences > Biologics
Stimulation Device to t
r
eat Hand Weakness from Stroke or Spinal Injury
A g
r
owing number of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atha
r
va Wani
,
Niteesh Nigam
,
Onka
r
Chavan
,
Yash Bellap
,
Joelly Lobato
,
Ishan Swanand Vyas
,
Suh
r
ud Parag Joglekar
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Medical Devices
,
Manufactu
r
ing/Construction/Mechanical
Vital Signs Monito
r
ing using Depth Cameras
Ca
r
diovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu
R
ong
,
Daniel Bliss
Keywords(s):
Category(s):
Computing & Info
r
mation Technology
,
Medical Devices
,
Life Science (All LS Techs)
,
Medical Diagnostics/Senso
r
s
,
Medical Imaging
Head Motion Co
r
rection with Soft Pressure Pad for MRI Scans
Add
r
essed Need Head motion remains a major challenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diagnostic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
Medical Devices
,
Medical Imaging
Inhibito
r
s of the N-terminal Domain of the Androgen Receptor (UCLA Case No. 2023-075)
R
esearchers at UCLA under the guidance of Drs. Matthew Rettig and Michael Jung have developed novel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
Matthew
R
ettig
,
Michael Jung
Keywords(s):
and
r
ogen receptor therapy
,
cast
r
ation resistant prostate cancer
,
Oncology
,
Oncology (Small Molecules, Peptides and Antibodies)
,
p
r
ostate cancer
,
small molecules
Category(s):
The
r
apeutics > Oncology
,
The
r
apeutics > Oncology > Oncology (Small Molecules)
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