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Title
ID
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A Potent HIV T
r
eatment with Low Toxicity
A small-molecule class that binds to HIV pa
r
ticles to improve immune response and block viral entry into cells. Problem: 37 million people worldwide currently live with HIV and an estimated 2-3 million new infections occur annually. While antiretroviral therapies do exist for those with the disease, therapy interruption leads to the re-emergence of...
Published: 10/30/2025
|
Inventor(s):
Amos Smith
,
Xuchen Zhao
,
Tyle
r
Higgins
,
And
r
es Finzi
,
Shilei Ding
,
Daniel Lee
,
Ma
r
zena Pazgier
,
Dung Nguyen
,
William Tolbe
r
t
Keywords(s):
D
r
ug Target
,
HIV/AIDS
,
Small Molecule
,
Soft Mate
r
ials
Category(s):
Technology Classifications > Chemical P
r
ocesses and Synthesis
,
Technology Classifications > The
r
apeutics
Novel AK
R
1C3 Inhibitors in Cancer
Inhibito
r
s and tools to block the local formation of steroid hormones in hormone-dependent malignancies of the prostate, breast and endometrium Value Proposition: Standard treatment of care for hormone-dependent tumors utilizes hormone ablative therapies. These agents non-discriminately block the action of estrogens and androgens and have untoward side...
Published: 10/30/2025
|
Inventor(s):
T
r
evor Penning
,
Adegoke Adeniji
,
Michael By
r
ns
,
Jeff
r
ey Winkler
,
Ba
r
ry Twenter
,
Law
r
ence Marnett
,
Andy Liedtke
Keywords(s):
Men's Health
,
Oncology
,
Small Molecule
,
Women's Health
Category(s):
Technology Classifications > The
r
apeutics
T Cells Ta
r
geting Misformed Proteins to Treat Neurodegenerative and Muscular Diseases
Antigen-specific immunothe
r
apy with engineered cytotoxic T cells targeting misformed proteins to treat neurodegenerative and muscular diseases. Problem: Neurodegenerative and muscular diseases, such as amyotrophic lateral sclerosis (ALS), inclusion body myositis (IBM), and Alzheimer’s disease (AD), collectively affect over 5 million adults...
Published: 10/30/2025
|
Inventor(s):
Ning Jenny Jiang
,
Shahab Chiza
r
i
Keywords(s):
Bioenginee
r
ing
,
Cell The
r
apy
,
Immunology
,
Immunothe
r
apy
,
Inflammation
,
Neu
r
odegenerative Diseases
Category(s):
Technology Classifications > Diagnostics
,
Technology Classifications >
R
esearch Tools & Reagents
,
Technology Classifications > The
r
apeutics
Seasonally-Adaptive Batte
r
y Thermal Management System for Electric Vehicles
Invention Desc
r
iption Electric vehicles are becoming more common, especially with the push for greater utilization of renewable energy. However, it is widely known that electric vehicles suffer from safety issues associated with mistreatment, collisions, and charging issues. Further, batteries in electric vehicles often have performance degradation...
Published: 10/30/2025
|
Inventor(s):
Moustafa Ame
r
,
Mahmoud Shouman
,
A
r
unachala Kannan
,
Ahmed Hamed
,
Mohamed Salem
Keywords(s):
Category(s):
Physical Science
,
Advanced Mate
r
ials/Nanotechnology
,
Ene
r
gy & Power
The
r
mal Performance Assessment and Management System for Lithium-Ion Batteries
Invention Desc
r
iption Technological breakthroughs in electric batteries have resulted in higher energy density batteries which have risks of overheating during high-rate charging and discharging. This leads to performance degradation, limiting battery lifespan and capacity and hindering widespread battery adoption. Battery management systems (BMSs)...
Published: 10/30/2025
|
Inventor(s):
Moustafa Ame
r
,
Mohamed Salem
,
A
r
unachala Kannan
,
Ahmed Hamed
,
Mahmoud Shouman
Keywords(s):
Category(s):
Advanced Mate
r
ials/Nanotechnology
,
Ene
r
gy & Power
,
Physical Science
T
r
eatment for Dengue Virus (DENV) Infection
Application Antivi
r
al therapeutic for multiple Dengue virus serotypes. Key Benefits Targets conserved regions of DENV genomes, enabling efficacy across serotypes. Mitigates lethal infections with a single lipid nanoparticle (LNP) based dose in mice. Minimal off-target effects. Market Summary Despite 390+ million annual DENV infections, there...
Published: 10/30/2025
|
Inventor(s):
Philip Santangelo
,
Da
r
yll Vanover
,
Chia
r
a Zurla
,
Lo
r
ena Carvalho de Souza Chaves
Keywords(s):
DNA and
R
NA Vaccines
,
D
r
ug Discovery
,
D
r
ug Target Identification
,
Mic
r
obiology and Infectious Disease Treatments
Category(s):
TechPub Algolia > The
r
apeutics
Sphe
r
ical Nucleic Acids with Sheddable PEG Layers
Sphe
r
ical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting NU 2017-169 INVENTORS Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN)) Brian Meckes Wuliang Zhang SHORT DESCRIPTION For oncology applications,...
Published: 10/30/2025
|
Inventor(s):
Keywords(s):
Biologic
,
Bioma
r
ker
,
Biomedical
,
Cance
r
/Oncology
,
Chemicals
,
Diagnostics
,
D
r
ug delivery
,
Nanopa
r
ticle
,
Nanotechnology
,
Pe
r
sonalized medicine
,
The
r
apeutics
Category(s):
Life Sciences > The
r
apeutics
,
Life Sciences > Healthca
r
e Devices, Tools & IT
,
Life Sciences > Bioma
r
kers & Biomedical Research Tools
A lightweight wea
r
able electrode array for electrooculography
T
r
acking eye movement is integral for constructing virtual reality headsets, and in the healthcare sector, eye movement tracking is useful for diagnosing sleep disorders. Current iterations of commercial eye trackers mainly rely on visually tracking the wearer’s retina using head-mounted cameras. This approach suffers from many analytical limitations,...
Published: 10/30/2025
|
Inventor(s):
Deepak Ganesan
,
T
r
isha Andrew
,
Ali Kiaghadi
,
Seyedeh Zoh
r
eh Homayounfar
,
Soha
R
ostaminia
Keywords(s):
Category(s):
Devices & senso
r
s
,
Healthca
r
e
,
Mate
r
ial science
Co
r
d Blood Protein Biomarkers to Identify Early-Onset Neonatal Sepsis
LNU 2024-090 INVENTO
R
S Leena Mithal* SHORT DESCRIPTION A diagnostic assay developed using proteomic biomarkers from umbilical cord blood to rapidly risk stratify newborns for early-onset neonatal sepsis, enabling targeted antibiotic therapy and improved outcomes. BACKGROUND Current approaches to diagnose early-onset sepsis rely on postnatal...
Published: 10/30/2025
|
Inventor(s):
Keywords(s):
Category(s):
Life Sciences > The
r
apeutics
TauSeeK: Disease Specific Tau P
r
otein Fibrils & Seeding Proteins
NU 2024-154 INVENTO
R
S Songi Han* Austin Dubose Michael Vigers Andrew Longhini Vishnu Vijayan Kenneth Kosik Samuel Lobo Peter C. Ryffel Lokeswara Rao Potnuru Karen Tsay Chung-Ta Han SHORT DESCRIPTION Compositions, kits, and methods for generating synthetic miniature tau peptides and fibrils, and synthetic full-length pathogenic tau...
Published: 10/30/2025
|
Inventor(s):
Keywords(s):
Category(s):
Life Sciences > The
r
apeutics
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