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Clonal Spodoptera Frugiperda Cell lines for Enhanced Expression

This technology includes Spodoptera frugiperda (Sf9) cells which were developed to produce recombinant adeno-associated virus. The cells maintain a copy of the vector genome and for production, require infection with a single baculovirus that expresses either structural and nonstructural proteins to produce rAAV, or the non-structural (Rep) proteins...

Published: 8/12/2024 | Inventor(s): Lina Li, Robert Kotin

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Licensing, ResearchProducts > Plasmids/Vectors

Near Real-time, Low-cost, Hand-held Sensors for Measuring Elemental Concentration of Airborne Particles for Indoor or Outdoor Air Quality Monitoring

Airborne particles can have great impact on air quality, weather, and human health. In particular, long-term inhalation of toxic particulate matter in workplaces could pose a significant health risk. NIOSH scientists have developed a new, low-cost approach based on application of atmospheric radio frequency glow discharge (rf-GD) optical emission spectroscopy...

Published: 10/28/2024 | Inventor(s): Lina Zheng, Pramod Kulkarni

Keywords(s): AEROSOLS, analysis, Atmospheric, DART, Discharge, Elemental, Emission, Glow, NIOSH-DART, SPECTROSCOPY, VBXXXX, VPXXXX, WAXXXX, WCXXXX, WEXXXX, WFXXXX, WGXXXX, XGXXXX, XIXXXX, YAXXXX, YFXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Cardiology, Application > Occupational Safety and Health, Application > Vaccines, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Dental, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Consumer Products

Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy

The invention concerns novel capsid-free AAV vectors that can be used for gene delivery and gene therapy applications. The invention provides for a linear nucleic acid molecule comprising in this order: a first adeno-associated virus (AAV) inverted terminal repeat (ITR), a nucleotide sequence of interest, and a second AAV ITR, wherein said nucleic acid...

Published: 10/28/2024 | Inventor(s): Lina Li, Luis Garcia, Cyriaque Beley, Thomas Voit, Robert Kotin

Keywords(s): AAV, Cell, Clonal, Containing, DNA, GB2AXX, Lines, Listed LPM Reichman as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Rescueable, Sf9, STABLE, Vector, VPXXXX, WJXXXX, XEXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease

Self-neutralizing air-breathing thruster and method of neutralization

An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Anmol Taploo, Li Lin

Keywords(s):

Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

Twistron Mechanical Energy Harvesters

Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, automotive technologies, and the extraction of energy from ocean waves. Until now, few harvesters have been flexible enough to be used as yarns in textiles, and the performance of such yarns has been...

Published: 6/26/2024 | Inventor(s): Shi Hyeong Kim, Carter Haines, Na Li, Keon Jung Kim, Tae Jin Mun, Changsoon Choi, Jiangtao Di, Shaoli Fang, Seon Jeong Kim, Ray Baughman

Keywords(s): Automotive, Carbon Nanomaterials, Carbon Nanotubes, Electronics, Energy, Cleantech & Environmental, Engineering & Physical Sciences, Renewable Energy, Sensors & Controls, Textiles, Wireless

Category(s): Nanotechnology

Intelligent Textiles Prepared from Nanofiber Yarns and Polymer Fiber Actuators

While there has always been a desire for smart textiles, including fabrics which adapt depending on environmental stimuli, it has yet to be effectively accomplished due to the lack of suitable materials. These polymer fiber actuators have enabled the creation of fabrics that can reversibly change properties such as porosity, shape, color and texture....

Published: 4/22/2021 | Inventor(s): Ray Baughman, Ozer Goktepe, Fatma Goktepe, Na Li, Marcio Lima, Carter Haines, Shaoli Fang

Keywords(s): Engineering & Physical Sciences, Industrial & Manufacturing, Nanotechnology, Polymers, Textiles

Category(s): Materials

Wireless Steerable Endoscope

Published: 3/26/2020 | Inventor(s): Zheng Li, Sze Hang Calvin Ng, Wai Yan Philip Chiu, Jao Yiu Joseph Sung

Keywords(s):

Category(s): Medical Devices

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