Search Results - john+frelinger

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Protease Activated Cytokines as Anti-Cancer Therapy
A novel therapy method for delivering localized anti-cancer responses without adverse body-wide side effects. Problem Solved by the Technology Despite remarkable success at identifying tumor-associated antigens (TAA), generating effective anti-tumor immune response has not been successful at eliminating tumors. Systemically administered active drugs...
Published: 10/28/2024   |   Inventor(s): John Frelinger, John Puskas, Baek Kim, Mark Sullivan
Keywords(s): Cancer, Immunotherapy, Oncology, Therapy
Category(s): Therapeutic
Coherent Generation Of High-Dimensional Structured Light Using A Hyperdimensional Spin-Orbit Microlaser
The current invention describes next-generation high-capacity noise-resilient communication and computing technology. The invention describes a method to coherently generate high-dimensional structured light, including spin-orbit states, in an integrated and scalable way. Problem: On-chip information technologies are mostly limited to two-level systems...
Published: 10/16/2023   |   Inventor(s): Liang Feng, Zhifeng Zhang, Haoqi Zhao, Li Ge
Keywords(s): Augmented Reality (AR) & Virtual Reality (VR), Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Materials, Technology Classifications > Imaging
Self-neutralizing air-breathing thruster and method of neutralization
An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...
Published: 7/30/2024   |   Inventor(s): Michael Keidar, Anmol Taploo, Li Lin
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 7/30/2024   |   Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Cold atmospheric plasma-stimulated media for treating cancers
For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...
Published: 7/30/2024   |   Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics
Diagnosis of lung cancer subtypes using rapid molecular test
New cancer subtyping system can improve treatment options without disrupting clinical workflow.Problem Lung cancer is the leading cause of cancer death, with over 100,000 people dying per year.1 As most tumors are inoperable by the time the cancer is detected, patients are increasingly being placed on tailored treatment regimens. Prescribing targeted...
Published: 11/1/2023   |   Inventor(s): Livia Eberlin, Erik Cressman, Alena Bensussan, John Lin, Chunxiao Guo, Savitri Krishnamurthy
Keywords(s): Cancer, Diagnostics, Machine learning, Mass spectrometry, Medical devices, Medical imaging, Minimally invasive
Category(s): Life sciences > Diagnostic
Multilayer Batch Microfabricated Magnetic Shielding
UCLA Case No. 2018-014 SUMMARYUCLA researchers in the Department of Electrical Engineering have developed a novel batch microfabrication technique for microscale shielding layers, simultaneously pushing the limits of minimum size, maximum shielding factor, flexibility, and cost.BACKGROUNDCompact electromagnetic shielding paves the way for a new generation...
Published: 7/19/2023   |   Inventor(s): Robert Candler, Jimmy Chen-Yen Wu, Ling Li, Jere Harrison
Keywords(s): Electronics & Semiconductors
Category(s): Electrical > Electronics & Semiconductors, Materials > Fabrication Technologies
Human Glandular Kallikrein (hK2)-Specific Monoclonal Antibodies that Enhance or Inhibit the Enzymatic Activity of hK2
Applications:hK2 is expressed primarily in the prostate, making it an attractive bio-marker for prostate cancer development. A panel of HK2-specific monoclonal antibodies was produced using a tumor-immunization strategy. Compositions, which may be monoclonal antibodies, are specific for hK2 relative to PSA. Compositions either enhance or inhibit...
Published: 10/28/2024   |   Inventor(s): John Frelinger, Terrence Fisher, Mary Ann Nocera-March, Edith Lord
Keywords(s):  
Category(s): Research Tools
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023   |   Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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