Search Results - john+cijiang+he

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Deterministic Fabrication of Site-Controlled Semiconductor Quantum Dots
This technology is a novel technique for the manufacturing of site-controlled GaAs (gallium arsenide) quantum dots (QDs) used in quantum communication and quantum computing. This technique uses an improved local droplet etching (LDE) method. This method allows for control over the location of quantum dot formation. A key innovation of this method is...
Published: 2/5/2026   |   Inventor(s): John Schaibley, Sadhvikas Addamane
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking > Optical, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > MEMS & Nanotechnology, Technology Classifications > Engineering & Physical Sciences > Quantum, Technology Classifications > Engineering & Physical Sciences > Semiconductors, Technology Classifications > Materials > Nanomaterials
Bifunctional fusion protein for biofilm degradation and quorum sensing disruption
Background Bacterial biofilms pose a major challenge in clinical and industrial environments due to their dense extracellular matrix and heightened tolerance to antibiotics and immune responses. Infections involving biofilms, particularly those caused by Pseudomonas aeruginosa, are difficult to eradicate and contribute to chronic wounds, persistent...
Published: 1/30/2026   |   Inventor(s): Hugh Smyth, Tom Smisek, Rex Moore, Nila Murali, John Schroeder, Walter Fast
Keywords(s):  
Category(s): Life sciences > Therapeutics > Biologic
Process for Transforming Waste Polyethylene to Dicarboxylic acids
Executive Summary Polyethylene is a leading plastic used in a myriad of applications. One consequence of the abundant use of the plastic is the problem of waste which accumulates in landfills. Mechanical recycling waste polyethylene is possible for certain grades and limited applications, and pyrolysis to produce fuels possible but often uneconomical....
Published: 2/2/2026   |   Inventor(s): Scott Calabrese Barton, Brandon Howard, John Dorgan
Keywords(s):  
Category(s): Environmental, Recycling
Decreasing enteric methane emission from cattle by inhibition of RNase P, a tRNA biogenesis enzyme
THE CHALLENGE The challenge in reducing enteric methane emissions from ruminant livestock lies not only in the biological complexity of the rumen ecosystem but also in the practical and economic barriers to deploying mitigation strategies at scale. While technologies such as 3-nitrooxypropanol additives, nitrate supplements, and selective breeding...
Published: 1/15/2026   |   Inventor(s): Biswarup Mukhopadhyay, Vaishnavi Sidharthan, John Schneekloth, Venkat Gopalan
Keywords(s):  
Category(s): Technology Classifications > Biotechnology, Technology Classifications > Veterinary Technologies
Novel Channelrhodopsins for Optogenetics Gene Therapy
When expressed in targeted neurons, light-sensitive channelrhodopsin proteins (ChRs) have the ability to selectively manipulate neuronal activity in a light-dependent manner. Gene therapy using anion ChRs (ACRs) has the potential for treating excessive neuron firing in conditions such as Parkinson’s disease, neuropathic pain and epilepsy, while...
Published: 1/15/2026   |   Inventor(s): John Spudich, Elena G Govorunova, Oleg A Sineshchekov
Keywords(s):  
Category(s): Therapeutics, Research Materials
Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects. Background: The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 1/30/2026   |   Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
An Attenuated Vaccine for Lyme Disease
Project ID: TECH2026-05 Background Lyme disease is caused by the gram-negative spirochete Borrelia burgdorferi, as well as other Borrelia species within the Borrelia burgdorferi sensu lato group. B. burgdorferi is known to alter its virulence protein expression profiles depending on its environment. Numerous studies have shown environmental differences...
Published: 2/2/2026   |   Inventor(s): Ronald Wooten, John Presloid
Keywords(s):  
Category(s): Rare Disease
SAGE: A Low-Cost, High-Throughput Disease Agnostic Microfluidic Discovery Engine
This technology relates to a low-cost, high throughput microfluidic platform device which can help identify therapeutic compounds from a known agent, such as tuberculosis. Through a three-chip process, the invention can encapsulate, cultivate, screen and sort bacteria from a host of environmental microbes for bioactive natural products. The platform...
Published: 12/8/2025   |   Inventor(s): Christopher Cartmell, John Streicher
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Research Tools
In Vivo Delivery and Removal of Metals
Current State of the Art: Gold-based drugs are currently used in the treatment of rheumatoid arthritis, have demonstrated efficacy in clinical trials in malaria treatment, and most recently have significantly reduced the reservoir of viral DNA and the population of long-lived HIV-infected memory CD4+ cells in pre-clinical studies. In...
Published: 11/18/2025   |   Inventor(s): John Wataha, Regina Messer, Jill Lewis, David Hobbs
Keywords(s): Biofilter, Heavy metals, Titanates
Category(s): Therapeutics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 1/20/2026   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
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