Search Results - john+cijiang+he

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Organ-on-Chip Apparatus for Quantitative Study of Cellular Interaction with Ultrasound
This is an organ-to-chip device that is constructed by using thin membranes. The device allows quantitative in vitro modeling of cellular interactions by using ultrasound. The technology also has a large potential for therapeutic applications for treating different diseases. The flexibility of organ-on-chip technologies is a great tool to help speed...
Published: 11/6/2024   |   Inventor(s): Jian Gu, Adam Akkad, Frederic Zenhausern
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Life Sciences
Modified kynureninase enzymes for cancer therapy
This invention describes modified kynureninase enzymes, particularly human enzymes, for degrading kynurenine. These enzymes can be used in compositions and methods for treating cancer by depleting kynurenine levels. Background Cancer immunotherapy has emerged as a promising approach to treating a wide range of malignancies. The goal of immunotherapy...
Published: 11/5/2024   |   Inventor(s): George Georgiou, Everett Stone, John Blazeck, Nicholas Marshall, Wei-Cheng Lu
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Gene therapy
Novel cermet composite for nuclear waste immobilization
​ 1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...
Published: 10/9/2024   |   Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso
Keywords(s):  
Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
Novel cermet composite for nuclear waste immobilization
​ 1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...
Published: 10/9/2024   |   Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso
Keywords(s):  
Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
Food Demonstration Guide
The Food Demonstration Guide is a comprehensive resource developed to enhance the quality and safety of food demonstrations conducted under the Arizona Department of Health Services' Supplemental Nutrition Assistance Program Education (SNAP-Ed) and Women, Infants, and Children (WIC) programs. This guide aims to train SNAP-Ed and WIC staff on best...
Published: 10/9/2024   |   Inventor(s): Jennifer Parlin, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Creative Works, Technology Classifications > Agriculture & Horticulture > Food Science & Nutrition
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 10/3/2024   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Innovative vibrational system for the trunk proprioceptive impairment study
Reference #: 1664 The University of South Carolina is offering licensing opportunities for Innovative vibrational system for the trunk proprioceptive impairment study. Background: One of the key human feedback systems is somatosensory system. The somatosensory system transmits proprioceptive, or body segment position sense, information from sensors...
Published: 9/26/2024   |   Inventor(s): Debdyuti Mandal, Sourav Banerjee, John Gilliam, Sheri Silfies
Keywords(s):  
Category(s): Advanced Materials, Engineering and Physical Sciences, Environmental and Sustainability
Cu-Ni fuel cell catalysts for dehydrogenation of methylcyclohexane
Reference #: 1670 The University of South Carolina is offering licensing opportunities for Cu-Ni fuel cell catalysts for dehydrogenation of methylcyclohexane. Background: On-board storage of H2 in a safe format has limited the use of fuel cells in mobile transportation applications. Cylinders of compressed H2 will be difficult to implement due to...
Published: 9/26/2024   |   Inventor(s): John Monnier, John Meynard Tengco, Haiying Zhou, Yanjiao Yi
Keywords(s):  
Category(s): Engineering and Physical Sciences, Environmental and Sustainability, Advanced Materials
Engineered enzymes for enhanced kynurenine degradation in cancer therapy​​
The technology describes a modified human kynureninase enzyme with enhanced catalytic efficiency for degrading kynurenine, achieved through specific amino acid substitutions. This enzyme, used in therapeutic applications, reduces kynurenine levels to mitigate tumor-mediated immune suppression and promote anti-tumor immune responses. Background Cancer...
Published: 11/5/2024   |   Inventor(s): George Georgiou, Everett Stone, John Blazeck
Keywords(s):  
Category(s): Life sciences > Therapeutics > Gene therapy, Life sciences > Research tools > Tool/assay/screening platform
Pharmacologically optimized human kynureninase variants for cancer treatment
­The invention describes a modified kynureninase enzyme with enhanced catalytic efficiency and stability for therapeutic applications, particularly in cancer treatment. It depletes kynurenine, aiding cancer therapy alone or with other treatments, and can be PEGylated for increased in vivo half-life. Background Cancer cells often manipulate metabolic...
Published: 11/5/2024   |   Inventor(s): George Georgiou, Everett Stone, John Blazeck, Christos Karamitros
Keywords(s):  
Category(s): Life sciences > Therapeutics > Gene therapy, Life sciences > Research tools > Tool/assay/screening platform
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