Search Results - mehdi+mollapour

2 Results Sort By:
Small Peptides Targeting Lactate Dehydrogenase-A
This technology presents engineered peptide inhibitors designed to selectively block lactate dehydrogenase A (LDHA) activity, offering a novel therapeutic approach for diseases characterized by elevated LDHA, such as cancer and metabolic disorders. Background: Lactate dehydrogenase A (LDHA) is an enzyme that plays a key role in cellular metabolism...
Published: 6/12/2026   |   Updated: 6/12/2026   |   Inventor(s): Mehdi Mollapour, Gennady Bratslavsky, Mark Woodford
Keywords(s): FLCN, lactate dehydrogenase, metabolic switch, tumor suppressor, Warburg effect
Category(s): Campus > Upstate Medical University
Targeting the Folding of Hsp90 Clients by Predicting Their Local Unfolding Status
Computationally predicts potential ideal interaction points for the molecular chaperone heat shock protein-90 (Hsp90). Background: Molecular chaperones assist in the folding of unfolded and misfolded polypeptides by stabilization of folding intermediates and prevention of protein misfolding and aggregation. Molecular chaperones are present in all...
Published: 6/12/2026   |   Updated: 5/13/2025   |   Inventor(s): Mehdi Mollapour, Giorgio Colombo, Mark Woodford, Gennady Bratslavsky, Dimitra Bourboulia
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines