Search Results - jiayun+li

16 Results Sort By:
Inhibition of T Cell Differentiation and Senescence by Overexpression of Transcription Factor c-Myb
Abstract: Adoptive Cell Therapy (ACT) is a promising technique that uses a patient's own T cells to treat cancer. The process requires removing and engineering a patient's T cells to express a chimeric antigen receptor (CAR) or T cell receptor (TCR) that targets a specific cancer antigen. When the modified T cells are reintroduced into the patient,...
Published: 4/8/2024   |   Inventor(s): Sanjivan Gautam, Yun Ji, Luca Gattinoni
Keywords(s): act, Adoptive Cell Transfer, CANCER, CAR, chimeric antigen receptor, Gattinoni, Immunotherapy, Infectious Disease, Stem Cell, T cell, T Cell Receptor, TCR
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Overexpression of Phf19 on T Cells Enhances Therapeutic Effects of T Cell-Based Therapies (such as Chimeric Antigen Receptor [CAR] Therapies)
Abstract: T cell-based immunotherapy (such as CAR therapies) is a promising approach for the treatment of several cancers. However, T cells currently employed for various T cell-based immunotherapies are usually senescent and terminally differentiated leading to poor proliferative and survival capacity, limiting their therapeutic effectiveness once...
Published: 4/8/2024   |   Inventor(s): Yun Ji, Luca Gattinoni
Keywords(s): CAR-T Therapy, CD8, chimeric antigen receptor, Gattinoni, Phf19, T cell
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics
The Growing Role of Digital Pathology and Machine Learning in Cancer Diagnostics (UCLA Case No. 2021-134)
Summary: Researchers at UCLA's Department of Radiological Sciences have developed an active learning methodology for digital pathology image analysis, addressing challenges posed by inconsistent annotations and revolutionizing the training of diagnostic algorithms. Background: The global digital pathology market is anticipated to experience significant...
Published: 8/9/2023   |   Inventor(s): Corey Arnold, Wenyuan Li, Jiayun Li, William Speier
Keywords(s): active learning, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Artificial Neural Network, artificial-intelligent materials, computational imaging task, convolutional networks, curriculum learning, Deep Learning, deep physical neural network, Digital Pathology, dynamic identification, Histopathological image analysis, histopathology images, Image Processing, Magnetic Resonance Imaging Pathology, Medical Devices and Materials, Medical Imaging, noisy annotations, noisy label detection, pathology image analysis
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Electrical > Imaging, Medical Devices > Medical Imaging
Multi-Resolution Model With Attention for Whole Slide Image Analysis Trained Using Weak Labels (UCLA Case No. 2019-943)
Summary: UCLA Researchers in the Department of Radiology have developed a computer-aided diagnostic model that uses histology slides to interpret and detect prostate cancer diagnoses with high levels of accuracy. Background: In the United States, prostate cancer ranks as the most prevalent and second deadliest cancer among men. Diagnosing this...
Published: 7/10/2024   |   Inventor(s): Corey Arnold, Jiayun Li, William Speier
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Artificial Neural Network, Digital Health, Digital Holography, Digital immunohistology, Digital Pathology, Machine Learning, Magnetic Resonance Imaging Pathology, MRI
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Optics & Photonics
Real-Time RT-PCR Assay for the Rapid Detection of Rabies and Other Lyssaviruses
Rabies occurs in more than 150 countries and territories, resulting in at least 55,000 human deaths per year worldwide according to World Health Organization estimates. Rabies is a vaccine-preventable viral disease caused by numerous lyssaviruses that are found in a variety of animal species throughout the world. Rabies virus infects the central nervous...
Published: 10/28/2024   |   Inventor(s): Yu Li
Keywords(s): assay, DA4XXX, DDXXXX, Diagnostics, LYSSAVIRUSES, Modified, NCEZID, NCEZID-DHCPP, Non-rabies, Probe, rabies, REAL-TIME, RT-PCR, VLXXXX, VOXXXX, WBXXXX, WGXXXX, WHXXXX, WIXXXX, XEXXXX, YBXXXX, YGXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Therapeutics, Application > Research Materials, Application > Diagnostics
Universal Diagnostic Assay for Detection and Identification of Poxviruses in Clinical Samples
CDC researchers have developed an assay for detection and diagnosis of poxviruses within clinical samples or from lab culture-systems. The assay specifically targets chordopoxviruses (except avipoxviruses) for PCR-based identification; an improvement upon the current standard of cell culturing methodologies. Individual chordopoxvirus species can cause...
Published: 10/28/2024   |   Inventor(s): Inger Damon, Hui Zhao, Yu Li
Keywords(s): ASSAYS, CDC Docket Import, CDC Docket Import CDC Prosecuting, CHORDOPOXVIRUSES, DA4BXX, DA4XXX, DAXXXX, diagnostic, DXXXXX, OID-NCEZID-DHCPP, VLXXXX, VOXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Diagnostics, Application > Research Materials
Fabrication of metal-insulator-semiconductor photoelectrodes
Background Photoelectrochemical (PEC) water splitting is a promising technology for converting solar energy into clean and storable chemical energy. In PEC cells, semiconductors play a key role in absorbing photons from the light source to create mobile charge carriers. Various semiconductor materials have been studied for the high-performance PEC cells,...
Published: 12/11/2023   |   Inventor(s): Edward Yu, Soonil Lee, Li Ji
Keywords(s):  
Category(s): Physical sciences > Semiconductor, Physical sciences > Green tech
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
2016-409 Fluid Manipulation by Electrodewetting
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel method that allows the manipulation of liquid droplets on a surface. Background: Electrode wetting on dielectric (EWOD) is a well-known effect that involves application of electric field to move or modify a fluid droplet. It is most commonly...
Published: 10/3/2023   |   Inventor(s): Chang-Jin Kim, Jia Li
Keywords(s): Microfluidics And Mem's
Category(s): Life Science Research Tools > Microfluidics And Mems
1 2