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Antimicrobial Antibody Signatures of IBD
The incidence of inflammatory bowel disease (IBD), which includes Chron’s disease (CD) and ulcerative colitis (UC), is increasing globally, as is the healthcare burden, with studies showing it as one of the top 5 most expensive GI conditions. Early and accurate diagnosis is strongly associated with better patient outcomes. However, the common...
Published: 8/27/2025   |   Inventor(s): Mahasish Shome, Lusheng Song, Yunro Chung, Jonathan Leighton, Joshua LaBaer, Ji Qiu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Lignin-Based Separators for Lithium-Ion Batteries
Executive Summary Lithium ion batteries are currently ubiquitous in numerous applications. In these batteries, the separator plays a crucial role by physically separating the anode and cathode to prevent electrical short circuits while allowing the flow of ions through the electrolytes. Common materials used for separators include polyolefins such...
Published: 8/15/2025   |   Inventor(s): Chengcheng Fang, Huanhuan Jia
Keywords(s): Lignin, Lithium Batteries
Category(s): Advanced Materials, Energy
P4Control: Line-Rate Cross-Host Attack Prevention via In-Network Information Flow Control Enabled by Programmable Switches and eBPF
THE CHALLENGE Modern targeted attacks, such as Advanced Persistent Threats (APTs), often use multiple hosts as stepping stones and move laterally across them to gain deeper access to the network to access unauthorized resources or exfiltrate sensitive data. These sophisticated cross-host attacks present significant challenges to existing security...
Published: 8/14/2025   |   Inventor(s): Osama Bajaber, Bo Ji, Peng Gao
Keywords(s):  
Category(s): Technology Classifications > Security, Technology Classifications > Software
Biodegradable Polymers for Gene Delivery
​ Invention Summary: In gene therapy, a key challenge is delivering therapeutic genes to target cells, which requires gene delivery vectors. While viral vectors are effective, they pose risks such as immune responses and toxicity. Non-viral vectors, particularly cationic polymers, are preferred for their safety, cost-effectiveness, and high...
Published: 8/20/2025   |   Inventor(s): Adam Gormley, David Radford, Prajakatta Mulay, Jia Niu, Brayan Rondon
Keywords(s):  
Category(s): Technology Classifications > Agriculture, Technology Classifications, Technology Classifications > Physical Sciences & Engineering
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 5/13/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity. Background: Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 5/13/2025   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
Injectable Nanogel for Immune Modulation Therapy
A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis. Background: Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 5/13/2025   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Drug Discovery Based on Surface-Enhanced Raman Spectroscopy (SERS)
Enables drug discovery without introducing modifications to the molecules, while lowering costs by requiring only small amounts of the tested molecules. Background: Surface-enhanced Raman spectroscopy (SERS) is a novel, label-free, sensitive, specific, fast, and relatively inexpensive tool for drug discovery. It offers the potential to detect and...
Published: 5/13/2025   |   Inventor(s): Igor Lednev, Lamyaa Almehmadi, Jia Sheng
Keywords(s): Raman spectroscopy, RNA, RNA chemistry, TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Bouquet Fiber-based Neural Probe
THE CHALLENGE Neural probes are the key to unlocking the brain’s mysteries, yet current designs remain woefully inadequate. Most cutting-edge probes rely on outdated tip-based interactions, offering only a narrow, fragmented view of neural activity while leaving vast brain regions unexplored. Bulky, rigid structures provoke inflammation and...
Published: 6/30/2025   |   Inventor(s): Xiaoting Jia, Shan Jiang
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Electronics, Technology Classifications > Biotechnology, Technology Classifications > Biomedical
Nanoparticles for Precise & Targeted Treatment of Neurological Conditions
Problem: Acute ischemic stroke (AIS) is the second leading cause of death worldwide, affecting around 600,000 Americans annually. However, pharmacological treatment of AIS is difficult due to ineffective and nonspecific targeting to blood brain barrier epitopes via intravenous administration. Over 100 drugs have been tried and failed in clinical trials...
Published: 8/6/2025   |   Inventor(s): Oscar Marcos Contreras, Jacob Brenner, Vladimir Muzykantov, Jia Nong, Patrick Glassman, Drew Weissman, Sahiley Reyes-Esteves
Keywords(s): Drug Delivery, Inflammation, Nanotechnology, Neurology
Category(s): Technology Classifications > Therapeutics
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