Search Results - jia+jia

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Bouquet Fiber-based Neural Probe
THE PROBLEM Neural probes are the key to unlocking the brain’s mysteries, yet current designs remain woefully inadequate. Most cutting-edge probes rely on outdated tip-based interactions, offering only a narrow, fragmented view of neural activity while leaving vast brain regions unexplored. Bulky, rigid structures provoke inflammation and tissue...
Published: 4/10/2025   |   Inventor(s): Xiaoting Jia, Shan Jiang
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Electronics, Technology Classifications > Biotechnology, Technology Classifications > Biomedical
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 4/1/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity. Background: Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 4/1/2025   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
Injectable Nanogel for Immune Modulation Therapy
A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis. Background: Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 4/1/2025   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Drug Discovery Based on Surface-Enhanced Raman Spectroscopy (SERS)
Enables drug discovery without introducing modifications to the molecules, while lowering costs by requiring only small amounts of the tested molecules. Background: Surface-enhanced Raman spectroscopy (SERS) is a novel, label-free, sensitive, specific, fast, and relatively inexpensive tool for drug discovery. It offers the potential to detect and...
Published: 4/1/2025   |   Inventor(s): Igor Lednev, Lamyaa Almehmadi, Jia Sheng
Keywords(s): Raman spectroscopy, RNA, RNA chemistry, TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Nanoparticles for Precise & Targeted Treatment of Neurological Conditions
Problem: Acute ischemic stroke (AIS) is the second leading cause of death worldwide, affecting around 600,000 Americans annually. However, pharmacological treatment of AIS is difficult due to ineffective and nonspecific targeting to blood brain barrier epitopes via intravenous administration. Over 100 drugs have been tried and failed in clinical trials...
Published: 2/20/2025   |   Inventor(s): Oscar Marcos Contreras, Jacob Brenner, Vladimir Muzykantov, Jia Nong, Patrick Glassman, Drew Weissman, Sahiley Reyes-Esteves
Keywords(s): Drug Delivery, Inflammation, Nanotechnology, Neurology
Category(s): Technology Classifications > Therapeutics
Biocompatible Strain Sensing Polymer Fiber
THE CHALLENGE Strain sensing has large implications in biomedical applications to monitor wearer’s physiological conditions. Current metal or silicon based strain sensors cannot sense small deformations (less than 5%) & are not biocompatible, thus are not suitable for human health monitoring. These strain sensors are usually not very flexible...
Published: 4/9/2025   |   Inventor(s): Yujing Zhang, Xiaoting Jia
Keywords(s):  
Category(s): Technology Classifications > Electronics
Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations
The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Planner – Planning Software for Near-Earth Object Survey Operations
The Planner subsystem in the Catalina Sky Survey (CSS) software suite is designed to help observers efficiently plan nightly asteroid and Near-Earth Object (NEO) observations. By displaying a virtual map of the sky, it helps ensure that areas previously searched, or areas unlikely to be productive, are avoided. The map shows the telescope’s current...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Processing – Software to Process and Analyze Images for NEO Survey
The Processing subsystem in the Catalina Sky Survey (CSS) software suite is a streamlined pipeline designed to handle raw images captured by telescopes during asteroid and Near-Earth Object (NEO) surveys. This pipeline processes the images through multiple stages, such as calibrating for optical distortions, extracting star or asteroid positions, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
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