Search Results - chengzhou+zhu

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YAP-TEAD Core Inhibitors for Developing Cancer Therapeutics

Inhibit YAP-TEAD Interactions for the Treatment of Diseases with Altered Hippo Signaling These small molecule inhibitors target TEA domain (TEAD) proteins, with the potential to treat diseases with altered Hippo signaling, such as Hepatocellular Carcinoma (HCC) and Hepatoblastoma (HB). The Hippo signaling pathway is vital to organ growth control, stem...

Published: 9/3/2024 | Inventor(s): Chenglong Li, Chen Zhou, Liya Pi, Chunbao Sun

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Therapeutics

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...

Published: 8/17/2023 | Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang

Keywords(s): EEG, Neurology, Wearable

Category(s): Technology Classifications > Engineering

A novel method to fabricate nanostructured bulk materials with tailored grain-boundary conditions

Overview Engineering at the grain boundary - the meeting points of where the crystals or grains of varying size and orientation that comprise a material meet—is crucial to fully utilizing a new material. This area of research is pivotal to fully utilizing the mechanical, electrical, and thermal transport properties of a variety of materials....

Published: 5/21/2023 | Inventor(s): Ou Chen, Yasutaka Nagaoka

Keywords(s):

Category(s): Engineering and Sensors

Platform for Quantification of Transmembrane Protein Binding Kinetics

Membrane proteins, notably G-protein-couple receptors (GPCRs), are responsible for many critical cellular functions and are an important family of drug targets. Because of this, it is important to measure their binding activities with molecular ligands and drug candidates. Studying membrane proteins is challenging for two reasons. The first is...

Published: 2/23/2023 | Inventor(s): Shaopeng Wang, Zijian Wan, Heng Zhu

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, Applied Technologies, Cancer, Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

Low Cost and High Performance Transition-Metal-Based Electrocatalysts for Water Splitting

Unmet Need : Accommodating the unpredictable and intermittent nature of renewable energy requires efficient energy storage and conversion devices. One of the most promising solutions is to convert renewably generated electricity into fuels, such as hydrogen, methane, and ethanol. Electrolysis of water is considered an easy and clean method to obtain...

Published: 10/8/2024 | Inventor(s): Yuehe Lin, Chengzhou Zhu, Shaofang Fu, Dan Du

Keywords(s): amorphous catalyst, NiFe alloys, oxygen evolution reaction, porous nanostructures, Water Splitting

Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Next Generation Materials & Technology > Nanotechnology

2015-671 Underground Shafts for Hydrogen Storage

SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...

Published: 7/19/2023 | Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove

Keywords(s): Energy & Water

Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage

Method to actively control the direction of hydraulic fractures using ultrasonic waves

Hydraulic fracking has revolutionized the oil industry since the first successful application in 1950. In hydraulic fracking, high pressure fluids are injected into wells in order to crack and thereby render the oil containing substrate more permeable thus allowing the entrapped oil and gas to flow more freely. Wells may be drilled vertically hundreds...

Published: 11/2/2024 | Inventor(s): Cheng Zhu

Keywords(s): Environmental , Fracking, Oil & Gas, Ultrasonic

Category(s): Environment

Portable, inexpensive shield that inflates to protect against personal injury caused by falling debris and building collapse in earthquakes

TechnologyPopulations continue to increase in areas that have high levels of seismic activity, especially in urban communities along the western United States, Japan, China, South America, and India. By 2030, approximately 60 percent of the global population or approximately 5 billion people are expected to live in urban areas. Building construction...

Published: 3/6/2024 | Inventor(s): Charles McGlynn, Cheng Zhu

Keywords(s): Disaster, Earthquake, Portable, Protection

Category(s): Environment, Engineering > Materials

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