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YAP-TEAD Core Inhibitors for Developing Cancer Therapeutics
Inhibit YAP-TEAD Interactions for the Treatment of Diseases with Altered Hippo Signaling These small molecule inhibitors target TEA domain (TEAD) proteins, with the potential to treat diseases with altered Hippo signaling, such as Hepatocellular Carcinoma (HCC) and Hepatoblastoma (HB). The Hippo signaling pathway is vital to organ growth control, stem...
Published: 9/3/2024   |   Inventor(s): Chenglong Li, Chen Zhou, Liya Pi, Chunbao Sun
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Category(s): Technology Classifications > Human Health Care > Therapeutics