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Search Results - chenglong+li
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YAP-TEAD Core Inhibitors for Developing Cancer Therapeutics
Inhibit YAP-TEAD Interactions for the Treatment of Diseases with Altered Hippo Signaling These small molecule inhibitors target TEA domain (TEAD) proteins, with the potential to treat diseases with altered Hippo signaling, such as Hepatocellular Carcinoma (HCC) and Hepatoblastoma (HB). The Hippo signaling pathway is vital to organ growth control, stem...
Published: 9/3/2024
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Inventor(s):
Chenglong Li
,
Chen Zhou
,
Liya Pi
,
Chunbao Sun
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
Human Monoclonal Antibodies to Generate Chimeric Antigen Receptor (CAR) T-cells to Treat Patients with Advanced Clear Cell Renal Cell Carcinoma (ccRCC).
This technology includes six human monoclonal antibodies (mAbs) that target tumor antigens derived from the CT-RCC HERV-E (human endogenous retrovirus type E) to generate Chimeric Antigen Receptor (CAR) T cells to treat patients with advanced clear cell renal cell carcinoma (ccRCC). These mAbs were identified from Adagene Inc’s human antibody...
Published: 8/12/2024
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Inventor(s):
Richard Childs
,
Long Chen
,
Elena Cherkasova
Keywords(s):
Category(s):
Application > Diagnostics
,
Application > Research Materials
,
Collaboration Sought > Licensing
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Collaboration Sought > Materials Available
,
ResearchProducts > Antibodies
,
TherapeuticArea > Oncology
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...
Published: 8/17/2023
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Inventor(s):
Ada Poon
,
Cheng Chen
,
Joonseok Yang
,
Hui Wang
Keywords(s):
EEG
,
Neurology
,
Wearable
Category(s):
Technology Classifications > Engineering
Thermal Drift Calibration of Whispering Gallery Mode Microcavities using Optical Frequency Domain Reflectometry
This technology utilizes optical frequency domain reflectometry (OFDR) to collect high resolution temperature measurements in biochemical applications. More specifically, accuracy of measurements is increased in the spatial domain via the OFDR technology being studied in conjunction with whispering gallery mode biochemical sensing. While temperature...
Published: 6/6/2024
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Inventor(s):
Tsu-Te Su
,
Cheng Li
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Telecommunications > Electro-Optic Devices
Novel Multi-Omics Aging Clock
A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024
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Inventor(s):
George Sutphin
,
Samuel Freitas
,
Megha Padi
,
Chen Chen
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Research Tools > Animal Models
,
Technology Classifications > Research Tools > Screening assays
,
Technology Classifications > Research Tools > Simulators and Modeling Tools
Autonomous Drone for railroad track inspection
Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...
Published: 3/15/2023
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Inventor(s):
Yu Qian
,
Yi Wang
,
Chen Chen
Keywords(s):
autonomous drone
,
flight control
,
image processing
,
railroad track inspection
,
self-navigation
Category(s):
Engineering and Physical Sciences
Scalable two-phase cooling plates
Reference #: 01575 The University of South Carolina is offering licensing opportunities for Scalable two-phase cooling plates Background: Two-phase cooling usually fails at relatively low heat loads due to the loss of liquid supply. For real applications, two-phase cooling technologies need to match the size of electronic components. However, the...
Published: 11/7/2022
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Inventor(s):
Chen Li
,
Wei Chang
,
Enrico Santi
,
Bo Tian
Keywords(s):
cold plate
,
high power device
,
Thermal management
,
Two-phase cooling
Category(s):
Engineering and Physical Sciences
,
Software and Computing
Small Molecule Inhibitors Against Cancer-Associated Protein
Demonstrate a High Potency In Vivo, Making Them Strong Therapeutic Candidates for Cancer and Autoimmune Disorders These small molecules are inhibitors against protein arginine methyltransferase 5, which plays a role in tumor development and is overexpressed in several cancers, including lymphoma, glioblastoma, colorectal cancer, and prostate cancer....
Published: 7/12/2022
|
Inventor(s):
Chenglong Li
,
Xiaozhi Yang
,
Wei Zhou
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Analog-to-digital converter (ADC) technologies
Background Dr. Nan Sun and his research group have developed a portfolio of analog to digital converter (ADC) technologies that are available for licensing. Overall, Dr. Sun’s lab develops high-performance analog/mixed-signal circuits and architectures, with research efforts focusing primarily on designing low-power, high-speed, and high-resolution...
Published: 11/1/2023
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Inventor(s):
Nan Sun
,
Wenjuan Guo
,
Long Chen
,
Xiyuan Tang
,
Linxiao Shen
,
Chen-Kai Hsu
Keywords(s):
Category(s):
Physical sciences > Computer hardware
,
Physical sciences > Semiconductor
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