Search Results - -microbiology

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A Method for Modulating Hydrogen Sulfide Concentrations in the Human Intestine
Engineered bacteria (smart probiotics) have been developed to sense and modify harmful sulfur species and specifically hydrogen sulfide in the gut for the treatment of intestinal diseases such as IBD. https://nu.testtechnologypublisher.com/files/sites/vaibhav-1280x1600.jpeg https://nu.testtechnologypublisher.com/files/sites/adobestock_586108897.jpeg Source:...
Published: 10/15/2024   |   Inventor(s): Justin Hayes, Benjamin Woolston
Keywords(s): Biotech, Gastrointestinal Disease, Medical/Health, Metabolic Engineering, Microbiology
Category(s): -Health, -Microbiology, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bio-sensors, -Chemistry, -Biology
Method and Device for Cultivation and Analysis of Novel Microbial Species with Unknown Growth Requirements
INV-15097 Background: The annual death rate due to antibiotic resistance was expected to reach 10 million by 2050. However, no new class of antibiotics has been introduced as a successful treatment option since 1987. Lack of new antibiotics is due to the fact that we do not have access to many microbial species in their natural environment, or we...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s):  
Category(s): -Microbiology
Contactless Optothermal Heating of Silicon Nitride for Instant Temperature Control of Individual Particles, Molecules, and Molecular Complexes near Surfaces
INV-17039 Background A nanopore is a nanoscale hole through a solid-state impermeable membrane that separates two electrolyte buffer reservoirs. The nanopore is filled with the same electrolyte buffer, which makes a liquid junction between the two reservoirs. The temperature at the nanopore is measured by tracking the ion current through the pore,...
Published: 10/15/2024   |   Inventor(s): Meni Wanunu, Hirohito Yamazaki
Keywords(s):  
Category(s): -Microbiology
Functional phenotyping of cells in droplet based platforms
INV-16003 Background Recently, the development of microfluidic, technology-enabled analysis of cell phenomena on the single-cell level has been a growing area of research within the academic realm. Current microfluidic platforms based on micro-well technologies do not provide a robust protocol for cell co-encapsulation in a controllable microenvironment,...
Published: 10/15/2024   |   Inventor(s): Tania Konry, Saheli Sarkar
Keywords(s): Diagnostics, Microfluidics, Singe cell
Category(s): -Microbiology, Technology Classifications > 1. Life Science > Therapeutics
METHODS AND COMPOSITIONS FOR HIGH-RESOLUTION SEQUENCE ANALYSIS OF INDIVIDUAL LONG AND ULTRALONG NUCLEIC ACID MOLECULES
INV-20100 Background Accurate analysis of the precise order of nucleotides in deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) molecules is fundamentally important to understanding the biology and function of all living organisms, including viruses. Since the complete sequence of nucleic acid was first reported in 1965, technologies for DNA...
Published: 9/10/2024   |   Inventor(s): Zoe Fleischmann, Konstantin Khrapko, Dori Woods, Jonathan Tilly
Keywords(s):  
Category(s): -Microbiology
Method and Device for Drug Discovery
INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool
Category(s): -Analytical Chemistry, -Health, -Microbiology, Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Drug Discovery