Search Results - -analytical+chemistry

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A probiotic product for detoxification of the recreational drug gamma-hydroxybutyric acid (GHB)
INV-20018 Background GHB is a naturally occurring neurotransmitter and a psychoactive drug. It is a precursor to γ-aminobutyric acid (GABA) and glutamate in certain brain areas. GHB has been used for recreational purposes as a club drug and, in some instances, leads to drug-facilitated sexual assault. When over-dosed, GHB can cause severe...
Published: 9/10/2024   |   Inventor(s): Yunrong Chai, Yuxuan Qin
Keywords(s): Biomolecules, Drugs, Medical/Health
Category(s): -Analytical Chemistry, -Health
Rapid Gas-Phase Isotopic Labeling for Enhanced Detection of Protein Conformations
collapse: collapse; } INV-0940 Background Sensitive analytical tools are needed for the rapid characterization of conformations of both small globular proteins and large macromolecular complexes. Characterization of non-native conformational structures, including misfolded proteins and aggregated proteins is highly important in the detection of...
Published: 9/10/2024   |   Inventor(s): John Engen, Kasper Dryberg Rand
Keywords(s): Chemistry, Detection
Category(s): -Analytical Chemistry, Technology Classifications > 2. Physical Science > Lab tech/equipment
Platinum Alloy Electrocatalysts with Enhanced Resistance to Anion Poisoning for Low and Medium Temperature Fuel Cells
A novel approach that enables the development of platinum based binary and ternary alloy electro-catalysts Institute Reference: INV-0863 Background Proton exchange membrane (PEM) fuel cells are useful due to their high energy density, high efficiency, relatively low operating temperature and low emission of pollutants. However, low performance of...
Published: 9/10/2024   |   Inventor(s): Sanjeev Mukerjee
Keywords(s):  
Category(s): -Analytical Chemistry
Hydrogel with Initiator-Tightened Surface
INV- 1007 Background The absence of highly porous, uniformly nanoporous surfaces places limitations on handling, fractionating, extracting, recovering and concentrating aqueous and nonaqueous samples of chemicals and biological substances, both soluble and insoluble. For example, if the surface is not highly porous, then a process that depends on...
Published: 9/10/2024   |   Inventor(s): Roger Giese, Gang Shao
Keywords(s): Analytical Chemistry, Chemistry, Drug Discovery & Development, Research Tool, Screening Tool
Category(s): -Analytical Chemistry, -Chemistry, -Materials, Technology Classifications > 2. Physical Science > Lab tech/equipment
Method and Device for Drug Discovery
INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool
Category(s): -Analytical Chemistry, -Health, -Microbiology, Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Drug Discovery