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Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...

Published: 8/22/2024 | Inventor(s): Ming Xian, Hua Wang, Yu Zhao

Keywords(s): Chemistry

Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical

DNA Nanocaged Enzymes

Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...

Published: 2/23/2023 | Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao

Keywords(s): Bioanalysis, Catalysis, Enzymes

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors

Biological H2S / COS Donation by Thiocarbamates

University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...

Published: 5/2/2022 | Inventor(s): Michael Pluth, Andrea Steiger, Yu Zhao

Keywords(s):

Category(s): Chemistry, Physical Science, Therapeutics

Compounds for Thiol-Triggered COS and/or H2s Release and Methods of Making and Using the Same

Published: 5/2/2022 | Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda

Keywords(s): Science

Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics

Gamma-ketothiocarbamate molecules that release COS

Published: 5/2/2022 | Inventor(s): Michael Pluth, Yu Zhao

Keywords(s):

Category(s): Chemistry, Diagnostics, Engineering, Medical Devices, Physical Science, Research Tools, Therapeutics

2015-182 FLEXIBLE BALLOON-INFLATABLE ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY TO ASSESS ENDOLUMINAL LIPID-RICH LESIONS

Case No. 2015-182SUMMARYUCLA researchers have developed a novel flexible balloon-inflatable electrochemical impedance spectroscopy to facilitate the diagnosis of metabolically active atherosclerotic lesions.BACKGROUNDIdentifying metabolically active atherosclerotic lesions remains an unmet clinical challenge during coronary intervention. Detection of...

Published: 8/9/2024 | Inventor(s): Fei Yu, Yu-Chong Tai, Yu Zhao, Tzung Hsiai

Keywords(s): Cardiovascular, Medical Devices and Materials, Monitoring And Recording Systems

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular

Enhanced Imaging for Quantification of Complex Discontinuity in Plate-like Structures

Reference #: 01325The University of South Carolina is offering licensing opportunities for Enhanced Imaging for Quantification of Complex Discontinuity in Plate-like StructuresBackground:Structural health monitoring (SHM) and Nondestructive Evaluation (NDE) use ultrasonic guided waves (GW) supported by active sensor technology to interrogate structural...

Published: 4/19/2022 | Inventor(s): Lingyu Yu, Zhaoyun Ma, Wenfeng Xiao, Zhenhua Tian

Keywords(s):

Category(s): Engineering and Physical Sciences