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Method for Vascular Regeneration and Wound Treatment

Asset/Technology Type Therapeutic Strategy Description of Invention The invention is a therapeutic approach for modulating cellular trans-differentiation and potentially angiogenesis by modulating O-glcnacylation (GlcNAc) of proteins, to treat various conditions. The inventors used existing small molecules to prove the concept in vitro and in vivo....

Published: 4/2/2025 | Inventor(s): John Cooke, Li Lai

Keywords(s):

Category(s): Clinical Area, Clinical Area > Cardiovascular, Research Area > Heart and Vascular, Research Area > Regenerative Medicine, Technology Classifications, Technology Classifications > Other

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 3/4/2025 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Development of Novel Natural Protein-Based Photo-Crosslinkable Hydrogel (Case No. 2020-440)

Summary: UCLA researchers from the Department of Bioengineering have developed a novel protein-based hydrogel that can be crosslinked with light for utility in a wide array of tissue engineering and regenerative applications. Background: Hydrogels are widely used in biomedical applications including 3D bioprinting and regenerative medicine. These...

Published: 2/20/2025 | Inventor(s): Mohammad Ali Darabi, Nureddin Ashammakhi, Ali Khademhosseini

Keywords(s):

Category(s): Materials, Materials > Functional Materials, Medical Devices

Fabrication Method for Hexagonal Boron Nitride Layers

Computer memory devices may employ any of various mechanisms for storing data, e.g., using memory cells each of which may be programmed to be in any of two or more states. Non-volatile memory includes memory cells each of which operates by changing the resistance across an active switching layer, e.g., an insulator, through the formation of conductive...

Published: 2/13/2025 | Inventor(s): Ivan Sanchez Esqueda, Jing Xie, Robert Nemanich, Ali Yekta

Keywords(s): Electronics, Fabrication, Materials and Electronics, Memory, Nanofabrication, Nanostructure, PS-Advanced Materials and Nanotechnology, Resistive Memory

Category(s): Advanced Materials/Nanotechnology, Physical Science, Semiconductors, Materials & Processes

Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations

The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...