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microCafe: Revolutionizing Genomic Analysis with Large Language Models
Analyzing metagenomic (DNA) and metatranscriptomic (RNA) sequence data is technically challenging and time-consuming. This process often necessitates assembly and mapping sequencing reads to existing databases of target genomic information; however, these databases are memory intensive and frequently limited in scope. Additionally, the mapping and assembly...
Published: 10/6/2025   |   Inventor(s): Ali Rahnavard, Keith Crandall
Keywords(s):  
Category(s): Technology Classifications > Research Tools
Spectral Kernel Machines With Electrically Tunable Photodetectors (Case No. 2025-105)
Summary: Spectral machine vision traditionally acquires dense 3D hypercubes (x, y, λ) of spatial and spectral information, which must be processed downstream. This imposes major computational burdens, tradeoffs in spatial/spectral resolution, frame rate, and power. The innovation embodied in spectral kernel machines (SKM) is a photodetector...
Published: 10/3/2025   |   Inventor(s): Aydogan Ozcan, Yuhang Li, Dehui Zhang, Ali Javey
Keywords(s):  
Category(s): Optics & Photonics, Materials, Materials > Nanotechnology, Materials > Functional Materials
AUTOMATED STRUCTURAL DAMAGE DETECTION AND LOCALIZATION USING MECHANICS-INFORMED DATA ANALYSIS
VAlue proposition Structural health monitoring ensures the safety and longevity of structures like buildings and bridges. As the volume and scale of structures and the impact of their failure continue to grow, there is a need for techniques that are scalable, inexpensive, can operate passively without human intervention, and are customized for each...
Published: 8/19/2025   |   Inventor(s): Vishnu Boddeti, Nizar Lajnef, Li Xuyang, Mahdi Masmoudi
Keywords(s):  
Category(s): Test and Measurement
Self-Healing Hardware for Perception Stage Faults in Autonomous Driving Systems
Autonomous Driving Systems (ADS) are safety-critical applications designed to enhance vehicle autonomy and general road safety. Perception, a critical stage of the pipeline, detects and classifies objects and environmental conditions. This stage is also highly susceptible to faults such as transient and permanent bit flips, which compromise the entire...
Published: 9/12/2025   |   Inventor(s): Guru Venkataramani, Ali Suvizi
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Computers Electronics & Software > Cybersecurity, Technology Classifications > Computers Electronics & Software > Computing Architecture
Broadband End-fed Coaxial Collinear Antenna Design
THE CHALLENGE The core challenge in today’s VHF/UHF antenna market lies in balancing high-performance technical requirements with practical business needs such as cost, durability, and ease of deployment. Existing antenna designs—like traditional coaxial collinear and dipole systems—often suffer from narrow bandwidth and unstable...
Published: 7/3/2025   |   Inventor(s): Majid Manteghi, Ali Hosseini-Fahraji
Keywords(s):  
Category(s): Technology Classifications > Computer Science, Technology Classifications > Electronics
Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use
" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are...
Published: 5/13/2025   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): Technologies
Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Campus, Campus > University at Albany
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 5/13/2025   |   Inventor(s): Li Niu, Zhen Huang, Yan Han, Congzhou Wang, Jae Seon Park
Keywords(s): RNA, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus, Campus > University at Albany
Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 5/13/2025   |   Inventor(s): Li Niu, Zhen Huang
Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
Method for Vascular Regeneration and Wound Treatment
Asset/Technology Type Therapeutic Strategy Description of Invention The invention is a therapeutic approach for modulating cellular trans-differentiation and potentially angiogenesis by modulating O-glcnacylation (GlcNAc) of proteins, to treat various conditions. The inventors used existing small molecules to prove the concept in vitro and in vivo....
Published: 5/21/2025   |   Inventor(s): John Cooke, Li Lai
Keywords(s):  
Category(s): Clinical Area, Clinical Area > Cardiovascular, Research Area > Heart and Vascular, Research Area > Regenerative Medicine, Technology Classifications, Technology Classifications > Other
Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 5/30/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
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