Search Results - xueling+wu

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

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Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Resurfaced Stabilized Core 3 (RSC3) Protein, Derived Proteins, and DNA Encoding These Proteins: RSC3, RSC3 delta371I, RSC3 delta371I/P363N, RSC3 G367R

Details for these materials may be found in the NIH AIDS Reagent Program Catalog – RSC3 (Catalog# 12042): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=214 RSC3 delta371I (Catalog# 12043): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=146 RSC3 delta371I/P363N (Catalog# 12362): https://www.aidsreagent.org/reagentdetail.cfm?t=proteins&id=145 RSC3...

Published: 8/13/2025 | Inventor(s): Tongqing Zhou, Gary Nabel, Zhi-yong Yang, Ling Xu, Peter Kwong

Keywords(s): 3, Core, DERIVED, DNA, Encoding, Protein, proteins, Resurfaced, RM, RSC3, Stabilized, THESE, WIXXXX

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials

Broadly Neutralizing Antibodies Against HIV-1 Directed to the CD4 Binding Site of HIV Envelope Protein

Inhibiting the ability of HIV-1, the virus that causes AIDS, to infect cells is one approach to both prevention and treatment of HIV. Scientists at the NIAID Vaccine Research Center have isolated and characterized neutralizing antibodies (VRC01, 02, 03, and 07) that bind to the CD4 binding site of HIV-1 envelope glycoprotein gp120. These human monoclonal...

Published: 8/13/2025 | Inventor(s): Richard Wyatt, Xueling Wu, Yuxing Li, Carl-Magnus Hogerkorp, Mario Roederer, Zhi-yong Yang, Gary Nabel, Peter Kwong, Tongqing Zhou, Mark Connors, Gilad Ofek, Yongping Yang, Jiang Zhu, Lawrence Shapiro, William Schief, Rebecca Rudicell, Ivelin Georgiev, Young Do Kwon, Baoshan Zhang, Gwo-yu Chauang, Wei Shi, Gwo-Yu Chuang, John Mascola

Keywords(s): Against, antibodies, Antibodies., ANTIBODY, Antibody-based, B-Cells, Broadly, Chain, Constructs, CREATION, DA4AXX, DB4AXX, DC5AXX, DD2XXX, Epitope-Specific, Expressing, FUNCTION, Further, GENERAL, GLYCOPROTEIN, gp120, HIV, HIV-1, Identity, Immunoadesion, Immunoadhesin, Isolation, Listed LPM Thalhammer-Reyero as of 4/15/2015, MODE, Modifications, monoclonal, Monoco, Neutizing, Neutralization, Neutralizing, Novel, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Probes, Single, Specific, VRC03, VRC03Isolation

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Research Materials

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

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Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 1/9/2026 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

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Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

THIN DIELECTRIC COATED PLASMONIC PHOTOEMITTER

VALUE PROPOSITION The Thin Dielectric Coated Plasmonic Photoemitter is a prescribed coating of a metal nano emitter with a dielectric material resulting in optical enchantments when pulsed by an ultra-fast laser. This new technology allows for an expansion in the electric laser field, by adding a thin dielectric coating to the nanotip. The image resolution...

Published: 11/11/2024 | Inventor(s): Peng Zhang, Lin Wu, Xiao Xiong, Yang Zhou

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Category(s): Advanced Materials, Devices, Nanotechnology

Functional Nanoglues for Stable Metal Single-Atom and Cluster Catalysts

Background Recent advances in catalysis by single-atom catalysts (SACs) and cluster catalysts have highlighted the unique catalytic properties of highly dispersed metal species. The use of single metal atoms or small clusters for catalysis is not only cost-effective but also significantly enhances the selectivity of a targeted reaction, resulting in...

Published: 2/13/2025 | Inventor(s): Jingyue Liu, Xu Li

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Environmental, Environmental Remediation/Wastewater Treatment, Physical Science

Multilayer Batch Microfabricated Magnetic Shielding

UCLA Case No. 2018-014 SUMMARYUCLA researchers in the Department of Electrical Engineering have developed a novel batch microfabrication technique for microscale shielding layers, simultaneously pushing the limits of minimum size, maximum shielding factor, flexibility, and cost.BACKGROUNDCompact electromagnetic shielding paves the way for a new generation...

Published: 7/17/2025 | Inventor(s): Robert Candler, Jimmy Chen-Yen Wu, Ling Li, Jere Harrison

Keywords(s): Electronics & Semiconductors

Category(s): Electrical > Electronics & Semiconductors, Materials > Fabrication Technologies

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