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Search Results - wen+fang+liu
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Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 9/13/2024
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Inventor(s):
Wen Li
,
Hasan Banna
,
James Siegenthaler
Keywords(s):
Category(s):
Agriculture
,
Analytical Instruments
,
Environment
,
Test and Measurement
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 6/5/2024
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Inventor(s):
Li Liu
,
Jingmin Shu
Keywords(s):
Category(s):
Applied Technologies
,
Genomic Assays/Reagents/Tools
,
Life Science (All LS Techs)
,
Diagnostic Assays/Devices
Peptide Mimetic Ligands of Polo-like Kinase 1 Polo Box Domain (“Plk1 PBD Portfolio”)
Abstract: Polo-like kinase 1 (Plk1) is a critical protein involved in regulation of mitosis, and aberrant expression of this kinase is found in various cancer types. Inhibition of Plk1 is currently being pursued in pre-clinical drug development for novel anti-cancer therapeutics. Plk1 contains an allosteric domain, known as the polo-box domain (PBD),...
Published: 5/22/2024
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Inventor(s):
Terrence Burke
,
Jung-Eun Park
,
Wen-Jian Qian
,
Fa Liu
,
Kyung Lee
Keywords(s):
Burke
,
CANCER
,
mitosis
,
Peptide Inhibitor
,
polo-box domain (PBD)
,
Polo-like kinase 1 (Plk1)
,
therapeutic
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Therapeutics
A New Mouse Monoclonal Antibody Against Human Microphthalmia Transcription Factor (MITF)
Micropthalmia Transcription Factor (MITF) plays an important role in melanocyte development and melanoma growth. MITF is important for embryonic development, regulating the generation of pigment cells and formation of melanomas and other tumors. MITF is made in various isoforms that may play unique roles for different organs during different developmental...
Published: 4/8/2024
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Inventor(s):
Wen Fang Liu
,
Hideki Murakami
,
Heinz Arnheitter
Keywords(s):
ANTIBODY
,
CANCER
,
CC2XXX
,
CCXXXX
,
CXXXXX
,
factor
,
Human
,
Microphthalmia
,
MITF
,
monoclonal
,
Mouse
,
RELATED
,
transcription
Category(s):
Collaboration Sought > Licensing
,
Collaboration Sought > Materials Available
,
TherapeuticArea > Oncology
,
Application > Research Materials
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
JobViz: User Interface for Visualization of Majors & Jobs
Invention Summary: University (and industry) career search portals and web-based job search engines allow users to search on many items (e.g., education, location, level, etc.) and then present a text based list of potential job opportunities. University career portals are not as conductive to exploration by job and career searchers as they could...
Published: 9/8/2022
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Inventor(s):
Deborah Silver
,
Li Liu
Keywords(s):
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
Monolithic White and Multi-Color Lasers Tunable in Full Visible Spectrum
Semiconductor lasers able to emit over the full visible color spectrum have a wide range of practical applications such as solid-state lighting, full-color displays, visible color communications, and multi-color fluorescence sensing. To the human eye, light with a mixture of four monochromatic lasers is visually equivalent to a white illuminant. Current...
Published: 2/23/2023
|
Inventor(s):
Cun-Zheng Ning
,
Sunay Turkdogan
,
Zhicheng Liu
,
Fan Fan
Keywords(s):
Materials and Electronics
Category(s):
Advanced Materials/Nanotechnology
,
Chemical/Biological Sensors
,
Energy & Power
,
Imaging
,
Medical Imaging
,
Physical Science
,
Physics
,
Proteomic Assays/Reagents/Tools
,
Semiconductor Devices
,
Semiconductors, Materials & Processes
Fuel Cell With Dynamic Response Capability Based On Energy Storage Electrodes
UC Case No. 2017-231SUMMARYUCLA researchers in the Department of Chemical Engineering have developed fuel cells with energy-storage capabilities.BACKGROUNDCurrent fuel cell technologies are limited by cost and lifetime, as well as poor response to operating condition fluctuations. Adding energy storage devices to fuel cells can improve their dynamic...
Published: 7/19/2023
|
Inventor(s):
Yunfeng Lu
,
Jing Liu
,
Gurong Shen
,
Fang Liu
,
Haobin Wu
,
Jinlai Li
,
John Lemmon
Keywords(s):
Energy & Water
Category(s):
Energy & Environment > Energy Storage
,
Energy & Environment > Energy Storage > Fuel Cells
Implantable Neural Microelectrodes and Fabrication Method
Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...
Published: 2/17/2023
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Inventor(s):
Wen Li
,
Yue Guo
,
Thomas Schuelke
,
Michael Becker
,
Robert Rechenberg
,
Cory Rusinek
Keywords(s):
Category(s):
Advanced Materials
,
Biotechnology
,
Devices
Flexible Hybrid Diamond Biosensor
Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...
Published: 6/8/2021
|
Inventor(s):
Wen Li
,
Bin Fan
,
Michael Becker
,
Robert Rechenberg
Keywords(s):
Category(s):
Advanced Materials
,
Devices
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