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A lung-targeting britannin-lipid nanoparticle formulation and use thereof
This technology is a novel lung-targeting britannin-lipid nanoparticle formulation designed to effectively treat acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) by inhibiting lung inflammation. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe lung conditions characterized by intense...
Published: 6/12/2026   |   Updated: 6/11/2026   |   Inventor(s): Yamin Li, Qinghe Meng, Daping Fan
Keywords(s): acute lung injury, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
Rapid, Low-Cost Point-of-Care Test for Cerebrospinal Fluid Leak Detection
Enables Bedside Detection of β-2-Transferrin Using a Silicon MOSFET Sensor This low-cost, disposable test strip electrically detects β-2-transferrin (β2T), a highly specific protein marker for cerebral spinal fluid (CSF) leakage. Cerebral spinal fluid leaks are a serious medical condition resulting from trauma, surgery, or spontaneous...
Published: 6/18/2026   |   Updated: 5/22/2026   |   Inventor(s): Marino Leon, Brian Lobo, Stephen Pearton, Fan Ren, Yu-Te Liao
Keywords(s):  
Category(s): Technology Classifications > Human Health Care
Ultra-Smooth Single-Crystal Diamond Surfaces for Enhanced Device Performance
Reduces Surface Roughness and Spike Density Through Extended UV-Ozone Exposure This diamond smoothing method via extended UV-ozone exposure enhances device performance and reliability by reducing surface roughness and spike density. Diamond-based devices, such as rectifiers, offer significant potential for high-power and high-frequency applications....
Published: 6/4/2026   |   Updated: 4/16/2026   |   Inventor(s): Fan Ren, Chao-Ching Chiang, Stephen Pearton
Keywords(s):  
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Electrical, Technology Classifications > Engineering, Technology Classifications > Engineering > Materials
APEX: Efficient LLM Inference on Low-Memory GPUs
THE CHALLENGE Deploying large language models efficiently has become a major business obstacle as GPU memory limitations increasingly drive-up infrastructure costs and restrict scalability. During inference, the rapid growth of the key value cache consumes GPU memory quickly, limiting batch sizes and output lengths and reducing overall system throughput....
Published: 3/31/2026   |   Updated: 3/31/2026   |   Inventor(s): Jiakun Fan, Dimitrios Nikolopoulos
Keywords(s):  
Category(s): Technology Classifications > Computer Science
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 6/17/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Membrane-less, Gravity Independent Liquid-Liquid and Gas-Liquid Extraction and Phase Separation
A membrane-less device enabling liquid-liquid and gas-liquid separation without requiring gravity Background The separation of mixtures of fluid phases, particularly liquid-liquid and gas-liquid extraction, is relevant to many industrial chemical and biochemical processes, including fuels production, pharmaceuticals, and hydrometallurgy. Many solvent...
Published: 4/16/2026   |   Updated: 3/18/2026   |   Inventor(s): Goran Jovanovic, Matthew Coblyn, Jad Touma, Lucas Freiberg, Francis Chukwunta, Lei Li, Cliff Kowall, Bingchen Wang, Yihan Song, Fan Yang, Aigerim Baimoldina
Keywords(s):  
Category(s): Engineering
Anodization Tool for Uniform Titanium Oxide Nanotubes on Non-Conductive Surfaces, Enabling Advanced Dental Implants and Biomedical Devices
Produces Titanium Oxide Nanotubes, Enhancing Dental Implants with Antibacterial and Biocompatible Properties Dental implants and other load-bearing biomedical devices rely heavily on surface properties to achieve long-term stability, osseointegration, and resistance to bacterial colonization. These are important aspects of modern dentistry that impact...
Published: 4/13/2026   |   Updated: 3/16/2026   |   Inventor(s): Josephine Esquivel-Upshaw, Fan Ren, Chao-Ching Chiang
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 6/17/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Enhanced High Efficiency Zinc-Air Batteries
Invention Description Zinc-air batteries (ZABs) consist of cells that use metallic zinc as the anode, atmospheric oxygen as the cathode and water‑based electrolytes. These batteries have a large appeal due to their low-cost production, sustainable approach (less reliance on rare/toxic metals), and solution for large-scale and slow-cycle energy storage....
Published: 2/26/2026   |   Updated: 11/4/2025   |   Inventor(s): Zhaoyang Fan
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Energy & Power, Physical Science
Advancing High-Throughput Diagnostics With Wash-Free Programmable Toehold Fluorescence Imaging
Streamlines Fluorescence Imaging by Eliminating Buffer Exchanges for Faster Target Analysis This wash-free multiplexed fluorescence bio-imaging aims to revolutionize fluorescence imaging by overcoming the limitations of traditional workflows with programmable toehold probes in situ. Conventional imaging techniques often require time-intensive buffer...
Published: 2/4/2026   |   Updated: 10/9/2025   |   Inventor(s): Fan Hong, Tingyi Zhu
Keywords(s):  
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Human Health Care > Diagnostics
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