Search Results - quantitative

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Real-time PCR Assays for Human Bocavirus Detection and Diagnosis
CDC researchers have developed a real-time PCR assay for the detection and viral-load quantitative estimations of human bocavirus (HBoV) from clinical specimens. At present, there have been few reports on the epidemiology, geographic distribution or clinical features of HBoV infection. Additionally, symptoms affiliated with bocavirus infections overlap...
Published: 4/8/2024   |   Inventor(s): Teresa Peret, Dean Erdman
Keywords(s): Bocavirus, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4XXX, DAXXXX, DXXXXX, Human, NAT, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, OID-NCIRD-DVD, Processes, QUANTITATIVE, real time, Realtime, REAL-TIME, Relating, respiratory, Respiratory Diseases, respiratory INFECTION, viral, VIRAL DIAGNOSTIC, VLXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Dental, Application > Diagnostics, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Oncology
Real-time RT-PCR Assay for the Detection of Rift Valley Fever Virus in Humans and Livestock
A quantitative RT-PCR-based assay has been developed to rapidly detect all known strains of Rift Valley fever virus (RVFV). RVFV infections occur in both humans and livestock animals resulting in significant mortality and economic loss. Upon outbreak, RVFV has been known to cause devastating loss among livestock (primarily sheep and cattle) with outbreaks...
Published: 10/28/2024   |   Inventor(s): Stuart Nichol, Brian Bird
Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DDXXXX, Diagnosis, DXXXXX, FEVER, Kits, Methods, Pan-Rift, QUANTITATIVE, REAL-TIME, RT-PCR, Valley, VBXXXX, virus, VLXXXX, VOXXXX, WAXXXX, WDXXXX, WFXXXX, WIXXXX, WMXXXX, XEXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Vaccines, Application > Therapeutics
Real-time RT-PCR Assay For Detection and Quantification of Hepatitis D Virus Infection
CDC scientists have developed a one-step TaqMan quantitative/real-time reverse transcription-polymerase chain reaction (qRT-PCR) assay for detecting hepatitis D virus (HDV) RNA. Additionally, a quantifiable synthetic RNA control to determine viral load has been created. HDV is an operatively defective virus that requires hepatitis B virus (HBV) surface...
Published: 10/28/2024   |   Inventor(s): Tonya Mixson-Hayden, Saleem Kamili, Maja Kodani
Keywords(s): assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, cirrhosis, D, DA4BXX, DA4XXX, DAXXXX, Detection, diagnostic, Diagnostic assay, DXXXXX, HBV, HDV, Hepatitis, HEPATITIS B, liver, liver disease, Liver disorders, Liver-Disease, OID-NCHHSTP-DVH, PCR, QUANTITATIVE, REAL, real time, REAL-TIME, RT-PCR, viral, virus
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease
Modified Peptide Nucleic Acids (PNAs) for Detection of DNA or RNA and Identification of a Disease or Pathogen
The NIH announces a novel method for fast, simple, and accurate detection of nucleic acids outside the modern laboratory. Nucleic acid testing is highly specific and often provides definitive identification of a disease or pathogen. Methods to detect nucleic acid sequences and identify a disease or pathogen are dominated by PCR, but applying PCR-based...
Published: 10/28/2024   |   Inventor(s): Christopher Micklitsch, Bereket Yemane (formerly Oquare), Chao Zhao, Daniel Appella
Keywords(s): Acids, Cyclopentane-Peptide, DAXXXX, Detection, DXXXXX, Nucleic, Qualitative, QUANTITATIVE, YXXXXX
Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Infectious Disease
Simple, Quantitative Sensitive High-throughput Antibody Detection for Lyme Disease
This technology is for compositions and methods for diagnosis of Lyme disease. Currently, Lyme disease is diagnosed by clinical exam and a history of exposure to endemic regions. Although, laboratory tests may aid diagnosis, the best tests currently available are slow and labor intensive and require understanding of the test, and infection stage....
Published: 10/28/2024   |   Inventor(s): Adriana Marques, Michael Iadarola, Peter Burbelo
Keywords(s): ANTIBODY, Borreliosis, DAXXXX, Detection, Disease, DXXXXX, Highly, Listed LPM Fenn as of 4/15/2015, LYME, Lyme Disease, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, QUANTITATIVE, SENSITIVE, SIMPLE, VJXXXX, WBXXXX
Category(s): TherapeuticArea > Infectious Disease, Application > Diagnostics
Antigens for Use in Loa Loa Microfilariae Quantitative Immunoassays
Loa loa microfilarial-specific peptide sequences that could be used as a research material as well as for development of immunoassays for detection of Loa loa microfilaremia.
Published: 10/28/2024   |   Inventor(s): Papa Drame, Sasisekha Bennuru, Thomas Nutman
Keywords(s): ANTIGENS, IMMUNOASSAYS, Listed LPM Fenn as of 4/15/2015, Loa, Microfilariae, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, QUANTITATIVE, RM, VQXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials, TherapeuticArea > Infectious Disease
Neuropsychological digital assessment test that identifies discrete latencies in response time to identify emergent neurological/nueropsychiatric illness
TechnologyDeclining cognitive health is increasing in the U.S and worldwide. Early detection of impairment is crucial to altering the course of disease. Many cognitive assessments have previously focused on early memory defects, such as those associated with Alzheimer’s, and it is now evident that focused deficits accumulate over several decades...
Published: 3/6/2024   |   Inventor(s): David Libon, Ganesh Baliga, Mary Kerwin, Rod Swenson
Keywords(s): Alzheimer's, Assesments, Cognition, Dementia, Intervention, Neurodegeneration, Quantitative
Category(s): Research Tools, Software, Human Health Care > Biomarkers, Diagnosis and Detection