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Advancement in Platinum Based Cancer Therapeutics
Project ID: D2013-02 Novelty: Small drug like molecules that inhibits DNA repair factors for cisplatin (and other platinum based drugs) resistance towards solid tumors, thereby increasing cisplatin cytotoxicity and efficacy. Value proposition: One of the limitations of chemotherapy in ovarian cancer is the innate/acquired drug resistance in cancer...
Published: 1/2/2025   |   Inventor(s): Stephan Patrick, Paul Erhardt
Keywords(s): Cisplatin, Clinical Trials, DNA Repair, Ovarian Cancer, Platinum
Category(s): Oncology
Optical Fiber Reactor for Gas Treatment of Nitrogen-Oxide
Background Nitrogen oxides (NOx) as well as nitrous oxide (N2O) have been identified as pollutants of concern in the semiconductor manufacturing industry. While there has been successful implementation of abatement systems to control the emissions of nitrogen oxides, some facilities require further removal to comply with new regulations and meet sustainability...
Published: 12/16/2024   |   Inventor(s): Pierre Herckes, Paul Westerhoff, Matthew Fraser
Keywords(s):  
Category(s): Physical Science, Semiconductors, Materials & Processes, Energy & Power, Environmental
Photoelectrocatalytic-Enabled Flexible Polymeric Optoelectrodes
Background Photoelectrocatalytic processes (PECs) combine photocatalysis and electrochemical principles to enhance charge carrier generation and stability within nanomaterials (NMs). Nano-enabled PECs can be used for water purification or hydrogen production applications. Current PEC designs face challenges due to low energy efficiencies, because most...
Published: 12/13/2024   |   Inventor(s): Paul Westerhoff, Sergi Garcia-Segura, Tzu-Heng Wang
Keywords(s):  
Category(s): Physical Science, Advanced Materials/Nanotechnology, Energy & Power, Environmental Remediation/Wastewater Treatment
Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations
The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Planner – Planning Software for Near-Earth Object Survey Operations
The Planner subsystem in the Catalina Sky Survey (CSS) software suite is designed to help observers efficiently plan nightly asteroid and Near-Earth Object (NEO) observations. By displaying a virtual map of the sky, it helps ensure that areas previously searched, or areas unlikely to be productive, are avoided. The map shows the telescope’s current...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Processing – Software to Process and Analyze Images for NEO Survey
The Processing subsystem in the Catalina Sky Survey (CSS) software suite is a streamlined pipeline designed to handle raw images captured by telescopes during asteroid and Near-Earth Object (NEO) surveys. This pipeline processes the images through multiple stages, such as calibrating for optical distortions, extracting star or asteroid positions, and...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Monitor – Software to Monitor Status of New and Recently Discovered Objects for NEO Survey
The Monitor subsystem in the Catalina Sky Survey (CSS) software suite is designed to help track the status of newly discovered and recently observed asteroids and Near-Earth Objects (NEOs). It gathers data from various public sources, such as the Minor Planet Center and other NEO survey programs, to provide a clear and prioritized summary of which objects...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Software & Information Technology
Control - An Executive Program for Near-Earth Object Survey Operations
The Catalina Sky Survey (CSS) software suite is designed to detect and track Near-Earth Objects (NEOs), such as asteroids, that may pose a collision risk with Earth. By coordinating observations and data processing through multiple subsystems, the suite enables accurate tracking of these objects. The software manages telescope operations, image acquisition,...
Published: 12/9/2024   |   Inventor(s): A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology, Technology Classifications > Software & Information Technology > Open Source
Machine Learning Model for the Prioritization of Cancer Neoepitopes
Summary: The National Cancer Institute (NCI) seeks licensees for a machine learning algorithm that scores epitopes for likelihood of reactivity in order to create personalized effective immunotherapy. Description of Technology: Success in immunotherapy is often attributable to the reactivity of patient T-cells to specific mutated peptide(s) found...
Published: 12/20/2024   |   Inventor(s): Jared Gartner, Paul Robbins, Steven Rosenberg
Keywords(s):  
Category(s): Application > Research Materials, TherapeuticArea > Oncology, Collaboration Sought > Licensing
High-Efficiency Photocatalytic Formate Production from Carbon Dioxide
Background Greenhouse gases (GHGs) trap heat and lead to global warming and other severe effects of climate change. Carbon dioxide (CO2) is the main source of GHG, and its capture before entering the atmosphere is an important mitigation approach. Captured CO2 from point-emission sources or via direct air capture (DAC) can be geologically sequestered...
Published: 11/15/2024   |   Inventor(s): Yen-Jung Lai, Tzu-Heng Wang, Paul Westerhoff, Bruce Rittmann
Keywords(s):  
Category(s): Physical Science, Energy & Power, Environmental
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