Search Results - paolo+lusso

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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Monoclonal Antibodies To Prevent or Treat SARS-CoV-2 Infection
The ongoing COVID-19 pandemic, caused by severe respiratory syndrome coronavirus 2 (SARS-CoV-2), has created an immense public health, social, and economic burden. Variants of concern continue to emerge that have increased transmissibility, pathogenicity, or both and that reduce the effectiveness of current therapeutics and vaccines. Thus, there is...
Published: 10/28/2024   |   Inventor(s): Patrizia Farci, Kamille West, Peng Zhang, Paolo Lusso, Zhaochun Chen
Keywords(s): antibodies, Cure, Disease, monoclonal, Prevent, SARS-CoV-2
Category(s): Collaboration Sought > Collaboration
Recombinant Sulfated HIV Envelope Protein and Methods for Making Protein
This technology comprises sulfated recombinant gp120 proteins and peptides. Also included are methods for producing sulfated recombinant gp120 proteins. The focus of this technology is on sulfation of two tyrosines in the V2 loop of the HIV major envelope glycoprotein, gp120, which increase the stability of gp120 and promote the synthesis of gp120 protein...
Published: 10/28/2024   |   Inventor(s): Raffaello Cimbro, Paolo Lusso
Keywords(s): BETWEEN, CD4, DB4XXX, DBXXXX, DC5XXX, DCXXXX, DXXXXX, Envelope, gp120, HIV, INHIBIT, INTERACTION, Mimics, Peptide, Protein, RECEPTOR, That, V2-loop, VLXXXX, WIXXXX, WJXXXX, WKXXXX, YAXXXX, YBXXXX, YCXXXX, YFXXXX
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Therapeutics, Application > Vaccines
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology