Search Results - patrizia+farci

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TACSTD2 in HCV Infection and Hepatocellular Carcinoma: Transcriptomics Insights
This technology involves studying the role of the Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) gene in Hepatitis C Virus (HCV) infection and hepatocellular carcinoma. Researchers perform transcriptomics analysis on liver specimens from HCV-infected patients, identify TACSTD2 as a key gene, and create a stable cell line that overexpresses TACSTD2...
Published: 12/10/2024   |   Inventor(s): Patrizia Farci, Vandana Sekhar
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease
Monoclonal Antibodies To Prevent or Treat SARS-CoV-2 Infection
The ongoing COVID-19 pandemic, caused by severe respiratory syndrome coronavirus 2 (SARS-CoV-2), has created an immense public health, social, and economic burden. Variants of concern continue to emerge that have increased transmissibility, pathogenicity, or both and that reduce the effectiveness of current therapeutics and vaccines. Thus, there is...
Published: 10/28/2024   |   Inventor(s): Patrizia Farci, Kamille West, Peng Zhang, Paolo Lusso, Zhaochun Chen
Keywords(s): antibodies, Cure, Disease, monoclonal, Prevent, SARS-CoV-2
Category(s): Collaboration Sought > Collaboration
Tumor Associated Calcium Signal Transducer 2 (TACSTD2)-Overexpressing Huh7.5 Cells That Are More Permissive to HCV Cell Entry and Replication Compared to the Model Huh7.5 Cell Line
Worldwide, 130-150 million individuals are chronically infected with hepatitis C virus (HCV), a major cause of liver-associated morbidity and mortality worldwide. Despite recent advances in antiviral drugs that can cure some individuals, a rapid decline of the global disease burden is hampered by remarkably high treatment costs and a high number of...
Published: 10/28/2024   |   Inventor(s): Vandana Sekhar, Patrizia Farci
Keywords(s): 2, Associated, CALCIUM, Cells, Huh7.5, Signal, TACSTD2-overexpressing, TRANSDUCER, tumor
Category(s): Collaboration Sought > Licensing