Search Results - lu+lu

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Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 7/31/2025   |   Inventor(s): Yi Lu, Yu Zhou
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
DNA-based sensors for live-cell mapping of metabolite- and metal ion-protein interactions
Background Understanding how metabolites and metal ions interact with proteins inside living cells is essential for decoding cellular signaling, metabolic regulation, and disease mechanisms. These small molecules function as cofactors, second messengers, and allosteric regulators, orchestrating critical pathways that govern cell behavior. However,...
Published: 6/16/2025   |   Inventor(s): Yi Lu, Mandira Banik
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
Artificial nitrogenase enzymes for ambient-condition, decentralized ammonia production
Background Ammonia synthesis is foundational to global agriculture and chemical manufacturing, providing the primary source of fixed nitrogen for fertilizers, polymers, and pharmaceuticals. Traditional ammonia production through the Haber-Bosch process, however, operates under extreme conditions—temperatures exceeding 400°C and pressures...
Published: 7/2/2025   |   Inventor(s): Yi Lu, Hirbod Heidari, Markus Ribbe, Yilin Hu, Chi Chung Lee, Evan Mirts
Keywords(s):  
Category(s): Life sciences > Therapeutics > Synthetic biology, Life sciences > Metabolic engineering
Dynamic-based Computational Drug Design Strategy for WW Domains
Understanding the relationship between protein sequence-structure and binding dynamics is not well understood. Of particular interest is the ability to relate foldability and function of a protein and the ability to characterize how foldability and binding change based on mutations in the protein sequence. WW domains are one of the most abundant independently...
Published: 6/3/2025   |   Inventor(s): Jin Lu, Ismail Can Kazan, Sefika Banu Ozkan
Keywords(s):  
Category(s): Artificial Intelligence/Machine Learning, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Real-Time Program-Specific Log Consolidation for Intrusion Detection
Advantages Reduces logs 219× for efficient data storage Performs real-time analysis with zero offline cost Minimizes memory use through subject activity consolidation Maintains high detection accuracy with low alert fatigue Summary Enterprises today are increasingly targeted by Advanced Persistent Threats (APTs), stealthy, long-term attacks...
Published: 7/18/2025   |   Inventor(s): Yao Liu, Xiao Han, Zhuo Lu
Keywords(s): Computer Science, Cybersecurity
Category(s): Technology Classifications > Computer Science > C/S Cybersecurity, Technology Classifications > Computer Science > Algorithms, Technology Classifications > Computer Science > Computers Software & Information Technology, Technology Classifications > Computer Science > Datasets
Nano-Biocatalytic Membranes for Water Treatment
Multi-functional membrane to prevent biofouling during water purification processes Background: As the need for more sources of drinkable water increases, there is a strong interest in developing more advanced water purification technologies. During long term use, water purification membranes are susceptible to biofilm formation, clogging the membranes,...
Published: 5/21/2025   |   Inventor(s): Appala Badireddy, Huijie Lu
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Environment & Energy
Simple Serological Pan Bacterial Diagnostic
Antimicrobial resistance is one of the biggest global health crises we are currently facing, and it is being accelerated by the overuse and misuse of antibiotics. There is a tendency, especially in pediatrics, to prescribe antibiotics for viral infections, or to withhold an antibiotic out of an abundance of caution. A contributing factor in antibiotic...
Published: 4/28/2025   |   Inventor(s): Stephen Johnston, Lu Wang
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Proteomic Assays/Reagents/Tools
Glanceability in Augmented Reality Systems
THE CHALLENGE Challenge in developing head-worn augmented reality (AR) devices lies in creating systems that can deliver timely, context-aware digital content without disrupting the user’s primary tasks. While there is strong market demand for hands-free, real-time information access—especially in sectors like manufacturing, healthcare,...
Published: 7/9/2025   |   Inventor(s): Doug Bowman, Feiyu Lu, Wallace Santos Lages, Shakiba Davari-Najafabadi, Lorance Lisle, Yuan Li
Keywords(s):  
Category(s): Technology Classifications > Consumer Products
Precision cellular imaging for advanced biological analysis
A novel DNA-based imaging technique enabling visualization of 3D cellular components with super-resolution. Background Super-resolution microscopy has revolutionized biological research by providing finer details beyond the diffraction limit of conventional microscopy. A particular challenge in this field is the visualization of small and dynamic...
Published: 3/4/2025   |   Inventor(s): Yi Lu, Quanbing Mou
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Research tools > Tool/assay/screening platform
A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo
Heart disease is among the most challenging human diseases to diagnose and treat, and it remains the leading cause of mortality worldwide. Its complex underlying pathophysiology has driven the development of advanced techniques to study heart function during sinus rhythm, dysfunction, and treatment. There is growing interest in combining electrical...
Published: 7/28/2025   |   Inventor(s): Igor Efimov, Luyao Lu
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Medical Devices > Diagnostic Devices, Technology Classifications > Medical Devices > Surgical
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