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Search Results - lu+lu
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Glanceability in Augmented Reality Systems
THE CHALLENGE All-day wearable augmented reality (AR) devices, particularly smart glasses, will be increasingly available in the near future, revolutionizing the way people live and work. Impediments limiting further adoption are not only related to hardware, but also to insights surrounding presentation and interaction with virtual information. OUR...
Published: 4/9/2025
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Inventor(s):
Doug Bowman
,
Feiyu Lu
,
Wallace Santos Lages
,
Shakiba Davari-Najafabadi
,
Lorance Lisle
,
Yuan Li
Keywords(s):
Category(s):
Technology Classifications > Consumer Products
Precision cellular imaging for advanced biological analysis
A novel DNA-based imaging technique enabling visualization of 3D cellular components with super-resolution. Background Super-resolution microscopy has revolutionized biological research by providing finer details beyond the diffraction limit of conventional microscopy. A particular challenge in this field is the visualization of small and dynamic...
Published: 3/4/2025
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Inventor(s):
Yi Lu
,
Quanbing Mou
Keywords(s):
Category(s):
Life sciences > Imaging
,
Life sciences > Research tools > Tool/assay/screening platform
A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo
Heart disease is among the most challenging human diseases to diagnose and treat, and it remains the leading cause of mortality worldwide. Its complex underlying pathophysiology has driven the development of advanced techniques to study heart function during sinus rhythm, dysfunction, and treatment. There is growing interest in combining electrical...
Published: 2/18/2025
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Inventor(s):
Igor Efimov
,
Luyao Lu
Keywords(s):
Category(s):
Technology Classifications > Medical Devices > Cardiology
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Technology Classifications > Medical Devices > Diagnostic Devices
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Technology Classifications > Medical Devices > Surgical
DNAzyme sensor for selective manganese ion detection in biological systems
A selective DNAzyme-based fluorescent sensor detects manganese ions in cells by lighting up when Mn²⁺ binds, allowing precise monitoring of manganese levels for biological research and potential therapies. Background Manganese (Mn²⁺) is an essential trace element integral to numerous biological processes, acting as a vital cofactor for enzymes...
Published: 1/31/2025
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Inventor(s):
Yi Lu
,
Zhenglin Yang
,
Huanhuan Fan
Keywords(s):
Category(s):
Life sciences > Biomaterials
DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions
Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...
Published: 1/31/2025
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Inventor(s):
Yi Lu
,
Seyed-Fakhreddin Torabi
,
Yuting Wu
,
Ryan Lake
,
Zhenglin Yang
,
Peiwen Wu
,
Whitney Lewis
,
Jacqueline Van Stappen
,
Xiangli Shao
Keywords(s):
Category(s):
Life sciences > Biomaterials
Defending Against Wi-Fi Spoofing Attacks Leveraging Physical-Layer Features
Advantages: Identifies Wi-Fi spoofing attacks by leveraging Doppler Effect and Symbol Timing Offset (STO) variations Protects against location manipulation, ensuring accurate navigation even in high-risk environments Improves navigation accuracy by differentiating legitimate and spoofed signals Cost-effective implementation with off-the-shelf...
Published: 1/22/2025
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Inventor(s):
Xiao Han
,
Yao Liu
,
Zhuo Lu
Keywords(s):
Autonomous Vehicle
,
Cybersecurity
,
Telecommunication / Wireless Communication
,
Transportation
Category(s):
Technology Classifications > Computer Science > C/S Cybersecurity
,
Technology Classifications > Computer Science > Algorithms
DNA aptamer technology for Coenzyme A detection and cellular imaging
Researchers developed a DNA aptamer that specifically targets Coenzyme A, enabling easy and accurate detection in cells. This technology is more specific and simpler than current methods, supporting diagnostics, research, and treatments for diseases involving CoA imbalance. Background The field of biochemical research and medical diagnostics increasingly...
Published: 1/14/2025
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Inventor(s):
Yi Lu
,
Whitney Lewis
,
Yuan Ma
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug screening
,
Life sciences > Research tools > Tool/assay/screening platform
Highly sensitive pressure sensor for diverse applications
A flexible, highly sensitive pressure sensor combines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025
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Inventor(s):
Nanshu Lu
,
Kyoung-Ho Ha
Keywords(s):
Category(s):
Life sciences > Medical technology
Degrader Molecules for hRpn13Pru, PCLAF, RRM2 and Other KEN Box-containing Proteins
Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for three small molecules that target hRpn13, an overexpressed protein in certain cancers. Description of Technology: Over 35,000 new cases of multiple myeloma are diagnosed each year in the US. Standard of care and experimental therapies include...
Published: 12/20/2024
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Inventor(s):
Kylie Walters
,
Xiuxiu Lu
Keywords(s):
Category(s):
Application > Therapeutics
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
,
Collaboration Sought > Licensing
Modified kynureninase enzymes for cancer therapy
This invention describes modified kynureninase enzymes, particularly human enzymes, for degrading kynurenine. These enzymes can be used in compositions and methods for treating cancer by depleting kynurenine levels. Background Cancer immunotherapy has emerged as a promising approach to treating a wide range of malignancies. The goal of immunotherapy...
Published: 11/5/2024
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Inventor(s):
George Georgiou
,
Everett Stone
,
John Blazeck
,
Nicholas Marshall
,
Wei-Cheng Lu
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
,
Life sciences > Therapeutics > Gene therapy
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