Search Results - obstetric%2fgynecological

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A New Adjustable Applicator for Interstitial Brachytherapy
NU 2022-153 INVENTORS Shuhua Zheng* Jonathan Strauss Eric Donnelly Jooyoung Sohn SHORT DESCRIPTION A new and improved brachytherapy applicator for treating patients with gynecological cancers. This advanced device allows for precise, visualized placement of interstitial implants to improve therapeutic outcomes. ABSTRACT Gynecologic cancers, particularly...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Medical device, Obstetric/Gynecological
Category(s): Life Sciences > Therapeutics
Small Molecule Inhibitors of Tissue Transglutaminase for Cancer Therapy
NU 2020-020 INVENTORS Gary E. Schiltz Daniela E. Matei* Purav Vagadia SHORT DESCRIPTION A novel series of small molecule inhibitors that suppress metastasis and sensitize cancer cells to standard cytotoxic therapy BACKGROUND Tissue transglutaminase (TG2) is a multifunctional protein that interacts with fibronectin (FN) and is highly expressed in...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Obstetric/Gynecological, Therapeutics
Category(s): Life Sciences > Therapeutics
An Automated Fluidic Plate System for Culturing Multiple Cell Types
NU 2016-207BInventorsTeresa Woodruff*Hunter RogersShort DescriptionLaboratory automation compatible fluidic culture platform for drug discovery BackgroundThe current financial and time commitment for a pharmaceutical company to bring a drug to market is approximately $2 billion and 10 years, respectively. A significant portion of that cost is due to...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomedical, Drug discovery, Obstetric/Gynecological, Research tool, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Non-Invasive Assay for Confirming Fertilization and Predicting Developmental Potential Of Embryo
NU 2010-048 InventorsAlison KinThomas O'Halloran*Teresa Woodruff*Miranda Lee BernhardtBetty KongEmily QueShort Description A simple assay to predict oocyte fertilization and embryo quality.AbstractNorthwestern researchers have developed a non-invasive, colorimetric assay for predicting embryo quality and oocyte fertilization. The assay relies on the...
Published: 11/15/2024   |   Inventor(s):  
Keywords(s): Biomarker, Diagnostics, Obstetric/Gynecological, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Bioscaffolds for Replacement Ovaries
NU 2014-044 and NU 2014-045 Inventors Teresa Woodruff* Adam Jakus Jason Wertheim Monica Laronda Ramille Shah Short Description Novel technique for removing cells from ovarian tissue to obtain the extracellular matrix scaffolds for organ engineering applications Abstract Researchers from Northwestern University have developed a...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Biomedical, Devices, Health IT, Manufacturing/Processing, Materials, Medical device, Obstetric/Gynecological, Research tool, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Ex Vivo Female Reproductive System
NU 2013-009 InventorsTheresa K. Woodruff* Takeshi Kurita Ji-Yong Julie Kim Joanna Burdette Jie Zhu Yuanming Xu Yanni Yu Yu Liu Sevim Yildiz Arslan Short DescriptionAdvanced three dimensional model of the female reproductive tract that approximates the human hormonal response for pharmaceutical and toxicology testing AbstractProf. Theresa Woodruff's...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Biomedical, Devices, Drug discovery, Education, Instrumentation, Obstetric/Gynecological, Research tool, Simulation, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Modulation of Oocyte Meiotic Progression through Manipulation of Zinc Availability
NU 2011-100InventorsAlison KimThomas O'HalloranTeresa Woodruff*Miranda Lee BernhardtBetty KongAbstractNorthwestern researchers have discovered and developed a novel way to improve the outcome of assisted reproductive technology (ART). They found that zinc plays a critical and previously unrecognized role in the control of meiotic progression in the...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Obstetric/Gynecological, Therapeutics
Category(s): Life Sciences > Therapeutics
Sealants for Fetal Membrane Repair
NU 2009-127 Inventors Carrie Brubaker Phillip B. Messersmith* Andreas Zisch Short Description Tissue glue for prevention and treatment of fetal membrane rupture Abstract Invasive diagnostic and therapeutic interventions in utero frequently are complicated by amniotic fluid leakage, separation of amnion and chorion, or even iatrogenic preterm premature...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Adhesive, Biomedical, Devices, Health IT, Materials, Medical device, Obstetric/Gynecological, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
An Animal Model for Uterine Fibroid Embolization
NU 2006-021 InventorsReed Omary Robert Ryu AbstractNorthwestern investigators have created an animal model platform that successfully induces the formation of fibroids in the rabbit uterus. They are able to use MRI to detect acute perfusion changes in this model following uterine artery embolization (UAE). Such an animal model would be desirable for...
Published: 4/4/2025   |   Inventor(s):  
Keywords(s): Animal Model, Obstetric/Gynecological, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools