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A Novel Thermal Method to Inactivate Rotavirus for Use in Vaccines
Rotavirus is a highly contagious, diarrhea-inducing pathogen that annually causes approximately 250,000 deaths worldwide and millions of hospitalizations, especially afflicting infants and young children. One strategy to combat this virus is through vaccination. Continuing safety and efficacy concerns with the currently existing live, oral vaccines...
Published: 10/28/2024   |   Inventor(s): Roger Glass, Jean-Francois Saluzzo, Baoming Jiang
Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DXXXXX, Inactivation, Listed LPM Surabian as of 4/15/2015, NCIRD, OID-NCIRD-DVD, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, rotavirus, thermal
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Therapeutics
Human Rotavirus Strains and Vaccines for Neonatal Childhood Protection
This invention relates to rotavirus vaccine compositions and methods of vaccination. Rotaviral infection is the most commonly occurring gastrointestinal illness of children world, affecting both developed and developing economies. Additionally, rotavirus infections can affect livestock (especially calves and piglets), and resulting mortality/morbidity...
Published: 10/28/2024   |   Inventor(s): Roger Glass, Yuhuan Wang, Jon Gentsch, Baoming Jiang
Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, CHILDHOOD, Children, DB4BXX, DB4XXX, DBXXXX, DC5BXX, DC5XXX, DCXXXX, DEVELOPED, DEVELOPING, DIARRHEA, DXXXXX, Dysentery, GASTRIC, gastrointestinal, Human, Livestock, NEONATAL, Neonates, OID-NCIRD-DVD, rotavirus, Strain, STRAINS, Vaccine, VETERINARY, VETERINARY vaccine, viral, virus, VLXXXX, VOXXXX, WIXXXX, WJXXXX, WMXXXX, XEXXXX, XHXXXX, YBXXXX, YCXXXX, Zoo, Zoonotic
Category(s): Collaboration Sought > Licensing, Application > Research Materials, ResearchProducts > Research Equipment, Application > Vaccines, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease