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Search Results - nasir+malik
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Astrocyte Differentiation of Neural Stem Cells with StemPro Embryonic Stem Cell Serum Free Medium for Research and Potential Therapeutic Use
This technology includes an innovative method for differentiating astrocytes from neural stem cells (NSCs). The process involves using Life Technologies StemPro embryonic stem cell serum-free medium to initially guide NSCs towards a neuronal lineage. Over a period of 28-35 days, as the cells are continually passaged, neurons gradually die off, leading...
Published: 9/10/2024
|
Inventor(s):
Nasir Malik
,
Mahendra Rao
,
Xianmin Zeng
Keywords(s):
Category(s):
Application > Research Materials
,
Collaboration Sought > Materials Available
,
ResearchProducts > Human Cell Lines
,
TherapeuticArea > Neurology
Conditional Cell Immortalization Plasmid for Basic Science Research
This technology includes a novel plasmid design for cell immortalization. It uniquely combines the conditional activation of human telomerase and c-myc genes through cumate addition, a method distinct from traditional immortalization techniques which commonly use SV40 T-antigen, telomerase, or c-myc. This plasmid also includes a GFP reporter and a puromycin...
Published: 8/12/2024
|
Inventor(s):
Nasir Malik
Keywords(s):
Category(s):
Application > Research Materials
,
Collaboration Sought > Materials Available
,
ResearchProducts > Plasmids/Vectors
Neural Stem Cells from an iPSC Line Ubiquitously Expressing Green Fluorescent Protein for Basic Science Research and Cell Line Tracking
This technology involves neural stem cells (NSCs) derived from pluripotent stem cells (PSCs) that can differentiate into neurons and glia. The key feature of this technology is the CY2 EEF1A1 GFP iPSC line, which includes a green fluorescent protein (GFP) expressed under the EEF1A1 promoter, leading to its ubiquitous expression in cells. This characteristic...
Published: 9/10/2024
|
Inventor(s):
Nasir Malik
,
Mahendra Rao
Keywords(s):
Category(s):
Application > Research Materials
,
Collaboration Sought > Materials Available
,
ResearchProducts > Human Cell Lines
,
TherapeuticArea > Neurology
A Neural Stem Line from a Niemann Pick C (NPC) Type 1 Patient for Therapy Development
This technology includes a neural stem cell (NSC) line derived from a Niemann Pick C (NPC) patient, aimed at advancing research and drug development for NPC, an inherited neurodegenerative disorder characterized by the accumulation of cholesterol in neurons. The NSCs, which serve as a crucial intermediate cell type, can be differentiated into any neuronal...
Published: 8/12/2024
|
Inventor(s):
Nasir Malik
Keywords(s):
Category(s):
Application > Research Materials
,
Collaboration Sought > Materials Available
,
ResearchProducts > Human Cell Lines
,
TherapeuticArea > Metabolic Disease
,
TherapeuticArea > Neurology
Neuronal Differentiation of Neural Stem Cells with StemPro Embryonic Stem Cell Serum Free Medium for Research and Therapeutic Development
This technology involves an innovative method for differentiating neural stem cells (NSCs) into neurons, primarily for use in basic science research and in developing therapies for brain and spinal cord disorders. Existing methods for generating neurons from NSCs typically result in high efficiency but low survival rates, especially when neurons are...
Published: 8/12/2024
|
Inventor(s):
Nasir Malik
,
Mahendra Rao
Keywords(s):
Category(s):
Application > Research Materials
,
Collaboration Sought > Licensing
,
ResearchProducts > Human iPSC Lines
,
TherapeuticArea > Neurology
Engineering Neural Stem Cells Using Homologous Recombination
Methods for modifying the genome of a Neural Stem Cell (NSC) are disclosed. Also, methods for differentiating NSCs into neurons and glia are described. NSCs are multipotent, self-renewing cells found in the central nervous system, capable of differentiating into neurons and glia. NSCs can be generated efficiently from pluripotent stem cells (PSCs)...
Published: 7/30/2024
|
Inventor(s):
Mahendra Rao
,
Jizhong Zou
,
Raymond Funahashi
,
Nasir Malik
Keywords(s):
Cells
,
EFFECTOR
,
Gene
,
Listed LPM Vepa as of 4/15/2015
,
NB1XXX
,
Nucleases
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
SOMATIC
,
TAl
,
Targeting
,
VEXXXX
,
WIXXXX
,
WJXXXX
,
XEXXXX
,
YAXXXX
,
YBXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Research Materials
,
Application > Therapeutics
,
TherapeuticArea > Neurology
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Twistron Mechanical Energy Harvesters
Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, automotive technologies, and the extraction of energy from ocean waves. Until now, few harvesters have been flexible enough to be used as yarns in textiles, and the performance of such yarns has been...
Published: 6/26/2024
|
Inventor(s):
Shi Hyeong Kim
,
Carter Haines
,
Na Li
,
Keon Jung Kim
,
Tae Jin Mun
,
Changsoon Choi
,
Jiangtao Di
,
Shaoli Fang
,
Seon Jeong Kim
,
Ray Baughman
Keywords(s):
Automotive
,
Carbon Nanomaterials
,
Carbon Nanotubes
,
Electronics
,
Energy, Cleantech & Environmental
,
Engineering & Physical Sciences
,
Renewable Energy
,
Sensors & Controls
,
Textiles
,
Wireless
Category(s):
Nanotechnology
Intelligent Textiles Prepared from Nanofiber Yarns and Polymer Fiber Actuators
While there has always been a desire for smart textiles, including fabrics which adapt depending on environmental stimuli, it has yet to be effectively accomplished due to the lack of suitable materials. These polymer fiber actuators have enabled the creation of fabrics that can reversibly change properties such as porosity, shape, color and texture....
Published: 4/22/2021
|
Inventor(s):
Ray Baughman
,
Ozer Goktepe
,
Fatma Goktepe
,
Na Li
,
Marcio Lima
,
Carter Haines
,
Shaoli Fang
Keywords(s):
Engineering & Physical Sciences
,
Industrial & Manufacturing
,
Nanotechnology
,
Polymers
,
Textiles
Category(s):
Materials
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
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