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Engineering Neural Stem Cells Using Homologous Recombination
Methods for modifying the genome of a Neural Stem Cell (NSC) are disclosed. Also, methods for differentiating NSCs into neurons and glia are described. NSCs are multipotent, self-renewing cells found in the central nervous system, capable of differentiating into neurons and glia. NSCs can be generated efficiently from pluripotent stem cells (PSCs)...
Published: 10/28/2024   |   Inventor(s): Mahendra Rao, Jizhong Zou, Raymond Funahashi, Nasir Malik
Keywords(s): Cells, EFFECTOR, Gene, Listed LPM Vepa as of 4/15/2015, NB1XXX, Nucleases, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, SOMATIC, TAl, Targeting, VEXXXX, WIXXXX, WJXXXX, XEXXXX, YAXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Neurology