Search Results - christhian+ildefonso

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Adeno-Associated Virus-Based Serpin Delivery for Use as Anti-Inflammatory Gene Therapy
Recombinant Adeno-Associated Virus (rAAV) Vector Expressing Serine Proteinase Inhibitor 1 for Inhibiting Multiple Targets in the Inflammatory Cascade This recombinant AAV vector encoding a serine proteinase inhibitor (Serp-1) downregulates inflammation by targeting and inhibiting human serine proteinase enzymes. Inflammatory disorders, including lupus,...
Published: 1/20/2026   |   Inventor(s): Alfred Lewin, Alexandra Lucas, Westley Reeves, Douglas McFadden, Christhian Ildefonso, Sriram Ambadapadi
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Therapeutics
AAV Vector that Promotes Antioxidant Production for Treatment of Age-Related Macular Degeneration
Gene Therapy Requires Just One Intraocular Injection to Treat Eye Ailment Caused by Oxidative StressThis AAV gene therapy approach provides a one-time treatment to oxidative stress. Sustained oxidative stress can lead to a variety of pathophysiological diseases including age-related macular degeneration, diabetic retinopathy, and amyotrophic lateral...
Published: 1/20/2026   |   Inventor(s): Qiuhong Li, Christhian Ildefonso, Alfred Lewin
Keywords(s): Age Related Macular Degeneration, Alzheimer's Disease, Diabetic Retinopathy, Gene Therapy, Macular Degeneration, Retinal Degeneration, uveitis
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Others