Search Results - eran+halperin

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Engineered sugar uptake in yeast cells
The technology focuses on engineered transporter proteins that enhance the uptake of specific monosaccharides like xylose and arabinose into yeast cells, improving their efficiency and selectivity for biofuel and biochemical production. Background The efficient conversion of lignocellulosic biomass into biofuels and bio­chemicals is a critical...
Published: 8/15/2024   |   Inventor(s): Hal Alper, Eric Young
Keywords(s):  
Category(s): Life sciences > Metabolic engineering, Life sciences > Research tools, Physical sciences > Energy > Renewable
Automated Biomarker Prediction Using Optical Coherence Tomography (Case No. 2020-467)
Summary: UCLA researchers in the Department of Computational Medicine have developed a computer program capable of automatically and accurately diagnosing optical diseases using OCT. Background: Optical diseases, such as age-related macular degeneration (AMD), are serious issues that, if left untreated, can result in partial and even complete blindness....
Published: 7/22/2024   |   Inventor(s): Eran Halperin, Nadav Rakocz, Jeffrey Chiang, Muneeswar Gupta, Srinivas Sadda
Keywords(s): Image Processing, Medical Imaging, Software & Algorithms
Category(s): Medical Devices > Medical Imaging, Software & Algorithms > Image Processing
Metabolic engineering of Yarrowia lipolytica for high‑level polyketide production
Background The field of biotechnology has seen significant advancements in the use of genetically modified organisms to produce valuable compounds. Polyketides, a diverse class of secondary metabolites, are of particular interest due to their wide-ranging applications in pharmaceuticals, bioactive compounds, and renewable chemicals. Traditional methods...
Published: 7/11/2024   |   Inventor(s): Hal Alper, Kelly Markham, Claire Palmer
Keywords(s):  
Category(s): Life sciences > Metabolic engineering, Life sciences > Biomaterials, Life sciences > Therapeutics > Synthetic biology
Revolutionizing plastic recycling: FAST-PETase enzyme variant
Background Plastic waste is a pressing ecological challenge, with a staggering 8.3 billion metric tons produced, of which 6 billion tons become waste. Traditional methods of plastic degradation, such as chemical processes, are costly and generate harmful byproducts. Enzymatic degradation presents a sustainable alternative, with poly (ethylene terephthalate)...
Published: 3/4/2024   |   Inventor(s): Hal Alper, Andrew Ellington, Daniel Diaz, Hongyuan Lu
Keywords(s):  
Category(s): Life sciences > Agriculture, Life sciences > Metabolic engineering
Plastic-degrading enzymes
Able to break down PET plastics in as little as 24 hours Overview Plastic waste poses an ecological challenge. There have been 8.3 billion metric tons of plastics produced—6 billion tons are waste. What do we do with this waste? The long-term, sustainable solution is to find effective ways to break down the plastic into smaller parts and then...
Published: 2/28/2024   |   Inventor(s): Hal Alper, Andrew Ellington, Hongyuan Lu
Keywords(s):  
Category(s): Physical sciences > Green tech, Life sciences > Agriculture, Life sciences > Research tools > Reagent
A Process for Identifying Health Modifying Interventions Through Epigenetic Prediction (Case No. 2023-107)
Summary: UCLA researchers in the Department of Neurology have developed a novel method that leverages epigenetic markers to identify recommended and necessary health interventions. Background: Disease risk prediction and intervention involves identifying individuals or populations with a higher likelihood of developing a particular condition based...
Published: 3/22/2024   |   Inventor(s): Noah Zaitlen, Eran Halperin, Elior Rahmani, Michael Thompson, Zeyuan (Johnson) Chen
Keywords(s): Clinical decision support system, clinical outcome, Clinical Trial, disease outcome, Epigenetics, health risk assessment, outcome probability, patient outcome, prognostic, Public Health, public health monitoring, Risk Assessment, risk reduction, risk score, Simulation & Modeling, statistical modeling, treatment efficacy
Category(s): Software & Algorithms, Software & Algorithms > Data Analytics, Software & Algorithms > Digital Health, Software & Algorithms > Statistical Models, Medical Devices, Medical Devices > Monitoring And Recording Systems
A Uniform AI Framework for Automated Detection of Disease-Related Risk Factors in 3D Medical Imaging Data
Summary: UCLA researchers from the Departments of Anesthesiology & Perioperative Medicine, Ophthalmology, Computational Medicine, and Computer Science have developed a novel uniform framework to diagnose disease-related risk factors in any volumetric medical imaging data. Background: Automated diagnosis of medical imaging is undoubtedly important...
Published: 7/19/2023   |   Inventor(s): Oren Avram, Eran Halperin, Berkin Durmus, Nadav Rakocz, Jeffrey Chiang, Srinivas Sadda
Keywords(s): Advanced Computing / AI, AI algorithms, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, Biomarker, Biomedical Engineering, Computer-Aided Design, Deep Learning, Imaging, Magnetic Resonance Imaging, Medical Imaging
Category(s): Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices > Medical Imaging
BioPod: A platform for increasing efficiency and reducing costs of biomanufacturing
Problem statement Biology can be harnessed to produce a large share of the global economy’s physical materials, potentially with improved performance and sustainability. Fermentation, for centuries used to brew beer and make bread, is now being used to create high-value ingredients such as collagen and spider silk. According to McKinsey, biologically...
Published: 11/1/2023   |   Inventor(s): Hal Alper, Shuo-Fu Yuan, James Wagner, Trevor Johnston, Alshakim Nelson
Keywords(s): 3D printing, Biologics, Industrial manufacturing, Manufacturing, Pharmaceuticals, Synthesis methods
Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics > Manufacturing platform
2022-113 AI MODELS FOR OCULAR DISEASES USING OPTICAL COHERENCE TOMOGRAPHY
Summary: UCLA researchers in the Department of Computational Medicine have developed a computer program capable of automatically and accurately diagnosing optical diseases using OCT. Background: Optical diseases, such as age-related macular degeneration, are serious issues that, if left untreated, can result in partial and even complete blindness....
Published: 7/22/2024   |   Inventor(s): Jeffrey Chiang, Srinivas Sadda, Eran Halperin
Keywords(s): Algorithm Optical Coherence Tomography, Artificial Intelligence, Eye Surgery, Intraocular Lens , Lens (Optics), Macular Degeneration, Optical Coherence , Optical Microscope, Optical Tomography
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices > Medical Imaging
2020-862 Early Prediction of Mechanical Ventilation Need in COVID-19 Patients Using Clinician-Constrained Decision Trees
SUMMARYUCLA researchers in the Department of Computer Science have developed a tree model with machine learning to determine the need for mechanical ventilators, which is important during a shortage of mechanical ventilators in a hospital.BACKGROUNDMechanical ventilation is used to help a patient breath when they find it difficult to breathe on their...
Published: 7/19/2023   |   Inventor(s): Elior Rahmani, Brian Hill, Zeyuan (Johnson) Chen, Eran Halperin, Vladimir Manuel
Keywords(s):  
Category(s): Software & Algorithms > Programs
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