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Search Results - liwen+zhou
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Specialized storage technology for preserving axonal viability
A specialized calcium-free solution preserves peripheral nerve axons for up to nine days at low temperatures, enhancing nerve graft viability for effective repair of injuries using polyethylene glycol fusion, promoting rapid sensory and motor recovery. Background Peripheral nerve injuries (PNIs) often result in segmental-loss defects, leading to immediate...
Published: 10/21/2024
|
Inventor(s):
George Bittner
,
David Jackson
,
Alexa Olivarez
,
Liwen Zhou
,
Cathy Yang
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 9/13/2024
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Inventor(s):
Wen Li
,
Hasan Banna
,
James Siegenthaler
Keywords(s):
Category(s):
Agriculture
,
Analytical Instruments
,
Environment
,
Test and Measurement
MEDREX (Case No. 2024-244)
Summary: UCLA researchers have developed a new software package to reconcile medication lists between different electronic health records. Background: Reconciliation is a crucial process that ensures patients’ medication lists are accurate. This process is especially important for patients with memory impairments, who may be more vulnerable...
Published: 10/18/2024
|
Inventor(s):
Li Zhou
,
Richard Korf
,
Cindy Liu
,
Edmond Wen
,
Advaith Gowrishetty
,
Jonathan Xu
,
Nicole Ju
Keywords(s):
Software
,
Software & Algorithms
,
Software Development Tools
,
Software-enabled learning
Category(s):
Software & Algorithms
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > Digital Health
,
Software & Algorithms > Programs
,
Software & Algorithms > Data Analytics
Activation of E6Ap/Ube3A-Mediated Protein Ubiquitination and Degradation Pathways By A Cyclic G-Aa Peptide
Advantages By modulating E3 ligase activity, it is possible to regulate protein degradation pathways, gene activation, and other cellular functions. The research expands the therapeutic landscape by introducing the concept of E3 activators alongside E3 inhibitors, PROTACs, and molecular glues. Synthetic ligands, such as γ-AA peptides, offer...
Published: 4/18/2024
|
Inventor(s):
Jianfeng Cai
,
Bo Huang
,
Jun Yin
,
Li Zhou
,
Ruochuan Liu
Keywords(s):
Cancer Treatment
,
Drug Discovery
,
Neurodegenerative Diseases
,
Oncology
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical > Neuroscience
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Implantable Neural Microelectrodes and Fabrication Method
Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...
Published: 2/17/2023
|
Inventor(s):
Wen Li
,
Yue Guo
,
Thomas Schuelke
,
Michael Becker
,
Robert Rechenberg
,
Cory Rusinek
Keywords(s):
Category(s):
Advanced Materials
,
Biotechnology
,
Devices
Flexible Hybrid Diamond Biosensor
Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...
Published: 6/8/2021
|
Inventor(s):
Wen Li
,
Bin Fan
,
Michael Becker
,
Robert Rechenberg
Keywords(s):
Category(s):
Advanced Materials
,
Devices
Wireless Intraocular Pressure Sensor to Monitor Glaucoma Patients
Executive SummaryGlaucoma is a leading cause of blindness that affects up to 3 million people in American. It can remain undetected until permanent vision loss is present. Measuring eye pressure during an office visit is a standard diagnostic tool. However, this measurement can only report on pressure during a brief time sample. Patients with variable...
Published: 6/15/2023
|
Inventor(s):
Wen Li
,
Arthur Weber
,
Mohammad Hossein Kouhani
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Test and Measurement
Transparent Electrode Array for Optogenetics
Executive SummaryThe development of brain-machine interface technologies offer a host of opportunities for basic research, real-time therapeutic devices, and neural prosthetics. Our bi-directional communication channel provides for a more robust brain-machine interface with greater accuracy. The bi-directional communication channel is also critical...
Published: 6/15/2023
|
Inventor(s):
Wen Li
,
Ki Yong Kwon
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Devices
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
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