Search Results - liwen+zhou

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025   |   Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar
Keywords(s):  
Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025   |   Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Specialized storage technology for preserving axonal viability
A specialized calcium-free solution preserves peripheral nerve axons for up to nine days at low temperatures, enhancing nerve graft viability for effective repair of injuries using polyethylene glycol fusion, promoting rapid sensory and motor recovery. Background Peripheral nerve injuries (PNIs) often result in segmental-loss defects, leading to immediate...
Published: 1/13/2026   |   Inventor(s): George Bittner, David Jackson, Alexa Olivarez, Liwen Zhou, Cathy Yang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Formulation
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025   |   Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason
Keywords(s):  
Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement
MEDREX (Case No. 2024-244)
Summary: UCLA researchers have developed a new software package to reconcile medication lists between different electronic health records. Background: Reconciliation is a crucial process that ensures patients’ medication lists are accurate. Transitioning between facilities using different electronic health record (EHR) systems can exacerbate...
Published: 6/2/2025   |   Inventor(s): Li Zhou, Richard Korf, Cindy Liu, Edmond Wen, Advaith Gowrishetty, Jonathan Xu, Nicole Ju
Keywords(s): Software, Software & Algorithms, Software Development Tools, Software-enabled learning
Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Programs, Software & Algorithms > Data Analytics
Activation of E6Ap/Ube3A-Mediated Protein Ubiquitination and Degradation Pathways By A Cyclic G-Aa Peptide
Advantages By modulating E3 ligase activity, it is possible to regulate protein degradation pathways, gene activation, and other cellular functions. The research expands the therapeutic landscape by introducing the concept of E3 activators alongside E3 inhibitors, PROTACs, and molecular glues. Synthetic ligands, such as γ-AA peptides, offer...
Published: 4/18/2024   |   Inventor(s): Jianfeng Cai, Bo Huang, Jun Yin, Li Zhou, Ruochuan Liu
Keywords(s): Cancer Treatment, Drug Discovery, Neurodegenerative Diseases, Oncology
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications > Medical > Neuroscience
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Implantable Neural Microelectrodes and Fabrication Method
Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...
Published: 2/17/2023   |   Inventor(s): Wen Li, Yue Guo, Thomas Schuelke, Michael Becker, Robert Rechenberg, Cory Rusinek
Keywords(s):  
Category(s): Advanced Materials, Biotechnology, Devices
Flexible Hybrid Diamond Biosensor
Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...
Published: 6/8/2021   |   Inventor(s): Wen Li, Bin Fan, Michael Becker, Robert Rechenberg
Keywords(s):  
Category(s): Advanced Materials, Devices
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