Search Results - lindsay+guzman

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Electrically Gated Solid-State Molecular Thermal Transistor (Case No. 2024-099)

Summary: UCLA researchers have introduced a solid-state thermal transistor that achieves groundbreaking performance and facilitates improved heat flow manipulation. Background: The forefront of thermal management is marked by the exploration of molecular thermal transistors, driven by the quest for more efficient electronic devices. Researchers are...

Published: 7/16/2024 | Inventor(s): Yongjie Hu, Paul Weiss, Man Li

Keywords(s): ; self-assembled molecule, Composite Material, Doping (Semiconductor), Elastic Modulus Thermal Grease, Electronics & Semiconductors, field-effect transistors (FETs), Functional Materials, heat control, heat controlling devices, infrared thermal imaging, Microelectronics Semiconductor Device Fabrication, molecular design, molecular engineering, molecular junction, Nanomaterials, Optoelectronic materials, Optomechanical Thermal Imaging Transducer, organic field effect transistors, Organic Semiconductor, phase change materials, Rechargeable Battery Thermal Conductivity, self-assembled molecule, Semiconductor, semiconductor chip foundries, Semiconductor Device, Semiconductor Device Fabrication, Semiconductor Ohmic Contact, Semiconductor Risk Assessment, Semiconductor Sapphire, Semiconductors, solid-state thermal transistor, strength-thermal stability, switching reversibility, thermal circuit, thermal compression bonding, thermal conductance, Thermal Energy Storage, thermal fusion, thermal imaging, thermal management systems, thermal stability, thermal switching speed, thermal switching speeds, thermal transistor, Thin-Film Transistor, Transistor, transistors, zzsemiconducting materials

Category(s): Electrical, Electrical > Electronics & Semiconductors, Energy & Environment, Energy & Environment > Energy Generation, Energy & Environment > Energy Storage, Energy & Environment > Energy Transmission, Energy & Environment > Thermal, Electrical > Instrumentation, Materials, Materials > Nanotechnology

Self-neutralizing air-breathing thruster and method of neutralization

An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Anmol Taploo, Li Lin

Keywords(s):

Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing

Intracellular Delivery of Small Molecule Reactive Ligands for Bioconjugation

A protected small molecule probe is delivered intracellularly and subsequently releases an aryl diazonium ion for use as a bioconjugation agent or drug delivery agent. This technology enables a novel chemical probe for observing intact biological cells. It builds on previous IP developed by Jewett laboratory for protection, as a class of chemistry enabling...

Published: 9/5/2024 | Inventor(s): John Jewett, Natasha Cornejo, Bismark Amofah, Lindsay Guzman, W Mudiyanselage Anjalee Wijetunge, Indraneel Ghosh, Danielle Johnson, Abigail Shepard

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Category(s): Technology Classifications > Materials > Chemicals, Technology Classifications > Research Tools > Reagents

Amphiphilic macromolecules with novel hydrophobic segments

Invention Summary: Cardiovascular diseases are the leading cause of mortality in developed countries. Atherosclerosis, defined as the buildup of lipid rich plaques within the vascular intima, is the foremost pathology underlying these conditions. This causes irregular uptake of oxidized low-density lipoproteins (OxLDL) which leads...

Published: 4/17/2024 | Inventor(s): Kathryn Uhrich, Allison Faig, Dalia Abdelhamid, Li Gu

Keywords(s): Antibacterial, Biomaterials, Polymers & Composites

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

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Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 7/30/2024 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

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Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

Triazabutadienes as Cleavable Protein Linkers

This technology describes water-soluble triazabutadienes as cleavable cross linkers. Upon changes in chemical conditions, triazabutadienes release a highly reactive diazonium species, enabling delivery of the cross-linked molecule. Background: Cross linking is becoming a valuable practice in chemistry, including for life science applications, with...

Published: 6/20/2024 | Inventor(s): John Jewett, Lindsay Guzman, Flora Kimani, Brandon Cornali

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Category(s): Technology Classifications > Materials > Polymers

Enzymatically Released Aryl Diazonium Ions

This invention is the discovery of triazebutadienes that rapidly release aryl diazonium ions at neutral pH with a half-life of approximately one minute. Background: In 2015, the global protein therapeutics market grew to nearly $174.7 billion due to trends in targeted therapies that resulted in fewer side effects. Monoclonal antibodies and biologics...

Published: 6/20/2024 | Inventor(s): John Jewett, Lindsay Guzman, Bereketab Mehari, Jie He

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Category(s): Technology Classifications > Life Sciences

Releasable Triazabutadienes

This invention is a chemical means of protecting triazylbutadienes from degradation in acidic conditions. When exposed to a predetermined specific enzyme, the system can release triazylbutadiene. Triazylbutadienes can then go on to release aryl diazonium. This aryl species can be apart of various coupling reactions. This invention has the potential...

Published: 3/12/2024 | Inventor(s): John Jewett, Lindsay Guzman, Flora Kimani

Keywords(s):

Category(s): Technology Classifications > Sensors & Controls, Technology Classifications > Sensors & Controls > Chemical & Gas, Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Materials > Chemicals, Technology Classifications > Materials > Biomaterials, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic

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