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Novel treatment for pseudomyxoma peritonei
Reference #: 1692 The University of South Carolina is offering licensing opportunities for Novel treatment for pseudomyxoma peritonei. Background: Pseudomyxoma peritonei (PMP) is a rare cancer, which originates as an appendiceal neoplasm. Due to its usually poor vascularization and floating as nodules, PMP spreads easily to the peritoneal cavity,...
Published: 6/11/2024   |   Inventor(s): Jie Li, Daping Fan, Hexin Chen, Traci Testerman
Keywords(s):  
Category(s): Biomedical and Life Sciences, Health Sciences
Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application
Reference #: 1678 The University of South Carolina is offering licensing opportunities for Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application. Background: The gut microbiota plays a key role in health and disease. The balance between beneficial genera (such as Alistipes and Odoribacter) and harmful species (such...
Published: 8/13/2024   |   Inventor(s): Jie Li, Hexin Chen, Daping Fan
Keywords(s):  
Category(s): Biomedical and Life Sciences, Health Sciences
Improved resuscitation in hemorrhagic shock using polyethelyne glycol modified albumin (PEG-Alb).
Background Capillary leakage of important ions and proteins, such as albumin from blood vessels can lead to a buildup of fluid in interstitial space (organ swelling) as well as hypoperfusion of organs. Capillary leak (CL) is a central component of multiorgan failure and a secondary component to severe sepsis caused by bacterial or viral infections,...
Published: 5/9/2024   |   Inventor(s): Ragheb Assaly, J Dignam, Joseph Shapiro
Keywords(s):  
Category(s): Inflammation & Immunity
Artificial Intelligence-Assisted Projection-Resolved Optical Coherence Tomographic Angiography (aiPR-OCTA)
Summary The current artificial intelligence algorithm removes projection artifacts in optical coherence tomographic angiography images and improves the signal-to-noise ratio. Technology Overview A major limitation of optical coherence tomography angiography (OCTA) are image artifacts, particularly projection artifacts, which make the detection of...
Published: 1/7/2025   |   Inventor(s): Yali Jia, Jie Wang
Keywords(s): Imaging, Imaging - Other
Category(s): Imaging
New Carbon Dioxide Absorbent Material
THE CHALLENGE Concerns of global warming have been growing over the last decade. One of the driving forces of these concerns is the amount of carbon dioxide in the atmosphere. It allows more heat into the atmosphere than most other particles while also remaining in the atmosphere for a very long time. Due to this, methods for absorbing and utilizing...
Published: 6/11/2024   |   Inventor(s): Amanda Morris, Jie Zhu
Keywords(s):  
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications, Technology Classifications > Environment/Green Tech
Antimicrobial Antibody Panels for Lung Cancer Detection
the second most common cancer in both men and women and the leading cause of cancer death in the US. Although there are risk factors for lung cancer, such as smoking, there are many cases where the patient never smoked. Because of this, there is growing interest in investigating the lung microbiota and how that may promote or prevent disease. Yearly...
Published: 8/2/2023   |   Inventor(s): Mahasish Shome, Ji Qiu, Yunro Chung, Joshua LaBaer
Keywords(s):  
Category(s): Cancer, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Assistive Device to Aid in Identification and Use of Medications (UCLA Case No. 2022-213)
Summary: Researchers in the UCLA Stein Eye Institute have developed a medication assistive device to aid in distinguishing medication bottles and administering medications on the correct schedules for patients, especially those with visual impairment. Background: Many ophthalmic conditions are treated with eye drop medications. These treatments...
Published: 11/15/2024   |   Inventor(s): Edmund Tsui, Jie Deng, Holly Huang, Jeffrey Li, Hyeongtaek Nam, Brian Wu
Keywords(s): 3D Printing, Hospital Systems And Devices, Medical Devices and Materials, Monitoring And Recording Systems, Ophthalmology, Therapeutics & Vaccines
Category(s): Medical Devices > Monitoring And Recording Systems, Therapeutics > Ophthalmology
Autoantibodies for Identification of False Positives of Disease and Uses Thereof
Autoantibodies are an excellent biomarker for both autoimmune disease and cancer, however, some autoantibodies, called common autoantibodies, have been found to occur frequently in healthy individuals. The presence of these common autoantibodies can impede the search for disease-linked autoantibodies or lead to false positives. The identification of...
Published: 3/30/2023   |   Inventor(s): Mahasish Shome, Yunro Chung, Ramani Chavan, Jin Park, Ji Qiu, Joshua LaBaer
Keywords(s):  
Category(s): Applied Technologies, Cancer, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Novel Antibodies for Detecting Gastric Cancer or Gastric Intestinal Metaplasia
Gastric cancer (GC) is a major public health problem in many countries, with more than 1 million new cases, worldwide, in 2020, contributing to almost 800,000 deaths. And new research suggests that GC may be on the rise in the US, particularly among younger adults. Early detection of GC often allows for greater therapeutic options, however, because...
Published: 3/7/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Lusheng Song, Yunro Chung
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools
Type 1 Diabetes Biomarkers
Type 1 Diabetes (T1D) is one of the most common juvenile autoimmune diseases and is characterized by progressive destruction of pancreatic ß-cells. By the time of T1D diagnosis, around 70-90% of pancreatic ß-cells are already dead. T1D patients face many potential health complications and co-morbidities which lead to both personal and societal...
Published: 2/23/2023   |   Inventor(s): Joshua LaBaer, Ji Qiu, Xiaofang Bian, Desmond Schatz, Clive Wasserfall, Mark Atkinson
Keywords(s): Autoantibody, Bioanalysis, biomarker, Detection, Diabetes, Diagnostics, Early Detection, ELISA, Screening
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
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