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Assembly of Vaccines Using Cell-Free Integration of Viral Membrane Proteins into Liposomes
SHORT DESCRIPTION A cell-free method that assembles vaccines by integrating viral membrane proteins into liposomes, enabling rapid prototype production without cold chain requirements. INVENTORS Neha Kamat* McCormick School of Engineering, Department of Biomedical Engineering Hector Aguilar-Carreno Susan...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): Immunology, Infectious disease, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Micro-Ovary: A Self-Assembled Ovary at Microscale Resolution
fidelity drug screening and reproductive applications. INVENTORS Francesca Duncan* Aubrey Converse Lauren Haky * Principal Investigator NU Tech ID: NU 2025-292 IP STATUS Pending DEVELOPMENT STAGE TRL-4 Prototype Validated in Lab: Self-assembly and follicle encapsulation have been demonstrated...
Published: 6/2/2026   |   Updated: 6/2/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics
Ultrasensitive and High-Throughput Single Cell RNA Sequencing Technology
NU 2024-199 INVENTORS Yogesh Goyal* Emanuelle Grody Elena Martinelli SHORT DESCRIPTION Single-cell Amplified Libraries for Variant isoform Enrichment sequencing (SALVEseq), is an innovative experimental and computational workflow designed to detect rare RNA isoforms, such as viral RNA, in single cells. BACKGROUND Standard single-cell RNA...
Published: 5/27/2026   |   Updated: 5/21/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
A Biosensor Engineering Strategy for Improved Cell-based Therapy
NU 2016-174 Inventors Joshua N. Leonard* Kelly A. Schwarz Rachel M. Dudek Short Description A sophisticated multiplexed biosensor system that can activate a downstream promoter to effect diverse custom biological functions. #therapeutics #cellsignaling #healthcare #diagnostictool Background The market for cell-based therapeutics has gained wide...
Published: 5/12/2026   |   Updated: 5/12/2026   |   Inventor(s):  
Keywords(s): Biotechnology, Cell therapy, Research tool, Sensors, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Northwestern Startup: Syenex, Inc.
Northwestern Inventor: Joshua Leonard McCormick School of Engineering Chemical and Biological Engineering Syenex builds bioengineering technologies to unlock the future of human health. Leveraging the power of synthetic biology, we design scalable, precision-engineered components, empowering cell and gene therapy developers to cure disease and build...
Published: 5/5/2026   |   Updated: 5/5/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomedical, Drug delivery, Gene therapy, Platform technology, Research tool, Startup with Northwestern IP, Synthetic biology, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics
Protecting Proprietary Designs via Adversary-Aware Decoy Generation
SHORT DESCRIPTION A computational tool that safeguards proprietary protein designs by generating biochemically plausible decoy proteins to mislead adversaries. INVENTORS V.S. Venkatramanan Subrahmanian, PhD* Walter P. Murphy Professor of Computer Science, Department of Computer Science, McCormick School of Engineering,...
Published: 6/8/2026   |   Updated: 5/1/2026   |   Inventor(s):  
Keywords(s): Artificial Intelligence & Machine Learning, Biotechnology
Category(s): Physical Sciences > Software & Services, Physical Sciences > Engineering & Technology, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT
GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease
NU 2024-175 SHORT DESCRIPTION A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department...
Published: 5/11/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology
Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications
SHORT DESCRIPTION Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry Anna Metlushko Bo...
Published: 5/11/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics
STING Agonist 8803 for Blood-Brain Barrier Opening in Glioblastoma Treatment
SHORT DESCRIPTION Chemical compound that opens the blood-brain barrier to enhance delivery of therapeutics for treating glioblastoma. INVENTORS Amy Heimberger* Northwestern University Feinberg School of Medicine, Department of Neurological Surgery * Principal Investigator NU Tech ID: NU 2025-212 IP...
Published: 5/7/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Adjunct therapy, ALS - Amyotrophic Lateral Sclerosis, Animal Model, Autoimmune disease, Bladder cancer, Brain cancer, Breast cancer, Cancer Treatment, Cancer/Oncology, Cervical cancer, CNS - Central Nervous System, Colon cancer, Drug delivery, Endometrial cancer, Gastric cancer, GBM - Glioblastoma, Head and neck cancer, Immunology, Immunotherapy, Liver cancer, Lung cancer, MS - Multiple Sclerosis, Neurodegenerative disease, Neurologic disease, Ovarian cancer, Pancreatic cancer, PD - Parkinson's Disease, Prostate cancer, Repurposed Drugs, Research tool, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets
SHORT DESCRIPTION A targeted-protein degradation platform for intracellular targets, addressing resistant oncogenic and neurodegenerative targets. INVENTORS Shana Kelley* Weinberg College of Arts & Sciences, Department of Chemistry Yi Li * Principal Investigator NU Tech ID: NU 2025-050 IP...
Published: 5/7/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Biologic, Biomolecular condensates, Cancer/Oncology, Drug delivery, Nanoparticle, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Platform technology, Targeted protein degradation, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
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