Search Results - life+sciences+%3e+biomarkers+%26+biomedical+research+tools

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Location-specific growth media for brain tumor organoids
LU 2023-082 INVENTORS Xiaonan Li* Milagros Suarez Palacios Yuchen Du SHORT DESCRIPTION Location-matched growth media formulations in brain tumor organoid models for biological and therapeutic applications BACKGROUND Brain cancer is the second most common type of childhood malignancy and the leading cause of death in children. Despite recent...
Published: 7/10/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Antibody for Diagnosis of Kawasaki Disease
NU 2018-214 NU 2022-027 INVENTORS Anne Rowley* Stanford Shulman Susan Baker SHORT DESCRIPTION Monoclonal antibodies, produced from Kawasaki disease plasmablasts, whose binding interactions provides a biomarker for disease diagnosis. BACKGROUND Kawasaki disease (KD) manifests as an acute febrile condition in children, exhibiting clinical features...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Novel Biomarker for Lung Disease Diagnosis and Monitoring
NU2022-232 INVENTORS Ankit Bharat* Yuanqing Yan SHORT DESCRIPTION A robust and reliable biomarker for diagnosing and predicting lung disease ABSTRACT The lack of robust biomarkers for lung diseases is a pressing challenge. A team of scientists at Northwestern University has identified the protein serine protease inhibitor Kazal-type 1 (SPINK1)...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Analytical Device for Sorting Single Cells Based on Secreted Products
NU 2023-084 INVENTORS Shana O. Kelley* Zongjie Wang Mahmoud A. M. Labib SHORT DESCRIPTION A high-throughput, cost-effective device for sorting of single cells in a culture and analysis of their secreted products. BACKGROUND The demand for cost-effective cell analysis methods is expanding due to the increasing urge for the early detection,...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Autoimmune disease, Biomedical, Devices, Diagnostics, Drug screening, Personalized medicine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Biological Markers for Diagnosis of Diseases Associated with Major Depression
NU 2010-062 Inventors Eva Redei* Brian Andrus Abstract Northwestern researchers have discovered a set of genes whose mRNA levels differ in the blood of animals that show higher and lower levels of depressive behavior. While a subset of these genes expressed in the blood and brain regions is common between these two groups, there is another...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomarker, Diagnostics, Psychiatric disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Blood Markers for Diagnosing Diseases Associated with Major Depression
­NU 2010-062, NU 2013-167, and NU 2013-168 PRIMARY INVENTOR Eva Redei SHORT DESCRIPTION A diagnostic platform and method to accurately diagnose and predict treatment response in patients suffering from depression and post-traumatic stress disorder. BACKGROUND Psychiatric disorders, such as major depressive disorder (MDD) and post-traumatic stress...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomarker, Diagnostics, Psychiatric disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Microfluidic Device for Live Cell Manipulation and Analysis
NU 2020-191 INVENTORS Horacio Espinosa* Milan Mrksich* Prithvijit Mukherjee Eric Berns Cesar Patino SHORT DESCRIPTION A microfluidic platform for manipulation and analysis of live cells by delivering molecules or extracting and analyzing their internal contents at multiple timepoints without killing them ABSTRACT Current methods for investigating...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Devices, Microfluidics, Research tool, Vector/Plasmid
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
FIT-Flares for Detection of Intracellular Analytes in Live Cells
NU 2019-117B INVENTORS Chad Mirkin* Sasha Ebrahimi Devleena Samanta Ho Fung Cheng SHORT DESCRIPTION A new class of signaling aptamers which contain a single modification, yet can be used to detect a broad range of targets ABSTRACT Aptamers are oligonucleotide sequences that can be evolved to bind to various analytes of interest. Northwestern researchers...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomedical, Diagnostics, Nanoparticle, Research tool, Sensors
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Novel Sensitive Probes for Detection in Living cells and Complex Media
NU 2019-117B INVENTORS Chad Mirkin* Sasha Ebrahimi Devleena Samanta Ho Fung Cheng SHORT DESCRIPTION A new class of signaling aptamers which contain a single modification, yet can be used to detect a broad range of targets ABSTRACT Aptamers are oligonucleotide sequences that can be evolved to bind to various analytes of interest. Northwestern...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, IP/Patent Status > Pending
Platelet Factor 4 as a Biomarker of Defective Lymphatics
NU 2020-158 INVENTORS Guillermo Oliver* Stanley Rockson SHORT DESCRIPTION A new biomarker for identifying lymphatic vasculature diseases BACKGROUND Lymphatic vasculature defects often result in disfiguring, disabling, and, occasionally, life-threatening outcomes. Diagnostic tools for all of the lymphatic disorders are relatively limited, relying...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Assay, Biomarker, Diagnostics, Obesity, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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