Search Results - lei+wang

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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability

Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...

Published: 9/25/2023 | Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA

Keywords(s): Drug Discovery, Immunology

Category(s): Technology Classifications > Medical > Biotechnology

Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications

Summary Rhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...

Published: 9/21/2023 | Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano

Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents

Category(s): Imaging, Research Tools

Capillary-Channeled Polymer Fibers for Isolating Exosomes

This capillary-channeled polymer (C-CP) fiber technology is a cost efficient and highly selective method to isolate exosomes facilitating widespread use of these cellular fragments for biomarker research, medical diagnostics, and targeted delivery of therapeutics. Exosomes are lipid membrane-derived vesicles secreted by most types of cells, which hold...

Published: 1/5/2024 | Inventor(s): Richard Marcus, Terri Bruce, Lei Wang, Sisi Huang, Tyler Slonecki, Rhonda Powell

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - Drug Delivery

Category(s): Advanced Materials, Biomedical Sciences

Development of Polyvinylpyrrolidone Grafted Nanoparticles using New RAFT Agent

Reference #: 01106 The University of South Carolina is offering licensing opportunities for a new RAFT agent to efficiently restore antibiotic activity by using synthesized nanoparticles. Invention Description: The subject invention is a new reversible addition-fragmentation chain-transfer (RAFT) agent to conduct the surface-initiated RAFT polymerization...

Published: 5/27/2021 | Inventor(s): Brian Benicewicz (USC), Lei Wang

Keywords(s):

Category(s): Biomedical and Life Sciences, Chemistry and Biochemistry, Nanotechnology

Cyclodextrin Functionalized Nanoparticles for Quenching Bacterial Communications

Reference #: 01089 The University of South Carolina is offering licensing opportunities for a novel method of combating bacterial infections without using antibiotics.Invention Description: The subject invention disrupts bacterial chemical communication using nanoparticles engineered with cyclodextrin compounds that bind and remove the molecules...

Published: 2/23/2022 | Inventor(s): Lei Wang, Kirsten Miller, Alan Decho, Brian Benicewicz (USC)

Keywords(s):

Category(s): Nanotechnology, Chemistry and Biochemistry

Polyisoprene Grafted Nanoparticles

Reference #: 01058 The University of South Carolina is offering licensing opportunities for a method synthesizing polyisoprene grafted nanoparticles to prepare rubber on silica surfaces.Invention Description:The subject invention is a new method for polymerizing isoperene on silica nanoparticle surfaces that allows more dispersion of silica fillers...

Published: 2/6/2018 | Inventor(s): Brian Benicewicz, Lei Wang, Mohammad Mohammadkhani

Keywords(s):

Category(s): Nanotechnology, Chemistry and Biochemistry

Fabrication of Magnetic Nanoparticles

Reference #: 01023The University of South Carolina is offering licensing opportunities for this novel method of synthesizing iron oxide/silica core-shell magnetic nanoparticles.Invention Description:This invention is a new method to synthesize iron oxide/silica core-shell magnetic nanoparticles with a high saturation magnetization and controllable...

Published: 5/27/2021 | Inventor(s): Lei Wang, Brian Benicewicz (USC)

Keywords(s):

Category(s): Chemistry and Biochemistry, Nanotechnology