Search Results - richard+marcus

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Capillary-Channeled Polymer Fibers for Isolating Exosomes
This capillary-channeled polymer (C-CP) fiber technology is a cost efficient and highly selective method to isolate exosomes facilitating widespread use of these cellular fragments for biomarker research, medical diagnostics, and targeted delivery of therapeutics. Exosomes are lipid membrane-derived vesicles secreted by most types of cells, which hold...
Published: 10/8/2024   |   Inventor(s): Richard Marcus, Terri Bruce, Lei Wang, Sisi Huang, Tyler Slonecki, Rhonda Powell
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - Drug Delivery
Category(s): Advanced Materials, Biomedical Sciences
Reduced-Cost, Ambient Desorption Optical Emission Spectroscopy for Performing Elemental Analysis (2016-018)
This analytical instrument uses ambient desorption optical emission spectroscopy (AD-OES) to perform elemental analysis on samples as diverse as metallic thin films, solution residues, powders, and bulk metals – directly from the solid state. Ambient desorption refers to the capability to analyze substances in their native state, and the ability...
Published: 10/8/2024   |   Inventor(s): Richard Marcus, Htoo Paing, Xinyan Zhang
Keywords(s): Agriculture, Analytical/Instrumentation/Sensors-Non-Medical/NonBiological, Coatings, Manufacturing, Optical Fibers/Materials/Other
Category(s): Advanced Materials
Improved High-Density Functionality of Polymer Surfaces (2015-044)
This easy modification creates polymer surfaces with high-density functionality by using polyethylene terephthalate (PET) capillary-channeled polymer (C-CP fibers) as the support material. The low-cost modification provides the capability for fast protein separations for proteomics applications and downstream processing due to the improved binding capacity....
Published: 10/8/2024   |   Inventor(s): Richard Marcus, Liuwei Jiang
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological
Category(s): Advanced Materials
Use of Ribbed Polymer Fibers as Stationary/Support Phases for Chemical Separations by Liquid Chromatography or for Waste Stream Remediation
This technology features the usage of a novel cross-section of polymer fibers for various applications such as liquid chromatography to separate, quantify, and analyze contents of a chemical mixture. Bundles of the novel high surface area fibers such as the 4DGTM fibers (see CURF reference 00-024) are packed in columns. Different polymer compositions...
Published: 10/8/2024   |   Inventor(s): Richard Marcus
Keywords(s):  
Category(s): Advanced Materials
Functionalized Modification of Polymers for HPLC
These polymer fibers, used as stationary phases in high-performance liquid chromatography (HPLC), enable a high level of selectivity and throughput, thus increasing efficiency. Chromatography is a method used by scientists to separate organic and inorganic compounds for further analysis. Currently, over 60% of chemical analysis worldwide is done in...
Published: 10/8/2024   |   Inventor(s): Kenneth Christensen, Richard Marcus
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Polymers/Composites, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Biotechnology
Fiber Bundle Cartridges as Chemical Separation Media
Monolithic cartridges including a plurality of nominally aligned polymer fibers can be used as stationary phase materials for liquid chromatography separations. Bundles of fibers are packed together so as to form capillary channels between the fibers. Different polymer compositions permit the “chemical tuning” of the separation process....
Published: 10/8/2024   |   Inventor(s): Richard Marcus, Rayman Stanelle, Igor Luzinov, Philip Brown, Yonnie Wu
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Analytical/Instrumentation/Sensors-Non-Medical/NonBiological, Bioprocessing/Biotechnology, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Advanced Materials