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Search Results - brendan+deal
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Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations. Key Benefits Tunable oligos increase specificity and cooperative binding to the disease target of interest. Distinguishes between cis- and trans mutations. Identifies different strains of...
Published: 10/28/2024
|
Inventor(s):
Brendan Deal
,
Khalid Salaita
,
Rong Ma
,
James Kindt
Keywords(s):
COVID19
,
Genetic Disorders
Category(s):
TechPub Algolia > Micro and Nanotechnology
,
TechPub Algolia > Diagnostics
Engineering Tighter Binding Spherical Nucleic Acids
Application Method to enhance the affinity of spherical nucleic acids for their targets. Key Benefits Facile method for molecular printing on surface of NP. Massive improvement of SNA’s binding affinity to the target can provide strategies in applications for therapeutics and diagnostics. May maximize DNA density on the NP surface. Market...
Published: 10/28/2024
|
Inventor(s):
Brendan Deal
,
Khalid Salaita
Keywords(s):
Drug Delivery
Category(s):
TechPub Algolia > Drug Discovery
,
TechPub Algolia > Micro and Nanotechnology