Search Results - curtis+henry

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Non-invasive Probes to Determine Efficacy of Cancer Therapies
Application A real-time, non-invasive probe to determine the efficacy of cancer immunotherapies. Key Benefits Determines immunotherapy success in patients. CAR cells can be tested before putting it back in the patients. Simple diagnostic with readout in 30 minutes compared to 2-3 days. Market Summary Lymphoblastic leukemia is one of the most...
Published: 7/30/2024   |   Inventor(s): Anna Kellner, Khalid Salaita, Curtis Henry
Keywords(s): Oncology, Pediatrics
Category(s): TechPub Algolia > Diagnostics
Interleukin-37 to Enhance Effectiveness of CAR T-cell Therapy
­ Application IL-37-expressing CAR T-cells to treat B-cell acute lymphoblastic leukemia. Key Benefits Boosts the function of aged T-cells. Enhances the effectiveness of CAR T-cell therapy. Therapeutic potential to overcome aging-associated immune-senescence. Potent suppressor of chronic inflammation or pro-inflammatory cytokines. Market...
Published: 7/30/2024   |   Inventor(s): Curtis Henry, Sunil Raikar, Sarwish Rafiq
Keywords(s): Immunology/Inflammation, Oncology
Category(s): TechPub Algolia > Therapeutics
Immune Cell Redirecting Therapies
­Application A therapeutic against B cell cancers developed using a novel screening method for rapid drug discovery. Key Benefits Screening approach can be used for future drug discovery. Therapeutic incorporates cytokine therapy with reduced risk of off-target toxicity. Therapeutic is of interest for the treatment of B cell cancers and autoimmune...
Published: 8/22/2024   |   Inventor(s): Erik Dreaden, Priscilla Do, Curtis Henry, Christopher Porter
Keywords(s): Oncology
Category(s): TechPub Algolia > Therapeutics
Galectin-9 Directed CAR T-cells for Overcoming Resistance to Chemotherapy in Hematological Malignancies
Application Anti-human Galectin-9-directed chimeric antigen receptor (CAR) T-cells for treatment of hematological malignancies (B-ALL, T-ALL, and DLBCL) in normal, overweight, and obese patients. Key Benefits Can be used as a stand-alone or in-combination product to treat patients with hematological malignancies, particularly overweight and obese...
Published: 7/30/2024   |   Inventor(s): Curtis Henry, Miyoung (Mi-Young) Lee, Sunil Raikar, Jamie Hamilton, Anthony Ross
Keywords(s): Antibody, Cell/Gene Therapy, Oncology, Pediatrics
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery